Regulation of tumor cell mitochondrial homeostasis by an organelle-specific Hsp90 chaperone network BH Kang, J Plescia, T Dohi, J Rosa, SJ Doxsey, DC Altieri Cell 131 (2), 257-270, 2007 | 539 | 2007 |
Hsp60 regulation of tumor cell apoptosis JC Ghosh, T Dohi, BH Kang, DC Altieri Journal of Biological Chemistry 283 (8), 5188-5194, 2008 | 391 | 2008 |
Combinatorial drug design targeting multiple cancer signaling networks controlled by mitochondrial Hsp90 BH Kang, J Plescia, HY Song, M Meli, G Colombo, K Beebe, B Scroggins, ... The Journal of clinical investigation 119 (3), 454-464, 2009 | 267 | 2009 |
Development of a mitochondria-targeted Hsp90 inhibitor based on the crystal structures of human TRAP1 C Lee, HK Park, H Jeong, J Lim, AJ Lee, KY Cheon, CS Kim, AP Thomas, ... Journal of the American Chemical Society 137 (13), 4358-4367, 2015 | 139 | 2015 |
Unleashing the full potential of Hsp90 inhibitors as cancer therapeutics through simultaneous inactivation of Hsp90, Grp94, and TRAP1 HK Park, NG Yoon, JE Lee, S Hu, S Yoon, SY Kim, JH Hong, D Nam, ... Experimental & molecular medicine 52 (1), 79-91, 2020 | 108 | 2020 |
Interplay between TRAP1 and sirtuin-3 modulates mitochondrial respiration and oxidative stress to maintain stemness of glioma stem cells HK Park, JH Hong, YT Oh, SS Kim, J Yin, AJ Lee, YC Chae, JH Kim, ... Cancer research 79 (7), 1369-1382, 2019 | 107 | 2019 |
Regulation of survivin stability by the aryl hydrocarbon receptor-interacting protein BH Kang, DC Altieri Journal of Biological Chemistry 281 (34), 24721-24727, 2006 | 106 | 2006 |
Preclinical characterization of mitochondria-targeted small molecule hsp90 inhibitors, gamitrinibs, in advanced prostate cancer BH Kang, MD Siegelin, J Plescia, CM Raskett, DS Garlick, T Dohi, JB Lian, ... Clinical Cancer Research 16 (19), 4779-4788, 2010 | 105 | 2010 |
TRAP1 regulation of mitochondrial life or death decision in cancer cells and mitochondria-targeted TRAP1 inhibitors BH Kang KOREAN SOCIETY BIOCHEMISTRY & MOLECULAR BIOLOGY, 2012 | 82 | 2012 |
Combination treatment with doxorubicin and gamitrinib synergistically augments anticancer activity through enhanced activation of Bim HK Park, JE Lee, J Lim, DE Jo, SA Park, PG Suh, BH Kang BMC cancer 14, 1-9, 2014 | 71 | 2014 |
Targeted inhibition of mitochondrial Hsp90 suppresses localised and metastatic prostate cancer growth in a genetic mouse model of disease BH Kang, M Tavecchio, HL Goel, CC Hsieh, DS Garlick, CM Raskett, ... British journal of cancer 104 (4), 629-634, 2011 | 71 | 2011 |
Compartmentalized cancer drug discovery targeting mitochondrial Hsp90 chaperones BH Kang, DC Altieri Oncogene 28 (42), 3681-3688, 2009 | 66 | 2009 |
Developmental control of apoptosis by the immunophilin aryl hydrocarbon receptor-interacting protein (AIP) involves mitochondrial import of the survivin protein BH Kang, F Xia, R Pop, T Dohi, M Socolovsky, DC Altieri Journal of Biological Chemistry 286 (19), 16758-16767, 2011 | 55 | 2011 |
Paralog specificity determines subcellular distribution, action mechanism, and anticancer activity of TRAP1 inhibitors HK Park, H Jeong, E Ko, G Lee, JE Lee, SK Lee, AJ Lee, JY Im, S Hu, ... Journal of Medicinal Chemistry 60 (17), 7569-7578, 2017 | 51 | 2017 |
Mitochondrial Hsp90s suppress calcium-mediated stress signals propagating from mitochondria to the ER in cancer cells HK Park, JE Lee, J Lim, BH Kang Molecular cancer 13, 1-14, 2014 | 50 | 2014 |
Cytotoxic effects of Tenebrio molitor larval extracts against hepatocellular carcinoma JE Lee, AJ Lee, DE Jo, JH Cho, K Youn, EY Yun, JS Hwang, M Jun, ... Journal of the Korean Society of Food Science and Nutrition 44 (2), 200-207, 2015 | 45 | 2015 |
PDZ domain-containing 1 (PDZK1) protein regulates phospholipase C-β3 (PLC-β3)-specific activation of somatostatin by forming a ternary complex with PLC-β3 and somatostatin … JK Kim, O Kwon, J Kim, EK Kim, HK Park, JE Lee, KL Kim, JW Choi, S Lim, ... Journal of Biological Chemistry 287 (25), 21012-21024, 2012 | 35 | 2012 |
The structure of procaspase 6 is similar to that of active mature caspase 6 BH Kang, E Ko, OK Kwon, KY Choi Biochemical Journal 364 (3), 629-634, 2002 | 31 | 2002 |
Hepatoprotective and anticancer activities of Allomyrina dichotoma larvae JE Lee, DE Jo, AJ Lee, HK Park, K Youn, EY Yun, JS Hwang, M Jun, ... Journal of Life Science 25 (3), 307-316, 2015 | 30 | 2015 |
OGA heterozygosity suppresses intestinal tumorigenesis in Apcmin/+ mice YR Yang, HJ Jang, S Yoon, YH Lee, D Nam, IS Kim, H Lee, H Kim, ... Oncogenesis 3 (7), e109-e109, 2014 | 30 | 2014 |