Activation of mTOR/IκB-α/NF-κB pathway contributes to LPS-induced hypotension and inflammation in rats M Temiz-Resitoglu, SP Kucukkavruk, DS Guden, P Cecen, AN Sari, ... European Journal of Pharmacology 802, 7-19, 2017 | 82 | 2017 |
Contribution of iNOS/sGC/PKG pathway, COX-2, CYP4A1, and gp91phox to the protective effect of 5, 14-HEDGE, a 20-HETE mimetic, against vasodilation, hypotension, tachycardia … B Tunctan, B Korkmaz, AN Sari, M Kacan, D Unsal, MS Serin, ... Nitric Oxide 33, 18-41, 2013 | 77 | 2013 |
Studies on the vascular effects of the fractions and phenolic compounds isolated from Viscum album ssp. album D Deliorman, İ Çalış, F Ergun, BSU Doğan, CK Buharalıoğlu, I Kanzık Journal of ethnopharmacology 72 (1-2), 323-329, 2000 | 71 | 2000 |
Angiotensin II-induced migration of vascular smooth muscle cells is mediated by p38 mitogen-activated protein kinase-activated c-Src through spleen tyrosine kinase and … BE Mugabe, FA Yaghini, CY Song, CK Buharalioglu, CM Waters, ... Journal of Pharmacology and Experimental Therapeutics 332 (1), 116-124, 2010 | 65 | 2010 |
Angiotensin II-induced process of angiogenesis is mediated by spleen tyrosine kinase via VEGF receptor-1 phosphorylation CK Buharalioglu, CY Song, FA Yaghini, HUB Ghafoor, M Motiwala, ... American Journal of Physiology-Heart and Circulatory Physiology 301 (3 …, 2011 | 57 | 2011 |
Increased production of nitric oxide contributes to renal oxidative stress in endotoxemic rat B Tunctan, B Korkmaz, H Yildirim, L Tamer, U Atik, CK Buharalioglu Am J Infect Dis 1 (2), 111-115, 2005 | 47 | 2005 |
A novel treatment strategy for sepsis and septic shock based on the interactions between prostanoids, nitric oxide, and 20-hydroxyeicosatetraenoic acid B Tunctan, B Korkmaz, A Nihal Sari, M Kacan, D Unsal, M Sami Serin, ... Anti-Inflammatory & Anti-Allergy Agents in Medicinal Chemistryrrent …, 2012 | 46 | 2012 |
A synthetic analogue of 20‐HETE, 5, 14‐HEDGE, reverses endotoxin‐induced hypotension via increased 20‐HETE levels associated with decreased iNOS protein expression and … T Cuez, B Korkmaz, CK Buharalioglu, S Sahan‐Firat, J Falck, KU Malik, ... Basic & clinical pharmacology & toxicology 106 (5), 378-388, 2010 | 43 | 2010 |
Activation of MEK1/ERK1/2/iNOS/sGC/PKG pathway associated with peroxynitrite formation contributes to hypotension and vascular hyporeactivity in endotoxemic rats B Korkmaz, K Buharalioglu, S Sahan-Firat, T Cuez, AT Demiryurek, ... Nitric Oxide 24 (3), 160-172, 2011 | 41 | 2011 |
Protective effect of cromakalim and diazoxide, and proulcerogenic effect of glibenclamide on indomethacin-induced gastric injury F Akar, BS Uydeş-Doğan, CK Buharalıoğlu, G Abban, A Heinemann, ... European journal of pharmacology 374 (3), 461-470, 1999 | 40 | 1999 |
5, 14-HEDGE, a 20-HETE mimetic, reverses hypotension and improves survival in a rodent model of septic shock: contribution of soluble epoxide hydrolase, CYP2C23, MEK1/ERK1/2 … B Tunctan, B Korkmaz, AN Sari, M Kacan, D Unsal, MS Serin, ... Prostaglandins & other lipid mediators 102, 31-41, 2013 | 37 | 2013 |
Nitric oxide reverses endotoxin-induced inflammatory hyperalgesia via inhibition of prostacyclin production in mice B Tunctan, E Ozveren, B Korkmaz, CK Buharalioglu, L Tamer, ... Pharmacological research 53 (2), 177-192, 2006 | 37 | 2006 |
Protection by mTOR inhibition on zymosan-induced systemic inflammatory response and oxidative/nitrosative stress: contribution of mTOR/MEK1/ERK1/2/IKKβ/IκB-α/NF-κB signalling … S Sahan-Firat, M Temiz-Resitoglu, DS Guden, SP Kucukkavruk, ... Inflammation 41, 276-298, 2018 | 35 | 2018 |
Effects of 5, 14-HEDGE, a 20-HETE mimetic, on lipopolysaccharide-induced changes in MyD88/TAK1/IKKβ/IκB-α/NF-κB pathway and circulating miR-150, miR-223, and miR-297 levels in … AN Sari, B Korkmaz, MS Serin, M Kacan, D Unsal, CK Buharalioglu, ... Inflammation research 63, 741-756, 2014 | 32 | 2014 |
Contribution of vasoactive eicosanoids and nitric oxide production to the effect of selective cyclooxygenase‐2 inhibitor, NS‐398, on endotoxin‐induced hypotension in rats B Tunctan, B Korkmaz, T Cuez, C Kemal Buharalioglu, S Sahan‐Firat, ... Basic & clinical pharmacology & toxicology 107 (5), 877-882, 2010 | 32 | 2010 |
Contribution of RhoA/Rho-kinase/MEK1/ERK1/2/iNOS pathway to ischemia/reperfusion-induced oxidative/nitrosative stress and inflammation leading to distant and target organ … AN Sari, M Kacan, D Unsal, SS Firat, CK Buharalioglu, O Vezir, ... European journal of pharmacology 723, 234-245, 2014 | 29 | 2014 |
The reactivity of serotonin, acetylcholine and kcl-induced contractions to relaxant agents in the rat gastric fundus CK Buharalioğlu, F Akar Pharmacological research 45 (4), 325-331, 2002 | 28 | 2002 |
A 20-hydroxyeicosatetraenoic acid agonist, N-[20-hydroxyeicosa-5 (Z), 14 (Z)-dienoyl] glycine, opposes the fall in blood pressure and vascular reactivity in endotoxin-treated rats B Tunctan, B Korkmaz, CK Buharalioglu, SS Firat, S Anjaiah, J Falck, ... Shock 30 (3), 329-335, 2008 | 24 | 2008 |
Inhibition of extracellular signal-regulated kinase (ERK1/2) activity reverses endotoxin-induced hypotension via decreased nitric oxide production in rats B Tunctan, B Korkmaz, ZN Dogruer, L Tamer, U Atik, CK Buharalioglu Pharmacological research 56 (1), 56-64, 2007 | 23 | 2007 |
NS-398 reverses hypotension in endotoxemic rats: contribution of eicosanoids, NO, and peroxynitrite B Tunctan, AN Sari, M Kacan, D Unsal, CK Buharalioglu, S Sahan-Firat, ... Prostaglandins & other lipid mediators 104, 93-108, 2013 | 22 | 2013 |