T-cell protein tyrosine phosphatase deletion results in progressive systemic inflammatory disease KM Heinonen, FP Nestel, EW Newell, G Charette, TA Seemayer, ... Blood 103 (9), 3457-3464, 2004 | 207 | 2004 |
Genetic ablation of protein tyrosine phosphatase 1B accelerates lymphomagenesis of p53-null mice through the regulation of B-cell development N Dubé, A Bourdeau, KM Heinonen, A Cheng, A Lee Loy, ML Tremblay Cancer research 65 (21), 10088-10095, 2005 | 116 | 2005 |
Protein tyrosine phosphatase 1B negatively regulates macrophage development through CSF-1 signaling KM Heinonen, N Dubé, A Bourdeau, WS Lapp, ML Tremblay Proceedings of the National Academy of Sciences 103 (8), 2776-2781, 2006 | 100 | 2006 |
Wnt4 enhances murine hematopoietic progenitor cell expansion through a planar cell polarity-like pathway KM Heinonen, JR Vanegas, D Lew, J Krosl, C Perreault PloS one 6 (4), e19279, 2011 | 96 | 2011 |
Protein tyrosine phosphatases PTP-1B and TC-PTP play nonredundant roles in macrophage development and IFN-γ signaling KM Heinonen, A Bourdeau, KM Doody, ML Tremblay Proceedings of the National Academy of Sciences 106 (23), 9368-9372, 2009 | 90 | 2009 |
Infection-adapted emergency hematopoiesis promotes visceral leishmaniasis BM Abidin, A Hammami, S Stäger, KM Heinonen PLoS Pathogens 13 (8), e1006422, 2017 | 82 | 2017 |
The signaling protein Wnt4 enhances thymopoiesis and expands multipotent hematopoietic progenitors through β-catenin-independent signaling I Louis, KM Heinonen, J Chagraoui, S Vainio, G Sauvageau, C Perreault Immunity 29 (1), 57-67, 2008 | 76 | 2008 |
Wnt4 regulates thymic cellularity through the expansion of thymic epithelial cells and early thymic progenitors KM Heinonen, J Ruiz Vanegas, S Brochu, J Shan, SJ Vainio, C Perreault Blood, The Journal of the American Society of Hematology 118 (19), 5163-5173, 2011 | 75 | 2011 |
Wnt4, a pleiotropic signal for controlling cell polarity, basement membrane integrity, and antimullerian hormone expression during oocyte maturation in the female follicle R Prunskaite‐Hyyrylainen, J Shan, A Railo, KM Heinonen, I Miinalainen, ... The FASEB Journal 28 (4), 1568-1581, 2014 | 71 | 2014 |
TC-PTP–deficient bone marrow stromal cells fail to support normal B lymphopoiesis due to abnormal secretion of interferon-γ A Bourdeau, N Dubé, KM Heinonen, JF Théberge, KM Doody, ... Blood 109 (10), 4220-4228, 2007 | 63 | 2007 |
HIF-1α is a key regulator in potentiating suppressor activity and limiting the microbicidal capacity of MDSC-like cells during visceral leishmaniasis A Hammami, BM Abidin, T Charpentier, A Fabié, AP Duguay, ... PLoS Pathogens 13 (9), e1006616, 2017 | 58 | 2017 |
HIF-1α hampers dendritic cell function and Th1 generation during chronic visceral leishmaniasis A Hammami, BM Abidin, KM Heinonen, S Stäger Scientific reports 8 (1), 3500, 2018 | 55 | 2018 |
SMAD3 prevents graft-versus-host disease by restraining Th1 differentiation and granulocyte-mediated tissue damage M Giroux, JS Delisle, SD Gauthier, KM Heinonen, J Hinsinger, B Houde, ... Blood, The Journal of the American Society of Hematology 117 (5), 1734-1744, 2011 | 53 | 2011 |
Competitive transplants to evaluate hematopoietic stem cell fitness EO Kwarteng, KM Heinonen Journal of visualized experiments: JoVE, 54345, 2016 | 38 | 2016 |
Development and functional properties of thymic and extrathymic T lymphocytes KM Heinonen, C Perreault Critical Reviews™ in Immunology 28 (5), 2008 | 35 | 2008 |
Frizzled-6 regulates hematopoietic stem/progenitor cell survival and self-renewal BM Abidin, E Owusu Kwarteng, KM Heinonen The Journal of Immunology 195 (5), 2168-2176, 2015 | 32 | 2015 |
Frontline Science: Wnt/β-catenin pathway promotes early engraftment of fetal hematopoietic stem/progenitor cells EO Kwarteng, R Hétu-Arbour, KM Heinonen Journal of Leukocyte Biology 103 (3), 381-393, 2018 | 20 | 2018 |
Cell-intrinsic Wnt4 promotes hematopoietic stem and progenitor cell self-renewal R Hétu-Arbour, M Tlili, FL Bandeira Ferreira, BM Abidin, EO Kwarteng, ... Stem Cells 39 (9), 1207-1220, 2021 | 11 | 2021 |
Protein tyrosine phosphatase 1B in hematopoiesis KM Heinonen, ML Tremblay Cell Cycle 5 (10), 1053-1056, 2006 | 10 | 2006 |
Persistent Cutaneous Leishmania major Infection Promotes Infection-Adapted Myelopoiesis FL Bandeira Ferreira, O Séguin, A Descoteaux, KM Heinonen Microorganisms 10 (3), 535, 2022 | 7 | 2022 |