オープン アクセスを義務付けられた論文 - Craig Hughes詳細
一般には非公開: 1 件
All-trans retinoic acid impairs platelet function and thrombus formation and inhibits protein kinase CßI/δ phosphorylation
Q Luo, G Wei, X Wang, X Xu, W Ju, Z Li, EE Gardiner, RK Andrews, ...
Thrombosis and Haemostasis 119 (10), 1655-1664, 2019
委任: National Health and Medical Research Council, Australia, National Natural …
一般公開: 32 件
Fibrin activates GPVI in human and mouse platelets
OM Alshehri, CE Hughes, S Montague, SK Watson, J Frampton, M Bender, ...
Blood, The Journal of the American Society of Hematology 126 (13), 1601-1608, 2015
委任: German Research Foundation, British Heart Foundation, Wellcome Trust
CLEC-2 activates Syk through dimerization
CE Hughes, AY Pollitt, J Mori, JA Eble, MG Tomlinson, JH Hartwig, ...
Blood, The Journal of the American Society of Hematology 115 (14), 2947-2955, 2010
委任: German Research Foundation, British Heart Foundation
CLEC-2 and Syk in the megakaryocytic/platelet lineage are essential for development
BA Finney, E Schweighoffer, L Navarro-Núñez, C Bénézech, F Barone, ...
Blood, The Journal of the American Society of Hematology 119 (7), 1747-1756, 2012
委任: British Heart Foundation, Cancer Research UK, Government of Spain
The novel Syk inhibitor R406 reveals mechanistic differences in the initiation of GPVI and CLEC‐2 signaling in platelets
JC Spalton, J Mori, AY Pollitt, CE Hughes, JA Eble, SP Watson
Journal of Thrombosis and Haemostasis 7 (7), 1192-1199, 2009
委任: British Heart Foundation
Immobilized fibrinogen activates human platelets through glycoprotein VI
PH Mangin, MB Onselaer, N Receveur, N Le Lay, AT Hardy, C Wilson, ...
haematologica 103 (5), 898, 2018
委任: British Heart Foundation
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib
AP Bye, AJ Unsworth, MJ Desborough, CAT Hildyard, N Appleby, D Bruce, ...
Blood advances 1 (26), 2610-2623, 2017
委任: British Heart Foundation, National Institute for Health Research, UK
CLEC‐2 is not required for platelet aggregation at arteriolar shear
CE Hughes, L NAVARRO‐NÚÑEZ, BA Finney, D MOURÃO‐SÁ, AY Pollitt, ...
Journal of Thrombosis and Haemostasis 8 (10), 2328-2332, 2010
委任: British Heart Foundation
Syk and Src family kinases regulate C-type lectin receptor 2 (CLEC-2)-mediated clustering of podoplanin and platelet adhesion to lymphatic endothelial cells
AY Pollitt, NS Poulter, E Gitz, L Navarro-Nunez, YJ Wang, CE Hughes, ...
Journal of Biological chemistry 289 (52), 35695-35710, 2014
委任: US National Institutes of Health, UK Medical Research Council, Wellcome Trust
Fucoidan is a novel platelet agonist for the C-type lectin-like receptor 2 (CLEC-2)
BK Manne, TM Getz, CE Hughes, O Alshehri, C Dangelmaier, UP Naik, ...
Journal of Biological Chemistry 288 (11), 7717-7726, 2013
委任: US National Institutes of Health
Involvement of Src kinases and PLCγ2 in clot retraction
K Suzuki-Inoue, CE Hughes, O Inoue, M Kaneko, O Cuyun-Lira, ...
Thrombosis research 120 (2), 251-258, 2007
委任: British Heart Foundation
Inhibition of Btk by Btk-specific concentrations of ibrutinib and acalabrutinib delays but does not block platelet aggregation mediated by glycoprotein VI
PLR Nicolson, CE Hughes, S Watson, SH Nock, AT Hardy, CN Watson, ...
haematologica 103 (12), 2097, 2018
委任: British Heart Foundation
Low-dose Btk inhibitors selectively block platelet activation by CLEC-2
PLR Nicolson, SH Nock, J Hinds, L Garcia-Quintanilla, CW Smith, ...
Haematologica 106 (1), 208, 2020
委任: German Research Foundation, British Heart Foundation
The N-terminal SH2 domain of Syk is required for (hem) ITAM, but not integrin, signaling in mouse platelets
CE Hughes, BA Finney, F Koentgen, KL Lowe, SP Watson
Blood, The Journal of the American Society of Hematology 125 (1), 144-154, 2015
委任: British Heart Foundation, Wellcome Trust
Differential roles of the PKC novel isoforms, PKCδ and PKCε, in mouse and human platelets
CJ Pears, K Thornber, JM Auger, CE Hughes, B Grygielska, MB Protty, ...
PLoS One 3 (11), e3793, 2008
委任: British Heart Foundation
Globular adiponectin induces platelet activation through the collagen receptor GPVI-Fc receptor γ chain complex
R Riba, CE Hughes, A Graham, SP Watson, KM Naseem
Journal of Thrombosis and Haemostasis 6 (6), 1012-1020, 2008
委任: British Heart Foundation
Minimal regulation of platelet activity by PECAM-1
TS Dhanjal, EA Ross, JM Auger, OJT McCarty, CE Hughes, YA Senis, ...
Platelets 18 (1), 56-67, 2007
委任: British Heart Foundation
Critical role for an acidic amino acid region in platelet signaling by the HemITAM (hemi-immunoreceptor tyrosine-based activation motif) containing receptor CLEC-2 (C-type …
CE Hughes, U Sinha, A Pandey, JA Eble, CA O'Callaghan, SP Watson
Journal of Biological Chemistry 288 (7), 5127-5135, 2013
委任: British Heart Foundation
Activation of glycoprotein VI (GPVI) and C-type lectin-like receptor-2 (CLEC-2) underlies platelet activation by diesel exhaust particles and other charged/hydrophobic ligands
OM Alshehri, S Montague, S Watson, P Carter, N Sarker, BK Manne, ...
Biochemical Journal 468 (3), 459-473, 2015
委任: British Heart Foundation, UK Medical Research Council, National Institute …
GPVI potentiation of platelet activation by thrombin and adhesion molecules independent of Src kinases and Syk
SC Hughan, CE Hughes, OJT McCarty, E Schweighoffer, I Soultanova, ...
Arteriosclerosis, thrombosis, and vascular biology 27 (2), 422-429, 2007
委任: British Heart Foundation
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