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The hypothalamus predates the origin of vertebrates LA Lemaire, C Cao, PH Yoon, J Long, M Levine Science Advances 7 (18), eabf7452, 2021 | 38 | 2021 |
Rapid DNA unwinding accelerates genome editing by engineered CRISPR-Cas9 AR Eggers, K Chen, KM Soczek, OT Tuck, EE Doherty, B Xu, MI Trinidad, ... Cell 187 (13), 3249-3261. e14, 2024 | 17 | 2024 |
The extracellular matrix integrates mitochondrial homeostasis H Zhang, CK Tsui, G Garcia, LK Joe, H Wu, A Maruichi, W Fan, ... Cell 187 (16), 4289-4304. e26, 2024 | 16 | 2024 |
Eukaryotic RNA-guided endonucleases evolved from a unique clade of bacterial enzymes PH Yoon, P Skopintsev, H Shi, LX Chen, BA Adler, M Al-Shimary, ... Nucleic Acids Research, 2023 | 16 | 2023 |
CasPEDIA Database: A Functional Classification System for Class 2 CRISPR-Cas Enzymes BA Adler, MI Trinidad, D Bellieny-Rabelo, E Zhang, HM Karp, ... Nucleic Acids Research, 2023 | 15 | 2023 |
RNA language models predict mutations that improve RNA function Y Shulgina, MI Trinidad, CJ Langeberg, H Nisonoff, S Chithrananda, ... bioRxiv, 2024 | 6 | 2024 |
Structure-guided discovery of ancestral CRISPR-Cas13 ribonucleases PH Yoon, Z Zhang, KJ Loi, BA Adler, A Lahiri, K Vohra, H Shi, DB Rabelo, ... Science 385 (6708), 538-543, 2024 | 4 | 2024 |
To TnpB or not TnpB? Cas12 is the answer PH Yoon, BA Adler, JA Doudna Nature Chemical Biology 19 (3), 263-264, 2023 | 3 | 2023 |
Toph (true retrieval of proteins homologs): Adapting a contrastive question-answering framework for protein search R Boger, A Lu, S Chithrananda, K Yang, P Skopintsev, B Adler, E Wallace, ... ICML workshop on computational biology, 2023 | 3 | 2023 |
Functional protein mining with conformal guarantees RS Boger, S Chithrananda, AN Angelopoulos, PH Yoon, MI Jordan, ... Nature Communications 16 (1), 85, 2025 | | 2025 |