g_membed: Efficient insertion of a membrane protein into an equilibrated lipid bilayer with minimal perturbation MG Wolf, M Hoefling, C Aponte‐Santamaría, H Grubmüller, G Groenhof Journal of computational chemistry 31 (11), 2169-2174, 2010 | 393 | 2010 |
Crystal structure of a yeast aquaporin at 1.15 Å reveals a novel gating mechanism G Fischer, U Kosinska-Eriksson, C Aponte-Santamaría, M Palmgren, ... PLoS biology 7 (6), e1000130, 2009 | 209 | 2009 |
von Willebrand factor directly interacts with DNA from neutrophil extracellular traps S Grässle, V Huck, KI Pappelbaum, C Gorzelanny, C Aponte-Santamaría, ... Arteriosclerosis, thrombosis, and vascular biology 34 (7), 1382-1389, 2014 | 185 | 2014 |
Aquaporin-9 protein is the primary route of hepatocyte glycerol uptake for glycerol gluconeogenesis in mice S Jelen, S Wacker, C Aponte-Santamaría, M Skott, A Rojek, U Johanson, ... Journal of Biological Chemistry 286 (52), 44319-44325, 2011 | 155 | 2011 |
Mechanism of focal adhesion kinase mechanosensing J Zhou, C Aponte-Santamaría, S Sturm, JT Bullerjahn, A Bronowska, ... PLoS computational biology 11 (11), e1004593, 2015 | 144 | 2015 |
GROmaρs: A GROMACS-based toolset to analyze density maps derived from molecular dynamics simulations R Briones, C Blau, C Kutzner, BL de Groot, C Aponte-Santamaría Biophysical journal 116 (1), 4-11, 2019 | 96 | 2019 |
Autoregulation of von Willebrand factor function by a disulfide bond switch D Butera, F Passam, L Ju, KM Cook, H Woon, C Aponte-Santamaría, ... Science advances 4 (2), eaaq1477, 2018 | 94 | 2018 |
Force-sensitive autoinhibition of the von Willebrand factor is mediated by interdomain interactions C Aponte-Santamaría, V Huck, S Posch, AK Bronowska, S Grässle, ... Biophysical journal 108 (9), 2312-2321, 2015 | 90 | 2015 |
Voltage-regulated water flux through aquaporin channels in silico JS Hub, C Aponte-Santamaría, H Grubmüller, BL de Groot Biophysical journal 99 (12), L97-L99, 2010 | 85 | 2010 |
Molecular driving forces defining lipid positions around aquaporin-0 C Aponte-Santamaría, R Briones, AD Schenk, T Walz, BL de Groot Proceedings of the National Academy of Sciences 109 (25), 9887-9892, 2012 | 75 | 2012 |
von Willebrand factor is dimerized by protein disulfide isomerase S Lippok, K Kolšek, A Löf, D Eggert, W Vanderlinden, JP Müller, G König, ... Blood, The Journal of the American Society of Hematology 127 (9), 1183-1191, 2016 | 62 | 2016 |
Mechano-redox control of integrin de-adhesion F Passam, J Chiu, L Ju, A Pijning, Z Jahan, R Mor-Cohen, A Yeheskel, ... Elife 7, e34843, 2018 | 60 | 2018 |
Accessibility explains preferred thiol-disulfide isomerization in a protein domain K Kolšek, C Aponte-Santamaría, F Gräter Scientific reports 7 (1), 9858, 2017 | 52 | 2017 |
The identification of novel, high affinity AQP9 inhibitors in an intracellular binding site SJ Wacker, C Aponte-Santamaría, P Kjellbom, S Nielsen, BL de Groot, ... Molecular membrane biology 30 (3), 246-260, 2013 | 43 | 2013 |
Structure and dynamics of the platelet integrin-binding C4 domain of von Willebrand factor ER Xu, S von Bülow, PC Chen, PJ Lenting, K Kolšek, ... Blood, The Journal of the American Society of Hematology 133 (4), 366-376, 2019 | 42 | 2019 |
von Willebrand disease type 2A phenotypes IIC, IID and IIE: A day in the life of shear-stressed mutant von Willebrand factor MA Brehm, V Huck, C Aponte-Santamaría, T Obser, S Grässle, F Oyen, ... Thrombosis and haemostasis 112 (07), 96-108, 2014 | 40 | 2014 |
Understanding conformational dynamics of complex lipid mixtures relevant to biology R Friedman, S Khalid, C Aponte-Santamaría, E Arutyunova, M Becker, ... The Journal of membrane biology 251, 609-631, 2018 | 38 | 2018 |
Mutual A domain interactions in the force sensing protein von Willebrand factor S Posch, C Aponte-Santamaría, R Schwarzl, A Karner, M Radtke, F Gräter, ... Journal of structural biology 197 (1), 57-64, 2017 | 38 | 2017 |
Dynamics and energetics of solute permeation through the Plasmodium falciparum aquaglyceroporin C Aponte-Santamaría, JS Hub, BL de Groot Physical Chemistry Chemical Physics 12 (35), 10246-10254, 2010 | 34 | 2010 |
Localization and ordering of lipids around aquaporin-0: protein and lipid mobility effects R Briones, C Aponte-Santamaría, BL de Groot Frontiers in Physiology 8, 124, 2017 | 31 | 2017 |