フォロー
Amanda J Unsworth
Amanda J Unsworth
University of Leeds
確認したメール アドレス: mmu.ac.uk
タイトル
引用先
引用先
Platelet signaling: a complex interplay between inhibitory and activatory networks
AP Bye, AJ Unsworth, JM Gibbins
Journal of Thrombosis and Haemostasis 14 (5), 918-930, 2016
2192016
Severe platelet dysfunction in NHL patients receiving ibrutinib is absent in patients receiving acalabrutinib
AP Bye, AJ Unsworth, MJ Desborough, CAT Hildyard, N Appleby, D Bruce, ...
Blood advances 1 (26), 2610-2623, 2017
1352017
Ibrutinib Inhibits Platelet Integrin αIIbβ3 Outside-In Signaling and Thrombus Stability But Not Adhesion to Collagen
AP Bye, AJ Unsworth, S Vaiyapuri, AR Stainer, MJ Fry, JM Gibbins
Arteriosclerosis, thrombosis, and vascular biology 35 (11), 2326-2335, 2015
1092015
The metabolites of the dietary flavonoid quercetin possess potent antithrombotic activity, and interact with aspirin to enhance antiplatelet effects
AR Stainer, P Sasikumar, AP Bye, AJ Unsworth, LM Holbrook, M Tindall, ...
Th Open 3 (03), e244-e258, 2019
642019
Pharmacological actions of nobiletin in the modulation of platelet function
S Vaiyapuri, H Roweth, MS Ali, AJ Unsworth, AR Stainer, GD Flora, ...
British journal of pharmacology 172 (16), 4133-4145, 2015
642015
Non-genomic effects of nuclear receptors: insights from the anucleate platelet
AJ Unsworth, GD Flora, JM Gibbins
Cardiovascular research 114 (5), 645-655, 2018
592018
Prevalence and prognostic significance of DNMT3A-and TET2-clonal haematopoiesis-driver mutations in patients presenting with ST-segment elevation myocardial infarction
S Wang, S Hu, X Luo, X Bao, J Li, M Liu, Y Lv, C Zhao, M Zeng, X Chen, ...
EBioMedicine 78, 2022
472022
Human platelet protein ubiquitylation and changes following GPVI activation
AJ Unsworth, I Bombik, A Pinto-Fernandez, JF McGouran, R Konietzny, ...
Thrombosis and haemostasis 119 (01), 104-116, 2019
382019
RXR ligands negatively regulate thrombosis and hemostasis
AJ Unsworth, GD Flora, P Sasikumar, AP Bye, T Sage, N Kriek, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (5), 812-822, 2017
382017
Optimizing platelet GPVI inhibition versus haemostatic impairment by the Btk inhibitors ibrutinib, acalabrutinib, ONO/GS-4059, BGB-3111 and evobrutinib
V Denzinger, K Busygina, J Jamasbi, I Pekrul, M Spannagl, C Weber, ...
Thrombosis and Haemostasis 119 (03), 397-406, 2019
362019
Submaximal inhibition of protein kinase C restores ADP-induced dense granule secretion in platelets in the presence of Ca2+
AJ Unsworth, H Smith, P Gissen, SP Watson, CJ Pears
Journal of Biological Chemistry 286 (24), 21073-21082, 2011
342011
Farnesoid X receptor and its ligands inhibit the function of platelets
LA Moraes, AJ Unsworth, S Vaiyapuri, MS Ali, P Sasikumar, T Sage, ...
Arteriosclerosis, thrombosis, and vascular biology 36 (12), 2324-2333, 2016
332016
EphB2 regulates contact-dependent and contact-independent signaling to control platelet function
S Vaiyapuri, T Sage, RH Rana, MP Schenk, MS Ali, AJ Unsworth, ...
Blood, The Journal of the American Society of Hematology 125 (4), 720-730, 2015
332015
PPARγ agonists negatively regulate αIIbβ3 integrin outside‐in signaling and platelet function through up‐regulation of protein kinase A activity
AJ Unsworth, N Kriek, AP Bye, K Naran, T Sage, GD Flora, JM Gibbins
Journal of Thrombosis and Haemostasis 15 (2), 356-369, 2017
312017
The chaperone protein HSP47: a platelet collagen binding protein that contributes to thrombosis and hemostasis
P Sasikumar, KS AlOuda, WJ Kaiser, LM Holbrook, N Kriek, AJ Unsworth, ...
Journal of Thrombosis and Haemostasis 16 (5), 946-959, 2018
282018
The direct thrombin inhibitors dabigatran and lepirudin inhibit GPIbα-mediated platelet aggregation
K Trabold, S Makhoul, S Gambaryan, J van Ryn, U Walter, K Jurk
Thrombosis and haemostasis 119 (06), 916-929, 2019
262019
Multiparameter phenotyping of platelet reactivity for stratification of human cohorts
JL Dunster, AP Bye, N Kriek, T Sage, JL Mitchell, C Kempster, J Batista, ...
Blood advances 5 (20), 4017-4030, 2021
252021
Case Study: Using H5P to design and deliver interactive laboratory practicals
AJ Unsworth, MG Posner
Essays in Biochemistry 66 (1), 19-27, 2022
232022
Overcoming ABCG2-mediated drug resistance with imidazo-[1, 2-b]-pyridazine-based Pim1 kinase inhibitors
RAJ Darby, A Unsworth, S Knapp, ID Kerr, R Callaghan
Cancer chemotherapy and pharmacology 76, 853-864, 2015
232015
Farnesoid X receptor and liver X receptor ligands initiate formation of coated platelets
AJ Unsworth, AP Bye, DS Tannetta, MJR Desborough, N Kriek, T Sage, ...
Arteriosclerosis, thrombosis, and vascular biology 37 (8), 1482-1493, 2017
212017
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