| SAMTOR is an S-adenosylmethionine sensor for the mTORC1 pathway X Gu, JM Orozco, RA Saxton, KJ Condon, GY Liu, PA Krawczyk, ... Science 358 (6364), 813-818, 2017 | 535 | 2017 |
| A Wnt-producing niche drives proliferative potential and progression in lung adenocarcinoma T Tammela, FJ Sanchez-Rivera, NM Cetinbas, K Wu, NS Joshi, ... Nature 545 (7654), 355-359, 2017 | 340 | 2017 |
| KICSTOR recruits GATOR1 to the lysosome and is necessary for nutrients to regulate mTORC1 RL Wolfson, L Chantranupong, GA Wyant, X Gu, JM Orozco, K Shen, ... Nature 543 (7645), 438-442, 2017 | 331 | 2017 |
| Structural basis for the docking of mTORC1 on the lysosomal surface KB Rogala, X Gu, JF Kedir, M Abu-Remaileh, LF Bianchi, AMS Bottino, ... Science 366 (6464), 468-475, 2019 | 166 | 2019 |
| Arg-78 of Nprl2 catalyzes GATOR1-stimulated GTP hydrolysis by the Rag GTPases K Shen, ML Valenstein, X Gu, DM Sabatini Journal of Biological Chemistry 294 (8), 2970-5944, 2019 | 69 | 2019 |
| Structure of the nutrient-sensing hub GATOR2 ML Valenstein, KB Rogala, PV Lalgudi, EJ Brignole, X Gu, RA Saxton, ... Nature 607 (7919), 610-616, 2022 | 54 | 2022 |
| The midnolin-proteasome pathway catches proteins for ubiquitination-independent degradation X Gu, C Nardone, N Kamitaki, A Mao, SJ Elledge, ME Greenberg Science 381 (6660), eadh5021, 2023 | 52 | 2023 |
| The lamin-A/C–LAP2α–BAF1 protein complex regulates mitotic spindle assembly and positioning R Qi, N Xu, G Wang, H Ren, S Li, J Lei, Q Lin, L Wang, X Gu, H Zhang, ... Journal of cell science 128 (15), 2830-2841, 2015 | 41 | 2015 |
| Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila X Gu, P Jouandin, PV Lalgudi, R Binari, ML Valenstein, MA Reid, ... Nature 608 (7921), 209-216, 2022 | 38 | 2022 |
| A central role for regulated protein stability in the control of TFE3 and MITF by nutrients C Nardone, BA Palanski, DC Scott, RT Timms, KW Barber, X Gu, A Mao, ... Molecular cell 83 (1), 57-73. e9, 2023 | 25 | 2023 |
| Author Correction: Sestrin mediates detection of and adaptation to low-leucine diets in Drosophila X Gu, P Jouandin, PV Lalgudi, R Binari, ML Valenstein, MA Reid, ... Nature 609 (7929), E11, 2022 | 1 | 2022 |
| Rag–Ragulator is the central organizer of the physical architecture of the mTORC1 nutrient-sensing pathway ML Valenstein, PV Lalgudi, X Gu, JF Kedir, MS Taylor, RR Chivukula, ... Proceedings of the National Academy of Sciences 121 (35), e2322755121, 2024 | | 2024 |
| Structure of the TXNL1-bound proteasome J Gao, C Nardone, MCJ Yip, H Chino, X Gu, Z Mirman, MJ Rale, JA Paulo, ... bioRxiv, 2024.11. 08.622741, 2024 | | 2024 |
| The Rag GTPases-mTORC1-TFE3 Axis in Kidney Cancer and Neurodevelopment: A Mini Review C Nardone, X Gu, SJ Elledge | | 2023 |
| Methods of identifying modulators of SAMTOR-GATOR1 interaction and use of same to modulate mTORC1 DM Sabatini, X Gu, JM Orozco US Patent 11,499,981, 2022 | | 2022 |
| Nanoscale Insights into the Mechanisms of Cellular Growth and Proliferation KB Rogala, X Gu, JF Kedir, M Abu-Remaileh, LF Bianchi, AMS Bottino, ... Biological, Medical Devices, and Systems, 19, 0 | | |