METTL14 inhibits hematopoietic stem/progenitor differentiation and promotes leukemogenesis via mRNA m6A modification H Weng, H Huang, H Wu, X Qin, BS Zhao, L Dong, H Shi, J Skibbe, ... Cell stem cell 22 (2), 191-205. e9, 2018 | 888 | 2018 |
Histone H3 trimethylation at lysine 36 guides m6A RNA modification co-transcriptionally H Huang, H Weng, K Zhou, T Wu, BS Zhao, M Sun, Z Chen, X Deng, ... Nature 567 (7748), 414-419, 2019 | 584 | 2019 |
Targeting FTO Suppresses Cancer Stem Cell Maintenance and Immune Evasion R Su, L Dong, Y Li, M Gao, L Han, M Wunderlich, X Deng, H Li, Y Huang, ... Cancer Cell, 2020 | 583 | 2020 |
RNA Demethylase ALKBH5 Selectively Promotes Tumorigenesis and Cancer Stem Cell Self-Renewal in Acute Myeloid Leukemia C Shen, Y Sheng, AC Zhu, S Robinson, X Jiang, L Dong, H Chen, R Su, ... Cell Stem Cell, 2020 | 321 | 2020 |
R-2-hydroxyglutarate attenuates aerobic glycolysis in leukemia by targeting the FTO/m6A/PFKP/LDHB axis Y Qing, L Dong, L Gao, C Li, Y Li, L Han, E Prince, B Tan, X Deng, ... Molecular Cell 81 (5), 922-939, 2021 | 244 | 2021 |
METTL16 exerts an m6A-independent function to facilitate translation and tumorigenesis R Su, L Dong, Y Li, M Gao, PC He, W Liu, J Wei, Z Zhao, L Gao, L Han, ... Nature cell biology 24 (2), 205-216, 2022 | 225 | 2022 |
MicroRNA-29a and microRNA-142-3p are regulators of myeloid differentiation and acute myeloid leukemia XS Wang, JN Gong, J Yu, F Wang, XH Zhang, XL Yin, ZQ Tan, ZM Luo, ... Blood, The Journal of the American Society of Hematology 119 (21), 4992-5004, 2012 | 220 | 2012 |
MiR-181 family: regulators of myeloid differentiation and acute myeloid leukemia as well as potential therapeutic targets R Su, HS Lin, XH Zhang, XL Yin, HM Ning, B Liu, PF Zhai, JN Gong, ... Oncogene 34 (25), 3226-3239, 2015 | 183 | 2015 |
The role, mechanism and potentially therapeutic application of microRNA-29 family in acute myeloid leukemia JN Gong, J Yu, HS Lin, XH Zhang, XL Yin, Z Xiao, F Wang, XS Wang, ... Cell Death & Differentiation 21 (1), 100-112, 2014 | 129 | 2014 |
PU. 1-regulated long noncoding RNA lnc-MC controls human monocyte/macrophage differentiation through interaction with microRNA 199a-5p MT Chen, HS Lin, C Shen, YN Ma, F Wang, HL Zhao, J Yu, JW Zhang Molecular and cellular biology, 2015 | 123 | 2015 |
METTL16 drives leukemogenesis and leukemia stem cell self-renewal by reprogramming BCAA metabolism L Han, L Dong, K Leung, Z Zhao, Y Li, L Gao, Z Chen, J Xue, Y Qing, W Li, ... Cell Stem Cell 30 (1), 52-68. e13, 2023 | 75 | 2023 |
The PU. 1-modulated microRNA-22 is a regulator of monocyte/macrophage differentiation and acute myeloid leukemia C Shen, MT Chen, XH Zhang, XL Yin, HM Ning, R Su, HS Lin, L Song, ... PLoS genetics 12 (9), e1006259, 2016 | 67 | 2016 |
Targeted inhibition of STAT/TET1 axis as a therapeutic strategy for acute myeloid leukemia X Jiang, C Hu, K Ferchen, J Nie, X Cui, CH Chen, L Cheng, Z Zuo, ... Nature communications 8 (1), 2099, 2017 | 60 | 2017 |
Homoharringtonine exhibits potent anti-tumor effect and modulates DNA epigenome in acute myeloid leukemia by targeting SP1/TET1/5hmC C Li, L Dong, R Su, Y Bi, Y Qing, X Deng, Y Zhou, C Hu, M Yu, H Huang, ... haematologica 105 (1), 148-160, 2020 | 56 | 2020 |
ZFP36L1 promotes monocyte/macrophage differentiation by repressing CDK6 MT Chen, L Dong, XH Zhang, XL Yin, HM Ning, C Shen, R Su, F Li, ... Scientific reports 5 (1), 16229, 2015 | 55 | 2015 |
miR-199a-5p inhibits monocyte/macrophage differentiation by targeting the activin A type 1B receptor gene and finally reducing C/EBPα expression HS Lin, JN Gong, R Su, MT Chen, L Song, C Shen, F Wang, YN Ma, ... Journal of leukocyte biology 96 (6), 1023-1035, 2014 | 49 | 2014 |
RBFOX2 recognizes N6-methyladenosine to suppress transcription and block myeloid leukaemia differentiation X Dou, Y Xiao, C Shen, K Wang, T Wu, C Liu, Y Li, X Yu, J Liu, Q Dai, ... Nature cell biology 25 (9), 1359-1368, 2023 | 38 | 2023 |
DNA N6-methyldeoxyadenosine in mammals and human disease C Shen, K Wang, X Deng, J Chen Trends in Genetics, 2022 | 35 | 2022 |
c-Myc suppresses miR-451⊣ YWTAZ/AKT axis via recruiting HDAC3 in acute myeloid leukemia R Su, JN Gong, MT Chen, L Song, C Shen, XH Zhang, XL Yin, HM Ning, ... Oncotarget 7 (47), 77430, 2016 | 32 | 2016 |
RNA m6A reader YTHDF2 facilitates precursor miR-126 maturation to promote acute myeloid leukemia progression Z Zhang, K Zhou, L Han, A Small, J Xue, H Huang, H Weng, R Su, B Tan, ... Genes & Diseases 11 (1), 382-396, 2024 | 20 | 2024 |