| Dendritic structural plasticity and neuropsychiatric disease MP Forrest, E Parnell, P Penzes Nature Reviews Neuroscience 19 (4), 215-234, 2018 | 468 | 2018 |
| The future of EPAC-targeted therapies: agonism versus antagonism E Parnell, TM Palmer, SJ Yarwood Trends in pharmacological sciences 36 (4), 203-214, 2015 | 96 | 2015 |
| Regulation of the inflammatory response of vascular endothelial cells by EPAC1 E Parnell, BO Smith, TM Palmer, A Terrin, M Zaccolo, SJ Yarwood British journal of pharmacology 166 (2), 434-446, 2012 | 79 | 2012 |
| Partial loss of USP9X function leads to a male neurodevelopmental and behavioral disorder converging on transforming growth factor β signaling BV Johnson, R Kumar, S Oishi, S Alexander, M Kasherman, MS Vega, ... Biological psychiatry 87 (2), 100-112, 2020 | 57 | 2020 |
| Usp9X controls ankyrin-repeat domain protein homeostasis during dendritic spine development S Yoon, E Parnell, M Kasherman, MP Forrest, K Myczek, S Premarathne, ... Neuron 105 (3), 506-521. e7, 2020 | 47 | 2020 |
| The cAMP sensors, EPAC1 and EPAC2, display distinct subcellular distributions despite sharing a common nuclear pore localisation signal E Parnell, BO Smith, SJ Yarwood Cellular signalling 27 (5), 989-996, 2015 | 43 | 2015 |
| Identification of a novel, small molecule partial agonist for the cyclic AMP sensor, EPAC1 E Parnell, SP McElroy, J Wiejak, GL Baillie, A Porter, DR Adams, ... Scientific reports 7 (1), 294, 2017 | 36 | 2017 |
| KALRN: A central regulator of synaptic function and synaptopathies E Parnell, LP Shapiro, RA Voorn, MP Forrest, HA Jalloul, DD Loizzo, ... Gene 768, 145306, 2021 | 33 | 2021 |
| Shed CNTNAP2 ectodomain is detectable in CSF and regulates Ca2+ homeostasis and network synchrony via PMCA2/ATP2B2 MD Martín-de-Saavedra, M Dos Santos, L Culotta, O Varea, BP Spielman, ... Neuron 110 (4), 627-643. e9, 2022 | 28 | 2022 |
| Missense variant contribution to USP9X-female syndrome LA Jolly, E Parnell, AE Gardner, MA Corbett, LA Pérez-Jurado, M Shaw, ... NPJ Genomic Medicine 5 (1), 53, 2020 | 27 | 2020 |
| Phosphorylation of ezrin on Thr567 is required for the synergistic activation of cell spreading by EPAC1 and protein kinase A in HEK293T cells E Parnell, A Koschinski, M Zaccolo, RT Cameron, GS Baillie, GL Baillie, ... Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1853 (7), 1749-1758, 2015 | 26 | 2015 |
| TGF-β-induced phosphorylation of Usp9X stabilizes ankyrin-G and regulates dendritic spine development and maintenance S Yoon, E Parnell, P Penzes Cell reports 31 (8), 2020 | 20 | 2020 |
| The potential of a novel class of EPAC-selective agonists to combat cardiovascular inflammation G Barker, E Parnell, B Van Basten, H Buist, DR Adams, SJ Yarwood Journal of Cardiovascular Development and Disease 4 (4), 22, 2017 | 19 | 2017 |
| Excitatory dysfunction drives network and calcium handling deficits in 16p11. 2 duplication schizophrenia induced pluripotent stem cell–derived neurons E Parnell, L Culotta, MP Forrest, HA Jalloul, BL Eckman, DD Loizzo, ... Biological psychiatry 94 (2), 153-163, 2023 | 18 | 2023 |
| Interactions between Epac1 and ezrin in the control of endothelial barrier function E Parnell, SJ Yarwood Biochemical Society Transactions 42 (2), 274-278, 2014 | 16 | 2014 |
| Identification of a novel class of benzofuran oxoacetic acid-derived ligands that selectively activate cellular EPAC1 E M. Beck, E Parnell, A Cowley, A Porter, J Gillespie, J Robinson, ... Cells 8 (11), 1425, 2019 | 15 | 2019 |
| The cyclic AMP phosphodiesterase 4D5 (PDE4D5)/receptor for activated C-kinase 1 (RACK1) signalling complex as a sensor of the extracellular nano-environment SJ Yarwood, E Parnell, RJ Bird Cellular Signalling 35, 282-289, 2017 | 12 | 2017 |
| A developmental delay linked missense mutation in Kalirin-7 disrupts protein function and neuronal morphology E Parnell, RA Voorn, MD Martin-de-Saavedra, DD Loizzo, M Dos Santos, ... Frontiers in Molecular Neuroscience 15, 994513, 2022 | 1 | 2022 |
| Pro-cognitive reshaping of neuronal dynamics by a human CSF-based factor M Dos Santos, MP Forrest, EK Bomba-Warczak, E Parnell, SL Edassery, ... bioRxiv, 2024.12. 26.629959, 2024 | | 2024 |
| Tunneling nanotubes at the microglia‐neuron interface in neuroinflammation and Alzheimer’s disease CR Zaccard, E Parnell, I Gippo, C Geula, P Penzes Alzheimer's & Dementia 19, e076872, 2023 | | 2023 |