| Trp53R172H and KrasG12D cooperate to promote chromosomal instability and widely metastatic pancreatic ductal adenocarcinoma in mice SR Hingorani, L Wang, AS Multani, C Combs, TB Deramaudt, RH Hruban, ... Cancer cell 7 (5), 469-483, 2005 | 2886 | 2005 |
| Longevity, stress response, and cancer in aging telomerase-deficient mice KL Rudolph, S Chang, HW Lee, M Blasco, GJ Gottlieb, C Greider, ... Cell 96 (5), 701-712, 1999 | 1672 | 1999 |
| Telomere dysfunction promotes non-reciprocal translocations and epithelial cancers in mice SE Artandi, S Chang, SL Lee, S Alson, GJ Gottlieb, L Chin, RA DePinho Nature 406 (6796), 641-645, 2000 | 1381 | 2000 |
| Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects DA Tuveson, AT Shaw, NA Willis, DP Silver, EL Jackson, S Chang, ... Cancer cell 5 (4), 375-387, 2004 | 956 | 2004 |
| Essential role of limiting telomeres in the pathogenesis of Werner syndrome S Chang, AS Multani, NG Cabrera, ML Naylor, P Laud, D Lombard, ... Nature genetics 36 (8), 877-882, 2004 | 538 | 2004 |
| Inhibition of experimental liver cirrhosis in mice by telomerase gene delivery KL Rudolph, S Chang, M Millard, N Schreiber-Agus, RA DePinho Science 287 (5456), 1253-1258, 2000 | 533 | 2000 |
| Pot1 deficiency initiates DNA damage checkpoint activation and aberrant homologous recombination at telomeres L Wu, AS Multani, H He, W Cosme-Blanco, Y Deng, JM Deng, O Bachilo, ... Cell 126 (1), 49-62, 2006 | 532 | 2006 |
| Telomere dysfunction and tumour suppression: the senescence connection Y Deng, SS Chan, S Chang Nature reviews cancer 8 (6), 450-458, 2008 | 505 | 2008 |
| The nonhomologous end-joining pathway of DNA repair is required for genomic stability and the suppression of translocations DO Ferguson, JAM Sekiguchi, S Chang, KM Frank, Y Gao, RA DePinho, ... Proceedings of the National Academy of Sciences 97 (12), 6630-6633, 2000 | 490 | 2000 |
| Conformal deformation of metrics on SYA Chang, PC Yang Journal of differential geometry 27 (2), 259-296, 1988 | 458 | 1988 |
| TERRA and hnRNPA1 orchestrate an RPA-to-POT1 switch on telomeric single-stranded DNA RL Flynn, RC Centore, RJ O’Sullivan, R Rai, A Tse, Z Songyang, S Chang, ... Nature 471 (7339), 532-536, 2011 | 421 | 2011 |
| IEEE Electron Dev CY Chen, YK Su, SJ Chang, GC Chi, JK Sheu, JF Chen, CH Liu, UH Liaw Lett 22 (7), 321, 2001 | 408 | 2001 |
| Mre11 nuclease activity has essential roles in DNA repair and genomic stability distinct from ATM activation J Buis, Y Wu, Y Deng, J Leddon, G Westfield, M Eckersdorff, ... Cell 135 (1), 85-96, 2008 | 391 | 2008 |
| Some weighted norm inequalities concerning the Schrödinger operators SYA Chang, JM Wilson, TH Wolff Commentarii Mathematici Helvetici 60, 217-246, 1985 | 387 | 1985 |
| Telomere dysfunction impairs DNA repair and enhances sensitivity to ionizing radiation KK Wong, S Chang, SR Weiler, S Ganesan, J Chaudhuri, C Zhu, ... Nature genetics 26 (1), 85-88, 2000 | 375 | 2000 |
| Chromosome stability, in the absence of apoptosis, is critical for suppression of tumorigenesis in Trp53 mutant mice G Liu, JM Parant, G Lang, P Chau, A Chavez-Reyes, AK El-Naggar, ... Nature genetics 36 (1), 63-68, 2004 | 374 | 2004 |
| WRN helicase is a synthetic lethal target in microsatellite unstable cancers EM Chan, T Shibue, JM McFarland, B Gaeta, M Ghandi, N Dumont, ... Nature 568 (7753), 551-556, 2019 | 335 | 2019 |
| Dysfunctional telomeres activate an ATM‐ATR‐dependent DNA damage response to suppress tumorigenesis X Guo, Y Deng, Y Lin, W Cosme‐Blanco, S Chan, H He, G Yuan, ... The EMBO journal 26 (22), 4709-4719, 2007 | 320 | 2007 |
| Telomere dysfunction provokes regional amplification and deletion in cancer genomes RC O'Hagan, S Chang, RS Maser, R Mohan, SE Artandi, L Chin, ... Cancer cell 2 (2), 149-155, 2002 | 306 | 2002 |
| Telomere dysfunction suppresses spontaneous tumorigenesis in vivo by initiating p53‐dependent cellular senescence W Cosme‐Blanco, MF Shen, AJF Lazar, S Pathak, G Lozano, AS Multani, ... EMBO reports 8 (5), 497-503, 2007 | 264 | 2007 |
