| The recent progress of isoxazole in medicinal chemistry J Zhu, J Mo, H Lin, Y Chen, H Sun Bioorganic & Medicinal Chemistry 26 (12), 3065-3075, 2018 | 367 | 2018 |
| Recent progress in the identification of selective butyrylcholinesterase inhibitors for Alzheimer's disease Q Li, H Yang, Y Chen, H Sun European journal of medicinal chemistry 132, 294-309, 2017 | 308 | 2017 |
| Degradation of proteins by PROTACs and other strategies Y Wang, X Jiang, F Feng, W Liu, H Sun Acta Pharmaceutica Sinica B 10 (2), 207-238, 2020 | 270 | 2020 |
| Rational design of multitarget-directed ligands: strategies and emerging paradigms J Zhou, X Jiang, S He, H Jiang, F Feng, W Liu, W Qu, H Sun Journal of medicinal chemistry 62 (20), 8881-8914, 2019 | 265 | 2019 |
| Discovery of potent Keap1–Nrf2 protein–protein interaction inhibitor based on molecular binding determinants analysis ZY Jiang, MC Lu, LL Xu, TT Yang, MY Xi, XL Xu, XK Guo, XJ Zhang, ... Journal of medicinal chemistry 57 (6), 2736-2745, 2014 | 241 | 2014 |
| Donepezil-based multi-functional cholinesterase inhibitors for treatment of Alzheimer's disease Q Li, S He, Y Chen, F Feng, W Qu, H Sun European journal of medicinal chemistry 158, 463-477, 2018 | 198 | 2018 |
| Strategies for structural modification of small molecules to improve blood–brain barrier penetration: a recent perspective B Xiong, Y Wang, Y Chen, S Xing, Q Liao, Y Chen, Q Li, W Li, H Sun Journal of Medicinal Chemistry 64 (18), 13152-13173, 2021 | 136 | 2021 |
| NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction C Zhang, HJ Wang, QC Bao, L Wang, TK Guo, WL Chen, LL Xu, HS Zhou, ... Oncotarget 7 (45), 73593, 2016 | 134 | 2016 |
| Dual GSK-3β/AChE inhibitors as a new strategy for multitargeting anti-Alzheimer’s disease drug discovery XY Jiang, TK Chen, JT Zhou, SY He, HY Yang, Y Chen, W Qu, F Feng, ... ACS medicinal chemistry letters 9 (3), 171-176, 2018 | 101 | 2018 |
| Structure–activity and structure–property relationship and exploratory in vivo evaluation of the nanomolar Keap1–Nrf2 protein–protein interaction inhibitor ZY Jiang, LL Xu, MC Lu, ZY Chen, ZW Yuan, XL Xu, XK Guo, XJ Zhang, ... Journal of medicinal chemistry 58 (16), 6410-6421, 2015 | 100 | 2015 |
| Peptide-based and small synthetic molecule inhibitors on PD-1/PD-L1 pathway: A new choice for immunotherapy? T Chen, Q Li, Z Liu, Y Chen, F Feng, H Sun European Journal of Medicinal Chemistry 161, 378-398, 2019 | 86 | 2019 |
| Overview of AKR1C3: inhibitor achievements and disease insights Y Liu, S He, Y Chen, Y Liu, F Feng, W Liu, Q Guo, L Zhao, H Sun Journal of medicinal chemistry 63 (20), 11305-11329, 2020 | 84 | 2020 |
| Discovery of new acetylcholinesterase and butyrylcholinesterase inhibitors through structure-based virtual screening Y Chen, H Lin, H Yang, R Tan, Y Bian, T Fu, W Li, L Wu, Y Pei, H Sun RSC advances 7 (6), 3429-3438, 2017 | 84 | 2017 |
| Structure and therapeutic uses of butyrylcholinesterase: Application in detoxification, Alzheimer's disease, and fat metabolism S Xing, Q Li, B Xiong, Y Chen, F Feng, W Liu, H Sun Medicinal Research Reviews 41 (2), 858-901, 2021 | 83 | 2021 |
| Recent research progress of Uncaria spp. based on alkaloids: phytochemistry, pharmacology and structural chemistry N Qin, X Lu, Y Liu, Y Qiao, W Qu, F Feng, H Sun European Journal of Medicinal Chemistry 210, 112960, 2021 | 74 | 2021 |
| Target the human alanine/serine/cysteine transporter 2 (ASCT2): achievement and future for novel cancer therapy H Jiang, N Zhang, T Tang, F Feng, H Sun, W Qu Pharmacological Research 158, 104844, 2020 | 72 | 2020 |
| Discovery and biological evaluation of a novel highly potent selective butyrylcholinsterase inhibitor Q Li, S Xing, Y Chen, Q Liao, B Xiong, S He, W Lu, Y Liu, H Yang, Q Li, ... Journal of Medicinal Chemistry 63 (17), 10030-10044, 2020 | 70 | 2020 |
| Therapeutic potential of targeting SHP2 in human developmental disorders and cancers D Shen, W Chen, J Zhu, G Wu, R Shen, M Xi, H Sun European Journal of Medicinal Chemistry 190, 112117, 2020 | 70 | 2020 |
| Novel protein–protein interaction inhibitor of Nrf2–Keap1 discovered by structure-based virtual screening HP Sun, ZY Jiang, MY Zhang, MC Lu, TT Yang, Y Pan, HZ Huang, ... MedChemComm 5 (1), 93-98, 2014 | 69 | 2014 |
| Synthesis, pharmacology and molecular docking on multifunctional tacrine-ferulic acid hybrids as cholinesterase inhibitors against Alzheimer’s disease J Zhu, H Yang, Y Chen, H Lin, Q Li, J Mo, Y Bian, Y Pei, H Sun Journal of enzyme inhibition and medicinal chemistry 33 (1), 496-506, 2018 | 68 | 2018 |