The presence and severity of chronic kidney disease predicts all-cause mortality in type 1 diabetes PH Groop, MC Thomas, JL Moran, J Waden, LM Thorn, VP Mäkinen, ... Diabetes 58 (7), 1651-1658, 2009 | 759 | 2009 |
Metabolic signatures of insulin resistance in 7,098 young adults P Würtz, VP Mäkinen, P Soininen, AJ Kangas, T Tukiainen, J Kettunen, ... Diabetes 61 (6), 1372-1380, 2012 | 347 | 2012 |
New susceptibility loci associated with kidney disease in type 1 diabetes N Sandholm, RM Salem, AJ McKnight, EP Brennan, C Forsblom, ... Public Library of Science 8 (9), e1002921, 2012 | 283 | 2012 |
Long-term leisure-time physical activity and serum metabolome UM Kujala, VP Mäkinen, I Heinonen, P Soininen, AJ Kangas, ... Circulation 127 (3), 340-348, 2013 | 257 | 2013 |
Circulating metabolite predictors of glycemia in middle-aged men and women P Würtz, M Tiainen, VP Mäkinen, AJ Kangas, P Soininen, J Saltevo, ... Diabetes care 35 (8), 1749-1756, 2012 | 242 | 2012 |
Structural and theoretical basis for ligand exchange on thiolate monolayer protected gold nanoclusters CL Heinecke, TW Ni, S Malola, V Makinen, OA Wong, H Hakkinen, ... Journal of the American Chemical Society 134 (32), 13316-13322, 2012 | 241 | 2012 |
Integrative genomics reveals novel molecular pathways and gene networks for coronary artery disease VP Mäkinen, M Civelek, Q Meng, B Zhang, J Zhu, C Levian, T Huan, ... PLoS genetics 10 (7), e1004502, 2014 | 229 | 2014 |
1H NMR metabonomics approach to the disease continuum of diabetic complications and premature death VP Mäkinen, P Soininen, C Forsblom, M Parkkonen, P Ingman, K Kaski, ... Molecular systems biology 4 (1), 167, 2008 | 210 | 2008 |
Metabolic profiling of pregnancy: cross-sectional and longitudinal evidence Q Wang, P Würtz, K Auro, VP Mäkinen, AJ Kangas, P Soininen, M Tiainen, ... BMC medicine 14, 1-14, 2016 | 194 | 2016 |
Discovery of early-stage biomarkers for diabetic kidney disease using ms-based metabolomics (FinnDiane study) FM Van der Kloet, FWA Tempels, N Ismail, R Van der Heijden, PT Kasper, ... Metabolomics 8, 109-119, 2012 | 190 | 2012 |
Ligand-Stabilized Au13Cux (x = 2, 4, 8) Bimetallic Nanoclusters: Ligand Engineering to Control the Exposure of Metal Sites H Yang, Y Wang, J Lei, L Shi, X Wu, V Mäkinen, S Lin, Z Tang, J He, ... Journal of the American Chemical Society 135 (26), 9568-9571, 2013 | 176 | 2013 |
A multi-metabolite analysis of serum by 1H NMR spectroscopy: early systemic signs of Alzheimer’s disease T Tukiainen, T Tynkkynen, VP Mäkinen, P Jylänki, A Kangas, J Hokkanen, ... Biochemical and biophysical research communications 375 (3), 356-361, 2008 | 143 | 2008 |
Effects of Silver Doping on the Geometric and Electronic Structure and Optical Absorption Spectra of the Au25–nAgn(SH)18– (n = 1, 2, 4, 6, 8, 10, 12 … EB Guidez, V Makinen, H Hakkinen, CM Aikens The Journal of Physical Chemistry C 116 (38), 20617-20624, 2012 | 123 | 2012 |
Identification and validation of N-acetyltransferase 2 as an insulin sensitivity gene JW Knowles, W Xie, Z Zhang, I Chennemsetty, TL Assimes, J Paananen, ... The Journal of clinical investigation 125 (4), 1739-1751, 2015 | 122 | 2015 |
Mergeomics: multidimensional data integration to identify pathogenic perturbations to biological systems L Shu, Y Zhao, Z Kurt, SG Byars, T Tukiainen, J Kettunen, LD Orozco, ... BMC genomics 17, 1-16, 2016 | 121 | 2016 |
Metabolic phenotypes, vascular complications, and premature deaths in a population of 4,197 patients with type 1 diabetes VP Makinen, C Forsblom, LM Thorn, J Wadén, D Gordin, O Heikkila, ... Diabetes 57 (9), 2480-2487, 2008 | 121 | 2008 |
Lipid abnormalities predict progression of renal disease in patients with type 1 diabetes N Tolonen, C Forsblom, L Thorn, J Wadén, M Rosengård-Bärlund, ... Diabetologia 52, 2522-2530, 2009 | 113 | 2009 |
Metabolic profiling of polycystic ovary syndrome reveals interactions with abdominal obesity A Couto Alves, B Valcarcel, VP Mäkinen, L Morin-Papunen, S Sebert, ... International Journal of Obesity 41 (9), 1331-1340, 2017 | 110 | 2017 |
Diagnosing diabetic nephropathy by 1H NMR metabonomics of serum VP Mäkinen, P Soininen, C Forsblom, M Parkkonen, P Ingman, K Kaski, ... Magnetic Resonance Materials in Physics, Biology and Medicine 19, 281-296, 2006 | 106 | 2006 |
Soluble receptor for AGE (RAGE) is a novel independent predictor of all-cause and cardiovascular mortality in type 1 diabetes MC Thomas, J Söderlund, M Lehto, VP Mäkinen, JL Moran, ME Cooper, ... Diabetologia 54, 2669-2677, 2011 | 99 | 2011 |