フォロー
Parag Patwardhan
Parag Patwardhan
Senior Research Scientist, Memorial Sloan Kettering Cancer Center
確認したメール アドレス: mskcc.org
タイトル
引用先
引用先
Myristoylation and membrane binding regulate c-Src stability and kinase activity
P Patwardhan, MD Resh
Molecular and cellular biology 30 (17), 4094-4107, 2010
2072010
Processive phosphorylation: mechanism and biological importance
P Patwardhan, WT Miller
Cellular signalling 19 (11), 2218-2226, 2007
1322007
Sustained inhibition of receptor tyrosine kinases and macrophage depletion by PLX3397 and rapamycin as a potential new approach for the treatment of MPNSTs
PP Patwardhan, O Surriga, MJ Beckman, E de Stanchina, RP Dematteo, ...
Clinical cancer research 20 (12), 3146-3158, 2014
1232014
MLN0128, an ATP-Competitive mTOR Kinase Inhibitor with Potent In Vitro and In Vivo Antitumor Activity, as Potential Therapy for Bone and Soft-Tissue Sarcoma
EK Slotkin, PP Patwardhan, SD Vasudeva, E de Stanchina, WD Tap, ...
Molecular cancer therapeutics 14 (2), 395-406, 2015
1122015
Significant blockade of multiple receptor tyrosine kinases by MGCD516 (Sitravatinib), a novel small molecule inhibitor, shows potent anti-tumor activity in preclinical models …
PP Patwardhan, KS Ivy, E Musi, E de Stanchina, GK Schwartz
Oncotarget 7 (4), 4093, 2015
1022015
Individual Cas phosphorylation sites are dispensable for processive phosphorylation by Src and anchorage-independent cell growth
P Patwardhan, Y Shen, GS Goldberg, WT Miller
Journal of Biological Chemistry 281 (30), 20689-20697, 2006
482006
Targeted inhibition of glutaminase as a potential new approach for the treatment of NF1 associated soft tissue malignancies
TN Sheikh, PP Patwardhan, S Cremers, GK Schwartz
Oncotarget 8 (55), 94054, 2017
302017
Preclinical evaluation of nintedanib, a triple angiokinase inhibitor, in soft-tissue sarcoma: potential therapeutic implication for synovial sarcoma
PP Patwardhan, E Musi, GK Schwartz
Molecular Cancer Therapeutics 17 (11), 2329-2340, 2018
152018
Phase 1 combination therapy with pexidartinib (PEX) and sirolimus (S) to target tumor-associated macrophages in pigmented villonodular synovitis, malignant peripheral nerve …
GA Manji, BA Van Tine, SM Lee, A Raufi, P Patwardhan, LE Blumberg, ...
Journal of Clinical Oncology 37 (15_suppl), 11055-11055, 2019
92019
Phase 1/2 study of combination therapy with pexidartinib and sirolimus to target tumor-associated macrophages in malignant peripheral nerve sheath tumors.
GA Manji, P Patwardhan, SM Lee, N Matos, E Bentlyewski, BA Van Tine, ...
Journal of Clinical Oncology 34 (15_suppl), TPS11070-TPS11070, 2016
82016
Combination treatment with SAHA and 5-Azacytidine (Decitabine) induces apoptosis and suppresses tumor growth in preclinical models of chondrosarcoma
T Sheikh, P Patwardhan, GK Schwartz
Cancer Research 77 (13_Supplement), 5066-5066, 2017
42017
Phase 2 trial of the novel multi-receptor tyrosine kinase inhibitor sitravatinib in well-differentiated/dedifferentiated liposarcoma.
M Ingham, SM Lee, P Patwardhan, E Choy, I Chen, S Singh-Kandah, ...
Journal of Clinical Oncology 35 (15_suppl), TPS11082-TPS11082, 2017
42017
Synthesis of functional signaling domains by combinatorial polymerization of phosphorylation motifs
P Patwardhan, K Shiba, C Gordon, BP Craddock, M Tamiko, WT Miller
ACS chemical biology 4 (9), 751-758, 2009
42009
CB839, an orally bioavailable glutaminase inhibitor, shows potent antitumor activity in vitro against models of soft tissue sarcoma and chondrosarcoma
TN Sheikh, PP Patwardhan, S Cremers, GK Schwartz
Cancer Research 75 (15_Supplement), 4450-4450, 2015
32015
Abstract A30: preclinical study of a combination of mocetinostat (HDAC inhibitor) and 5-AZA-dC (decitabine) in chondrosarcoma
TN Sheikh, P Patwardhan, GK Schwartz
Clinical Cancer Research 24 (2_Supplement), A30-A30, 2018
22018
Neurofibromatosis type 1 (NF1) status determines sensitivity of soft tissue sarcoma and melanoma cell lines to glutaminase inhibitors
TN Sheikh, PP Patwardhan, GK Schwartz
Cancer Research 76 (14_Supplement), 19-19, 2016
22016
Preclinical study of a combination of mocetinostat (HDAC inhibitor) and 5-AZA-dC (decitabine) in chondrosarcoma
TN Sheikh, P Patwardhan, GK Schwartz, H Irving
CLINICAL CANCER RESEARCH 24 (2), 51-52, 2018
12018
Preclinical development of a novel multi-targeted kinase inhibitor, MG516, for the treatment of sarcoma
KS Ivy, PP Patwardhan, GK Schwartz
Cancer Research 74 (19_Supplement), 1751-1751, 2014
12014
Abstract PO-052: Combinatorial targeting of chromatin and metabolism for synergistic anti-cancer efficacy
TN Sheikh, X Chen, X Xu, PP Patwardhan, GK Schwartz, C Lu
Cancer Research 80 (23_Supplement), PO-052-PO-052, 2020
2020
Pre-clinical evaluation of CDK4/6 inhibitor resistance and immunologic modification in liposarcoma
E Musi, PP Patwardhan, M Ingham, GK Schwartz
Cancer Research 80 (16_Supplement), 5289-5289, 2020
2020
現在システムで処理を実行できません。しばらくしてからもう一度お試しください。
論文 1–20