AG-221, a First-in-Class Therapy Targeting Acute Myeloid Leukemia Harboring Oncogenic IDH2 Mutations K Yen, J Travins, F Wang, MD David, E Artin, K Straley, A Padyana, ... Cancer discovery 7 (5), 478-493, 2017 | 463 | 2017 |
Review of therapeutic drug monitoring of anticancer drugs part two–targeted therapies N Widmer, C Bardin, E Chatelut, A Paci, J Beijnen, D Levêque, G Veal, ... European journal of cancer 50 (12), 2020-2036, 2014 | 362 | 2014 |
Systemic short chain fatty acids limit antitumor effect of CTLA-4 blockade in hosts with cancer C Coutzac, JM Jouniaux, A Paci, J Schmidt, D Mallardo, A Seck, ... Nature communications 11 (1), 2168, 2020 | 361 | 2020 |
Review of therapeutic drug monitoring of anticancer drugs part 1–cytotoxics A Paci, G Veal, C Bardin, D Levêque, N Widmer, J Beijnen, A Astier, ... European journal of cancer 50 (12), 2010-2019, 2014 | 309 | 2014 |
Crizotinib-induced immunogenic cell death in non-small cell lung cancer P Liu, L Zhao, J Pol, S Levesque, A Petrazzuolo, C Pfirschke, C Engblom, ... Nature communications 10 (1), 1486, 2019 | 267 | 2019 |
Personalizing busulfan-based conditioning: considerations from the american society for blood and marrow transplantation practice guidelines committee J Palmer, JS McCune, MA Perales, D Marks, J Bubalo, M Mohty, ... Biology of Blood and Marrow Transplantation 22 (11), 1915-1925, 2016 | 158 | 2016 |
Vemurafenib in pediatric patients with BRAFV600E mutated high‐grade gliomas F Bautista, A Paci, V Minard‐Colin, C Dufour, J Grill, L Lacroix, P Varlet, ... Pediatric blood & cancer 61 (6), 1101-1103, 2014 | 158 | 2014 |
Therapeutic drug monitoring in cancer–are we missing a trick? C Bardin, G Veal, A Paci, E Chatelut, A Astier, D Levêque, N Widmer, ... European journal of cancer 50 (12), 2005-2009, 2014 | 136 | 2014 |
Human pharmacokinetic study of heated intraperitoneal oxaliplatin in increasingly hypotonic solutions after complete resection of peritoneal carcinomatosis D Elias, A El Otmany, M Bonnay, A Paci, M Ducreux, S Antoun, P Lasser, ... Oncology 63 (4), 346-352, 2002 | 131 | 2002 |
Body composition variation and impact of low skeletal muscle mass in patients with advanced medullary thyroid carcinoma treated with vandetanib: results from a placebo … MH Massicotte, I Borget, S Broutin, VE Baracos, S Leboulleux, E Baudin, ... The Journal of Clinical Endocrinology & Metabolism 98 (6), 2401-2408, 2013 | 127 | 2013 |
Serum detection of nonadherence to adjuvant tamoxifen and breast cancer recurrence risk B Pistilli, A Paci, AR Ferreira, A Di Meglio, V Poinsignon, A Bardet, ... Journal of Clinical Oncology 38 (24), 2762-2772, 2020 | 123 | 2020 |
The IDH2 R172K mutation associated with angioimmunoblastic T-cell lymphoma produces 2HG in T cells and impacts lymphoid development F Lemonnier, RA Cairns, S Inoue, WY Li, A Dupuy, S Broutin, N Martin, ... Proceedings of the National Academy of Sciences 113 (52), 15084-15089, 2016 | 123 | 2016 |
Squalenoylation favorably modifies the in vivo pharmacokinetics and biodistribution of gemcitabine in mice LH Reddy, H Khoury, A Paci, A Deroussent, H Ferreira, C Dubernet, ... Drug Metabolism and Disposition 36 (8), 1570-1577, 2008 | 115 | 2008 |
Oxazaphosphorines: new therapeutic strategies for an old class of drugs B Giraud, G Hebert, A Deroussent, GJ Veal, G Vassal, A Paci Expert opinion on drug metabolism & toxicology 6 (8), 919-938, 2010 | 111 | 2010 |
Mitotane alters mitochondrial respiratory chain activity by inducing cytochrome c oxidase defect in human adrenocortical cells S Hescot, A Slama, A Lombes, A Paci, H Remy, S Leboulleux, ... | 110 | 2014 |
Dihydropyrimidine déhydrogenase (DPD) deficiency screening and securing of fluoropyrimidine-based chemotherapies: Update and recommendations of the French GPCO-Unicancer and … MA Loriot, J Ciccolini, F Thomas, C Barin-Le-Guellec, B Royer, G Milano, ... Bulletin du cancer 105 (4), 397-407, 2018 | 97 | 2018 |
Pharmacokinetic behavior and appraisal of intravenous busulfan dosing in infants and older children: the results of a population pharmacokinetic study from a large pediatric … A Paci, G Vassal, D Moshous, JH Dalle, N Bleyzac, B Neven, ... Therapeutic drug monitoring 34 (2), 198-208, 2012 | 97 | 2012 |
Intestinal bacterial β-glucuronidase as a possible predictive biomarker of irinotecan-induced diarrhea severity AN Chamseddine, M Ducreux, JP Armand, X Paoletti, T Satar, A Paci, ... Pharmacology & therapeutics 199, 1-15, 2019 | 91 | 2019 |
Phase II study of vinorelbine and continuous low doses cyclophosphamide in children and young adults with a relapsed or refractory malignant solid tumour: good tolerance … V Minard-Colin, JL Ichante, L Nguyen, A Paci, D Orbach, C Bergeron, ... European journal of cancer 48 (15), 2409-2416, 2012 | 90 | 2012 |
Liquid chromatography–tandem mass spectrometry assay of reduced and oxidized glutathione and main precursors in mice liver J Bouligand, A Deroussent, A Paci, J Morizet, G Vassal Journal of Chromatography B 832 (1), 67-74, 2006 | 83 | 2006 |