Therapeutic genome editing by combined viral and non-viral delivery of CRISPR system components in vivo H Yin, CQ Song, JR Dorkin, LJ Zhu, Y Li, Q Wu, A Park, J Yang, S Suresh, ... Nature biotechnology 34 (3), 328-333, 2016 | 1006 | 2016 |
Structure-guided chemical modification of guide RNA enables potent non-viral in vivo genome editing H Yin, CQ Song, S Suresh, Q Wu, S Walsh, LH Rhym, E Mintzer, ... Nature biotechnology 35 (12), 1179-1187, 2017 | 533 | 2017 |
A compact, high-accuracy Cas9 with a dinucleotide PAM for in vivo genome editing A Edraki, A Mir, R Ibraheim, I Gainetdinov, Y Yoon, CQ Song, Y Cao, ... Molecular cell 73 (4), 714-726. e4, 2019 | 263 | 2019 |
Partial DNA-guided Cas9 enables genome editing with reduced off-target activity H Yin, CQ Song, S Suresh, SY Kwan, Q Wu, S Walsh, J Ding, RL Bogorad, ... Nature chemical biology 14 (3), 311-316, 2018 | 255 | 2018 |
CRISPR/Cas9-mediated genome editing induces exon skipping by alternative splicing or exon deletion H Mou, JL Smith, L Peng, H Yin, J Moore, XO Zhang, CQ Song, A Sheel, ... Genome biology 18, 1-8, 2017 | 206 | 2017 |
pNovo: De novo Peptide Sequencing and Identification Using HCD Spectra H Chi, RX Sun, B Yang, CQ Song, LH Wang, C Liu, Y Fu, ZF Yuan, ... Journal of proteome research 9 (5), 2713-2724, 2010 | 195 | 2010 |
Adenine base editing in an adult mouse model of tyrosinaemia CQ Song, T Jiang, M Richter, LH Rhym, LW Koblan, MP Zafra, ... Nature biomedical engineering 4 (1), 125-130, 2020 | 190 | 2020 |
Mitoflash frequency in early adulthood predicts lifespan in Caenorhabditis elegans EZ Shen, CQ Song, Y Lin, WH Zhang, PF Su, WY Liu, P Zhang, J Xu, ... Nature 508 (7494), 128-132, 2014 | 143 | 2014 |
Advances in CRISPR/Cas-based gene therapy in human genetic diseases SS Wu, QC Li, CQ Yin, W Xue, CQ Song Theranostics 10 (10), 4374, 2020 | 142 | 2020 |
Genome-wide CRISPR screen identifies regulators of mitogen-activated protein kinase as suppressors of liver tumors in mice CQ Song, Y Li, H Mou, J Moore, A Park, Y Pomyen, S Hough, Z Kennedy, ... Gastroenterology 152 (5), 1161-1173. e1, 2017 | 130 | 2017 |
All-in-one adeno-associated virus delivery and genome editing by Neisseria meningitidis Cas9 in vivo R Ibraheim, CQ Song, A Mir, N Amrani, W Xue, EJ Sontheimer Genome biology 19, 1-11, 2018 | 114 | 2018 |
pNovo+: de novo peptide sequencing using complementary HCD and ETD tandem mass spectra H Chi, H Chen, K He, L Wu, B Yang, RX Sun, J Liu, WF Zeng, CQ Song, ... Journal of proteome research 12 (2), 615-625, 2013 | 108 | 2013 |
In Vivo Genome Editing Partially Restores Alpha1-Antitrypsin in a Murine Model of AAT Deficiency CQ Song, D Wang, T Jiang, K O'Connor, Q Tang, L Cai, X Li, Z Weng, ... Human gene therapy 29 (8), 853-860, 2018 | 85 | 2018 |
pQuant improves quantitation by keeping out interfering signals and evaluating the accuracy of calculated ratios C Liu, CQ Song, ZF Yuan, Y Fu, H Chi, LH Wang, SB Fan, K Zhang, ... Analytical chemistry 86 (11), 5286-5294, 2014 | 78 | 2014 |
Identification and validation of pyroptosis-related gene signature to predict prognosis and reveal immune infiltration in hepatocellular carcinoma XW Fu, CQ Song Frontiers in cell and developmental biology 9, 748039, 2021 | 75 | 2021 |
Targeted metabolomics identifies the cytochrome P450 monooxygenase eicosanoid pathway as a novel therapeutic target of colon tumorigenesis W Wang, J Yang, ML Edin, Y Wang, Y Luo, D Wan, H Yang, CQ Song, ... Cancer research 79 (8), 1822-1830, 2019 | 71 | 2019 |
Nematode sperm maturation triggered by protease involves sperm-secreted serine protease inhibitor (Serpin) Y Zhao, W Sun, P Zhang, H Chi, MJ Zhang, CQ Song, X Ma, Y Shang, ... Proceedings of the National Academy of Sciences 109 (5), 1542-1547, 2012 | 65 | 2012 |
Depletion of TRRAP induces p53‐independent senescence in liver cancer by down‐regulating mitotic genes SY Kwan, A Sheel, CQ Song, XO Zhang, T Jiang, H Dang, Y Cao, ... Hepatology 71 (1), 275-290, 2020 | 62 | 2020 |
Cas9-mediated allelic exchange repairs compound heterozygous recessive mutations in mice D Wang, J Li, CQ Song, K Tran, H Mou, PH Wu, PWL Tai, CA Mendonca, ... Nature biotechnology 36 (9), 839-842, 2018 | 49 | 2018 |
Improved peptide identification for proteomic analysis based on comprehensive characterization of electron transfer dissociation spectra RX Sun, MQ Dong, CQ Song, H Chi, B Yang, LY Xiu, L Tao, ZY Jing, C Liu, ... Journal of Proteome Research 9 (12), 6354-6367, 2010 | 45 | 2010 |