Development of a primary human Small Intestine-on-a-Chip using biopsy-derived organoids M Kasendra, A Tovaglieri, A Sontheimer-Phelps, S Jalili-Firoozinezhad, ... Scientific Reports 8 (1), 2871, 2018 | 705 | 2018 |
Reducing the RNA binding protein TIA1 protects against tau-mediated neurodegeneration in vivo DJ Apicco, PEA Ash, B Maziuk, C LeBlang, M Medalla, A Al Abdullatif, ... Nature neuroscience 21 (1), 72, 2018 | 243 | 2018 |
PD-L1 (B7-H1) Competes with the RNA Exosome to Regulate the DNA Damage Response and Can Be Targeted to Sensitize to Radiation or Chemotherapy X Tu, B Qin, Y Zhang, C Zhang, M Kahila, S Nowsheen, P Yin, J Yuan, ... Molecular cell, 2019 | 214 | 2019 |
p21 produces a bioactive secretome that places stressed cells under immunosurveillance I Sturmlechner, C Zhang, CC Sine, EJ van Deursen, KB Jeganathan, ... Science 374 (6567), eabb3420, 2021 | 199 | 2021 |
Therapeutic target database update 2014: a resource for targeted therapeutics C Qin, C Zhang, F Zhu, F Xu, SY Chen, P Zhang, YH Li, SY Yang, YQ Wei, ... Nucleic acids research 42 (D1), D1118-D1123, 2013 | 157 | 2013 |
Metabolism in Pluripotent Stem Cells and Early Mammalian Development J Zhang, J Zhao, P Dahan, V Lu, C Zhang, H Li, MA Teitell Cell Metabolism 27 (2), 332-338, 2018 | 140 | 2018 |
SVM-Prot 2016: a web-server for machine learning prediction of protein functional families from sequence irrespective of similarity YH Li, JY Xu, L Tao, XF Li, S Li, X Zeng, SY Chen, P Zhang, C Qin, ... PloS one 11 (8), e0155290, 2016 | 138 | 2016 |
RNA binding proteins co-localize with small tau inclusions in tauopathy BF Maziuk, DJ Apicco, AL Cruz, L Jiang, PEA Ash, EL da Rocha, C Zhang, ... Acta neuropathologica communications 6 (1), 71, 2018 | 135 | 2018 |
Interaction of tau with HNRNPA2B1 and N6-methyladenosine RNA mediates the progression of tauopathy L Jiang, W Lin, C Zhang, PEA Ash, M Verma, J Kwan, E van Vliet, Z Yang, ... Molecular Cell 81 (20), 4209-4227. e12, 2021 | 132 | 2021 |
LMO1 Synergizes with MYCN to Promote Neuroblastoma Initiation and Metastasis S Zhu, X Zhang, N Weichert-Leahey, Z Dong, C Zhang, G Lopez, T Tao, ... Cancer cell 32 (3), 310-323. e5, 2017 | 100 | 2017 |
Recent progresses in the exploration of machine learning methods as in-silico ADME prediction tools L Tao, P Zhang, C Qin, SY Chen, C Zhang, Z Chen, F Zhu, SY Yang, ... Advanced drug delivery reviews 86, 83-100, 2015 | 95 | 2015 |
Dysregulation of RNA Splicing in Tauopathies DJ Apicco, C Zhang, B Maziuk, L Jiang, HI Ballance, S Boudeau, C Ung, ... Cell reports 29 (13), 4377-4388. e4, 2019 | 70 | 2019 |
Ccne1 Overexpression Causes Chromosome Instability in Liver Cells and Liver Tumor Development in Mice K Aziz, JF Limzerwala, I Sturmlechner, E Hurley, C Zhang, KB Jeganathan, ... Gastroenterology, 2019 | 65 | 2019 |
Gene‐specific variant classifier (DPYD‐Varifier) to identify deleterious alleles of dihydropyrimidine dehydrogenase S Shrestha, C Zhang, CR Jerde, Q Nie, H Li, SM Offer, RB Diasio Clinical Pharmacology & Therapeutics, 2018 | 64 | 2018 |
TGF-β inhibitors stimulate red blood cell production by enhancing self-renewal of BFU-E erythroid progenitors X Gao, HY Lee, EL Da Rocha, C Zhang, YF Lu, D Li, Y Feng, J Ezike, ... Blood 128 (23), 2637-2641, 2016 | 63 | 2016 |
Machine Learning-assisted network inference approach to identify a new class of genes that coordinate the functionality of cancer networks MG Bari, CY Ung, C Zhang, S Zhu, H Li Scientific Reports 7 (1), 6993, 2017 | 55 | 2017 |
Mitofusin 2 regulates axonal transport of calpastatin to prevent neuromuscular synaptic elimination in skeletal muscles L Wang, J Gao, J Liu, SL Siedlak, S Torres, H Fujioka, ML Huntley, ... Cell metabolism 28 (3), 400-414. e8, 2018 | 53 | 2018 |
Senescent cells suppress innate smooth muscle cell repair functions in atherosclerosis BG Childs, C Zhang, F Shuja, I Sturmlechner, S Trewartha, RF Velasco, ... Nature aging 1 (8), 698-714, 2021 | 48 | 2021 |
Biological Significance of the Suppression of Oxidative Phosphorylation in Induced Pluripotent Stem Cells C Zhang, M Skamagki, Z Liu, A Ananthanarayanan, R Zhao, H Li, K Kim Cell reports 21 (8), 2058-2065, 2017 | 48 | 2017 |
Conserved DNA methylation combined with differential frontal cortex and cerebellar expression distinguishes C9orf72-associated and sporadic ALS, and implicates SERPINA1 in disease MTW Ebbert, CA Ross, LJ Pregent, RJ Lank, C Zhang, RB Katzman, ... Acta neuropathologica 134 (5), 715-728, 2017 | 48 | 2017 |