The M2 splice isoform of pyruvate kinase is important for cancer metabolism and tumour growth HR Christofk, MG Vander Heiden, MH Harris, A Ramanathan, ... Nature 452 (7184), 230-233, 2008 | 3278 | 2008 |
Mitochondrial dysfunction induces senescence with a distinct secretory phenotype CD Wiley, MC Velarde, P Lecot, SU Liu, EA Sarnoski, A Freund, ... Cell metabolism 23 (2), 303-314, 2016 | 1134 | 2016 |
Perturbational profiling of a cell-line model of tumorigenesis by using metabolic measurements A Ramanathan, C Wang, SL Schreiber Proceedings of the National Academy of Sciences 102 (17), 5992-5997, 2005 | 461 | 2005 |
Direct control of mitochondrial function by mTOR A Ramanathan, SL Schreiber Proceedings of the national academy of sciences 106 (52), 22229-22232, 2009 | 412 | 2009 |
Metabolite profiling of blood from individuals undergoing planned myocardial infarction reveals early markers of myocardial injury GD Lewis, RU Wei, E Liu, E Yang, X Shi, M Martinovic, L Farrell, A Asnani, ... The Journal of clinical investigation 118 (10), 3503-3512, 2008 | 330 | 2008 |
Large-scale chemical dissection of mitochondrial function BK Wagner, T Kitami, TJ Gilbert, D Peck, A Ramanathan, SL Schreiber, ... Nature biotechnology 26 (3), 343-351, 2008 | 229 | 2008 |
Peripheral circadian clocks mediate dietary restriction-dependent changes in lifespan and fat metabolism in Drosophila SD Katewa, K Akagi, N Bose, K Rakshit, T Camarella, X Zheng, D Hall, ... Cell metabolism 23 (1), 143-154, 2016 | 194 | 2016 |
A plasma signature of human mitochondrial disease revealed through metabolic profiling of spent media from cultured muscle cells O Shaham, NG Slate, O Goldberger, Q Xu, A Ramanathan, AL Souza, ... Proceedings of the National Academy of Sciences 107 (4), 1571-1575, 2010 | 173 | 2010 |
Oxylipin biosynthesis reinforces cellular senescence and allows detection of senolysis CD Wiley, R Sharma, SS Davis, JA Lopez-Dominguez, KP Mitchell, ... Cell metabolism 33 (6), 1124-1136. e5, 2021 | 133 | 2021 |
Shotgun optical maps of the whole Escherichia coli O157: H7 genome A Lim, ET Dimalanta, KD Potamousis, G Yen, J Apodoca, C Tao, J Lin, ... Genome Research 11 (9), 1584-1593, 2001 | 133 | 2001 |
Vitamin D promotes protein homeostasis and longevity via the stress response pathway genes skn-1, ire-1, and xbp-1 KA Mark, KJ Dumas, D Bhaumik, B Schilling, S Davis, TR Oron, ... Cell reports 17 (5), 1227-1237, 2016 | 113 | 2016 |
Secretion of leukotrienes by senescent lung fibroblasts promotes pulmonary fibrosis CD Wiley, AN Brumwell, SS Davis, JR Jackson, A Valdovinos, C Calhoun, ... JCI insight 4 (24), 2019 | 102 | 2019 |
Carbon metabolism–mediated myogenic differentiation AL Bracha, A Ramanathan, S Huang, DE Ingber, SL Schreiber Nature chemical biology 6 (3), 202-204, 2010 | 95 | 2010 |
The aging metabolome—biomarkers to hub metabolites R Sharma, A Ramanathan Proteomics 20 (5-6), 1800407, 2020 | 92 | 2020 |
A Drosophila model identifies a critical role for zinc in mineralization for kidney stone disease T Chi, MS Kim, S Lang, N Bose, A Kahn, L Flechner, SD Blaschko, T Zee, ... PloS one 10 (5), e0124150, 2015 | 91 | 2015 |
A Caenorhabditis elegans model elucidates a conserved role for TRPA1-Nrf signaling in reactive α-dicarbonyl detoxification J Chaudhuri, N Bose, J Gong, D Hall, A Rifkind, D Bhaumik, TH Peiris, ... Current Biology 26 (22), 3014-3025, 2016 | 90 | 2016 |
α-Lipoic acid treatment prevents cystine urolithiasis in a mouse model of cystinuria T Zee, N Bose, J Zee, JN Beck, S Yang, J Parihar, M Yang, S Damodar, ... Nature medicine 23 (3), 288-290, 2017 | 69 | 2017 |
An integrative approach for the optical sequencing of single DNA molecules A Ramanathan, EJ Huff, CC Lamers, KD Potamousis, DK Forrest, ... Analytical Biochemistry 330 (2), 227-241, 2004 | 40 | 2004 |
Metformin inhibits Branched Chain Amino Acid (BCAA) derived ketoacidosis and promotes metabolic homeostasis in MSUD DS Sonnet, MN O’Leary, M A. Gutierrez, SM Nguyen, S Mateen, Y Hsu, ... Scientific Reports 6 (1), 28775, 2016 | 37 | 2016 |
A novel AhR ligand, 2AI, protects the retina from environmental stress MA Gutierrez, SS Davis, A Rosko, SM Nguyen, KP Mitchell, S Mateen, ... Scientific reports 6 (1), 29025, 2016 | 36 | 2016 |