Anti-colon cancer activity of Murraya koenigii leaves is due to constituent murrayazoline and O-methylmurrayamine A induced mTOR/AKT downregulation and mitochondrial apoptosis A Arun, OPS Patel, D Saini, PP Yadav, R Konwar Biomedicine & Pharmacotherapy 93, 510-521, 2017 | 50 | 2017 |
piRNAs as modulators of disease pathogenesis KJ Rayford, A Cooley, JT Rumph, A Arun, G Rachakonda, F Villalta, ... International Journal of Molecular Sciences 22 (5), 2373, 2021 | 45 | 2021 |
Synthesis of targeted dibenzo [b, f] thiepines and dibenzo [b, f] oxepines as potential lead molecules with promising anti-breast cancer activity MI Ansari, MK Hussain, A Arun, B Chakravarti, R Konwar, K Hajela European Journal of Medicinal Chemistry 99, 113-124, 2015 | 42 | 2015 |
Pyranocarbazole derivatives as potent anti-cancer agents triggering tubulin polymerization stabilization induced activation of caspase-dependent apoptosis and downregulation of … OPS Patel, A Arun, PK Singh, D Saini, SS Karade, MK Chourasia, ... European journal of medicinal chemistry 167, 226-244, 2019 | 32 | 2019 |
Design, synthesis and in vitro evaluation of coumarin–imidazo [1, 2-a] pyridine derivatives against cancer induced osteoporosis KV Sashidhara, LR Singh, D Choudhary, A Arun, S Gupta, S Adhikary, ... RSC Advances 6 (83), 80037-80048, 2016 | 31 | 2016 |
Identification of gallic acid based glycoconjugates as a novel tubulin polymerization inhibitors K Upadhyaya, Hamidullah, K Singh, A Arun, M Shukla, N Srivastava, ... Organic & biomolecular chemistry 14 (4), 1338-1358, 2016 | 30 | 2016 |
Bivalent approach for homodimeric estradiol based ligand: synthesis and evaluation for targeted theranosis of ER (+) breast carcinomas K Chauhan, A Arun, S Singh, M Manohar, K Chuttani, R Konwar, ... Bioconjugate Chemistry 27 (4), 961-972, 2016 | 25 | 2016 |
New piperidine derivative DTPEP acts as dual‐acting anti‐breast cancer agent by targeting ER α and downregulating PI 3K/Akt‐PKC α leading to caspase‐dependent apoptosis A Arun, MI Ansari, P Popli, S Jaiswal, AK Mishra, A Dwivedi, K Hajela, ... Cell proliferation 51 (6), e12501, 2018 | 20 | 2018 |
Discovery of 3, 4, 6‐Triaryl‐2‐pyridones as potential anticancer agents that promote ROS‐independent mitochondrial‐mediated apoptosis in human breast carcinoma cells MI Ansari, A Arun, MK Hussain, R Konwar, K Hajela ChemistrySelect 1 (14), 4255-4264, 2016 | 14 | 2016 |
Trypanosoma cruzi Modulates PIWI-Interacting RNA Expression in Primary Human Cardiac Myocytes during the Early Phase of Infection KJ Rayford, A Cooley, A Arun, G Rachakonda, Y Kleschenko, F Villalta, ... International Journal of Molecular Sciences 21 (24), 9439, 2020 | 11 | 2020 |
Thrombospondin-1 Plays an Essential Role in Yes-Associated Protein Nuclear Translocation during the Early Phase of Trypanosoma cruzi Infection in Heart … A Arun, KJ Rayford, A Cooley, G Rachakonda, F Villalta, S Pratap, ... International Journal of Molecular Sciences 21 (14), 4912, 2020 | 11 | 2020 |
Trypanosoma cruzi dysregulates expression profile of piRNAs in primary human cardiac fibroblasts during early infection phase KJ Rayford, A Cooley, AW Strode, I Osi, A Arun, MF Lima, S Misra, ... Frontiers in Cellular and Infection Microbiology 13, 1083379, 2023 | 7 | 2023 |
Thrombospondin-1 expression and modulation of Wnt and hippo signaling pathways during the early phase of Trypanosoma cruzi infection of heart endothelial cells A Arun, KJ Rayford, A Cooley, T Rana, G Rachakonda, F Villalta, S Pratap, ... PLoS Neglected Tropical Diseases 16 (1), e0010074, 2022 | 5 | 2022 |
Trypanosoma cruzi Dysregulates piRNAs Computationally Predicted to Target IL-6 Signaling Molecules During Early Infection of Primary Human Cardiac Fibroblasts A Cooley, KJ Rayford, A Arun, F Villalta, MF Lima, S Pratap, PN Nde Immune Network 22 (6), 2022 | 4 | 2022 |
Xanthine Analogs Suppress Trypanosoma cruzi Infection In Vitro Using PDEs as Targets AR Banga, KR Sekhar, KJ Rayford, A Arun, P Odiase, AP Garg, MF Lima, ... Microbiology Research 13 (4), 721-739, 2022 | 4 | 2022 |
Trypanosoma cruzi dysregulates expression of piRNA that can regulate IL‐6 signaling in human cardiac fibroblasts during the early phase of infection KJ Rayford, A Cooley, A Arun, G Rachakonda, F Villalta, MF Lima, ... The FASEB Journal 36, 2022 | 2 | 2022 |
Trypanasoma cruzi dystegulates piRNA computationally predicted to target proinflammatory molecules in Primary Human Cardiac Myocytes during Early Infection Phase A Cooley, K Rayford, A Arun, P Nde, S Pratap Journal of Biological Chemistry 299 (3), 104257, 2023 | | 2023 |
Trypanosoma cruzi dysregulates piRNAs targeting IL-6 signaling pathway in primary human cardiac fibroblasts during acute infection K Rayford, A Cooley, A Strode, I Osi, A Arun, S Pratap, P Nde Journal of Biological Chemistry 299 (3), 103160, 2023 | | 2023 |
Analysis Pipeline of PIWI‐Interacting RNA (piRNA) in an Inflammatory Parasitic Infectious Disease A Cooley, K Rayford, A Arun, G Rachakonda, Y Kleschenko, F Villalta, ... The FASEB Journal 35, 2021 | | 2021 |
Thrombospondin‐1 Plays an Essential Role in Hippo Signaling During the Early Phase of Trypanosoma cruzi Infection in Heart Endothelial Cells A Arun, K Rayford, A Cooley, G Rachakonda, F Villalta, S Pratap, M Lima, ... The FASEB Journal 35, 2021 | | 2021 |