| Cyclophilin D deficiency attenuates mitochondrial and neuronal perturbation and ameliorates learning and memory in Alzheimer's disease H Du, L Guo, F Fang, D Chen, A A Sosunov, G M McKhann, Y Yan, ... Nature medicine 14 (10), 1097-1105, 2008 | 1056 | 2008 |
| Amyloid β protein and Alzheimer’s disease: When computer simulations complement experimental studies J Nasica-Labouze, PH Nguyen, F Sterpone, O Berthoumieu, NV Buchete, ... Chemical reviews 115 (9), 3518-3563, 2015 | 642 | 2015 |
| The Alzheimer’s peptides Aβ40 and 42 adopt distinct conformations in water: a combined MD/NMR study NG Sgourakis, Y Yan, SA McCallum, C Wang, AE Garcia Journal of molecular biology 368 (5), 1448-1457, 2007 | 552 | 2007 |
| Lysine-specific molecular tweezers are broad-spectrum inhibitors of assembly and toxicity of amyloid proteins S Sinha, DHJ Lopes, Z Du, ES Pang, A Shanmugam, A Lomakin, ... Journal of the American Chemical Society 133 (42), 16958-16969, 2011 | 348 | 2011 |
| Aβ42 is more rigid than Aβ40 at the C terminus: implications for Aβ aggregation and toxicity Y Yan, C Wang Journal of molecular biology 364 (5), 853-862, 2006 | 343 | 2006 |
| Rational stabilization of enzymes by computational redesign of surface charge–charge interactions AV Gribenko, MM Patel, J Liu, SA McCallum, C Wang, GI Makhatadze Proceedings of the National Academy of Sciences 106 (8), 2601-2606, 2009 | 289 | 2009 |
| Aβ monomers transiently sample oligomer and fibril-like configurations: Ensemble characterization using a combined MD/NMR approach DJ Rosenman, CR Connors, W Chen, C Wang, AE García Journal of molecular biology 425 (18), 3338-3359, 2013 | 248 | 2013 |
| Atomic-level characterization of the ensemble of the Aβ (1–42) monomer in water using unbiased molecular dynamics simulations and spectral algorithms NG Sgourakis, M Merced-Serrano, C Boutsidis, P Drineas, Z Du, C Wang, ... Journal of molecular biology 405 (2), 570-583, 2011 | 246 | 2011 |
| NMR R 1ρ rotating-frame relaxation with weak radio frequency fields F Massi, E Johnson, C Wang, M Rance, AG Palmer Journal of the American Chemical Society 126 (7), 2247-2256, 2004 | 189 | 2004 |
| Disulfide bond isomerization in basic pancreatic trypsin inhibitor: multisite chemical exchange quantified by CPMG relaxation dispersion and chemical shift modeling MJ Grey, C Wang, AG Palmer Journal of the American Chemical Society 125 (47), 14324-14335, 2003 | 175 | 2003 |
| γ-Secretase substrate concentration modulates the Aβ42/Aβ40 ratio: Implications for Alzheimer disease YI Yin, B Bassit, L Zhu, X Yang, C Wang, YM Li Journal of Biological Chemistry 282 (32), 23639-23644, 2007 | 166 | 2007 |
| Targeting amyloidogenic processing of APP in Alzheimer’s disease J Zhao, X Liu, W Xia, Y Zhang, C Wang Frontiers in molecular neuroscience 13, 137, 2020 | 154 | 2020 |
| Comparison of Three Amyloid Assembly Inhibitors: The Sugar scyllo-Inositol, the Polyphenol Epigallocatechin Gallate, and the Molecular Tweezer CLR01 S Sinha, Z Du, P Maiti, FG Klärner, T Schrader, C Wang, G Bitan ACS chemical neuroscience 3 (6), 451-458, 2012 | 150 | 2012 |
| Identification of the peptide sequences within the EIIIA (EDA) segment of fibronectin that mediate integrin α9β1-dependent cellular activities AV Shinde, C Bystroff, C Wang, MG Vogelezang, PA Vincent, RO Hynes, ... Journal of Biological Chemistry 283 (5), 2858-2870, 2008 | 136 | 2008 |
| Solution structure of ThiS and implications for the evolutionary roots of ubiquitin C Wang, J Xi, TP Begley, LK Nicholson Nature structural biology 8 (1), 47-51, 2001 | 131 | 2001 |
| EGCG binds intrinsically disordered N-terminal domain of p53 and disrupts p53-MDM2 interaction J Zhao, A Blayney, X Liu, L Gandy, W Jin, L Yan, JH Ha, AJ Canning, ... Nature communications 12 (1), 986, 2021 | 130 | 2021 |
| Aβ40 protects non-toxic Aβ42 monomer from aggregation Y Yan, C Wang Journal of molecular biology 369 (4), 909-916, 2007 | 128 | 2007 |
| Solution NMR spin relaxation methods for characterizing chemical exchange in high-molecular-weight systems AG Palmer III, MJ Grey, C Wang Methods in enzymology 394, 430-465, 2005 | 126 | 2005 |
| Carbon dots: A future Blood–Brain Barrier penetrating nanomedicine and drug nanocarrier W Zhang, G Sigdel, KJ Mintz, ES Seven, Y Zhou, C Wang, RM Leblanc International journal of nanomedicine, 5003-5016, 2021 | 115 | 2021 |
| The role of backbone motions in ligand binding to the c-Src SH3 domain C Wang, NH Pawley, LK Nicholson Journal of molecular biology 313 (4), 873-887, 2001 | 114 | 2001 |
Robert LinhardtEmeritus Professor, Rensselaer Polytechnic Institute確認したメール アドレス: rpi.edu
