Subgroup-specific structural variation across 1,000 medulloblastoma genomes PA Northcott, DJH Shih, J Peacock, L Garzia, A Sorana Morrissy, ... Nature 488 (7409), 49-56, 2012 | 1014 | 2012 |
YAP1 is amplified and up-regulated in hedgehog-associated medulloblastomas and mediates Sonic hedgehog-driven neural precursor proliferation A Fernandez-L, PA Northcott, J Dalton, C Fraga, D Ellison, S Angers, ... Genes & development 23 (23), 2729-2741, 2009 | 449 | 2009 |
The miR-17/92 polycistron is up-regulated in Sonic Hedgehog–driven medulloblastomas and induced by N-myc in Sonic Hedgehog–treated cerebellar neural precursors PA Northcott, A Fernandez-L, JP Hagan, DW Ellison, W Grajkowska, ... Cancer research 69 (8), 3249-3255, 2009 | 340 | 2009 |
Characterization of a new subpopulation of mouse CD8alpha+ B220+ dendritic cells endowed with type 1 interferon production capacity and tolerogenic potential P Martín, GM Del Hoyo, F Anjuère, CF Arias, HH Vargas, A Fernández-L, ... Blood 100 (2), 383-390, 2002 | 312 | 2002 |
Hereditary hemorrhagic telangiectasia, a vascular dysplasia affecting the TGF-β signaling pathway A Fernández-L, F Sanz-Rodriguez, FJ Blanco, C Bernabéu, LM Botella Clinical medicine & research 4 (1), 66-78, 2006 | 219 | 2006 |
Oncogenic YAP promotes radioresistance and genomic instability in medulloblastoma through IGF2-mediated Akt activation A Fernandez-L, M Squatrito, P Northcott, A Awan, EC Holland, MD Taylor, ... Oncogene 31 (15), 1923-1937, 2012 | 174 | 2012 |
Blood outgrowth endothelial cells from Hereditary Haemorrhagic Telangiectasia patients reveal abnormalities compatible with vascular lesions A Fernandez-L, F Sanz-Rodriguez, R Zarrabeitia, A Pérez-Molino, ... Cardiovascular research 68 (2), 235-248, 2005 | 126 | 2005 |
Therapeutic action of tranexamic acid in hereditary haemorrhagic telangiectasia (HHT): regulation of ALK-1/endoglin pathway in endothelial cells A Fernandez-L, EM Garrido-Martin, F Sanz-Rodriguez, JR Ramirez, ... Thrombosis and haemostasis 97 (02), 254-262, 2007 | 84 | 2007 |
Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia and expression analysis of Endoglin and ALK1 A Fernandez‐L, F Sanz‐Rodriguez, R Zarrabeitia, A Perez‐Molino, ... Human Mutation 27 (3), 295-295, 2006 | 74 | 2006 |
Gene expression fingerprinting for human hereditary hemorrhagic telangiectasia A Fernandez-Lopez, EM Garrido-Martin, F Sanz-Rodriguez, M Pericacho, ... Human molecular genetics 16 (13), 1515-1533, 2007 | 71 | 2007 |
TGF-β regulates the expression of transcription factor KLF6 and its splice variants and promotes co-operative transactivation of common target genes through a Smad3–Sp1–KLF6 … LM Botella, F Sanz-Rodriguez, Y Komi, A Fernandez-l, E Varela, ... Biochemical Journal 419 (2), 485-495, 2009 | 61 | 2009 |
Mutation analysis in Spanish patients with hereditary hemorrhagic telangiectasia: deficient endoglin up-regulation in activated monocytes F Sanz-Rodriguez, A Fernandez-L, R Zarrabeitia, A Perez-Molino, ... Clinical chemistry 50 (11), 2003-2011, 2004 | 59 | 2004 |
Insulin receptor substrate 1 is an effector of sonic hedgehog mitogenic signaling in cerebellar neural precursors SR Parathath, LA Mainwaring, A Fernandez-L, DO Campbell, AM Kenney Oxford University Press for The Company of Biologists Limited 135 (19), 3291 …, 2008 | 57 | 2008 |
Mutation study of Spanish patients with hereditary hemorrhagic telangiectasia A Fontalba, A Fernandez-L, E García-Alegria, V Albiñana, ... BMC Medical Genetics 9, 1-8, 2008 | 47 | 2008 |
Characterization of the human Activin-A receptor type II-like kinase 1 (ACVRL1) promoter and its regulation by Sp1 EM Garrido-Martin, FJ Blanco, A Fernandez-L, C Langa, CP Vary, UE Lee, ... BMC molecular biology 11, 1-22, 2010 | 46 | 2010 |
p27Kip1, a double-edged sword in Shh-mediated medulloblastoma: Tumor accelerator and suppressor B Bhatia, A Malik, A Fernandez-L, AM Kenney Cell Cycle 9 (21), 4307-4314, 2010 | 36 | 2010 |
The TGF-β co-receptor endoglin modulates the expression and transforming potential of H-Ras JF Santibanez, E Pérez-Gómez, A Fernandez-L, EM Garrido-Martin, ... Carcinogenesis 31 (12), 2145-2154, 2010 | 35 | 2010 |
β-Arrestin-1 links mitogenic sonic hedgehog signaling to the cell cycle exit machinery in neural precursors SR Parathath, LA Mainwaring, A Fernandez-L, CG Guldal, Z Nahlé, ... Cell Cycle 9 (19), 4013-4024, 2010 | 32 | 2010 |
Normal and oncogenic roles for microRNAs in the developing brain A Fernandez-L, PA Northcott, MD Taylor, AM Kenney Cell Cycle 8 (24), 4049-4054, 2009 | 32 | 2009 |
The Hippo in the room: a new look at a key pathway in cell growth and transformation A Fernandez-L, AM Kenney Cell cycle 9 (12), 2292-2299, 2010 | 30 | 2010 |