| Characterization of the p300 Taz2–p53 TAD2 complex and comparison with the p300 Taz2–p53 TAD1 complex LM Miller Jenkins, H Feng, SR Durell, HD Tagad, SJ Mazur, JE Tropea, ... Biochemistry 54 (11), 2001-2010, 2015 | 64 | 2015 |
| Design of pentapeptidic BACE1 inhibitors with carboxylic acid bioisosteres at P1′ and P4 positions HD Tagad, Y Hamada, JT Nguyen, T Hamada, H Abdel-Rahman, ... Bioorganic & medicinal chemistry 18 (9), 3175-3186, 2010 | 37 | 2010 |
| Binding of a third metal ion by the human phosphatases PP2Cα and Wip1 is required for phosphatase activity K Tanoue, LM Miller Jenkins, SR Durell, S Debnath, H Sakai, HD Tagad, ... Biochemistry 52 (34), 5830-5843, 2013 | 36 | 2013 |
| Intensity and duration of TCR signaling is limited by p38 phosphorylation of ZAP-70T293 and destabilization of the signalosome ML Giardino Torchia, D Dutta, PR Mittelstadt, J Guha, MM Gaida, K Fish, ... Proceedings of the National Academy of Sciences 115 (9), 2174-2179, 2018 | 34 | 2018 |
| Tripeptidic BACE1 inhibitors devised by in-silico conformational structure-based design Y Hamada, HD Tagad, Y Nishimura, S Ishiura, Y Kiso Bioorganic & medicinal chemistry letters 22 (2), 1130-1135, 2012 | 27 | 2012 |
| Structure-guided design and synthesis of P1′ position 1-phenylcycloalkylamine-derived pentapeptidic BACE1 inhibitors HD Tagad, Y Hamada, JT Nguyen, K Hidaka, T Hamada, Y Sohma, ... Bioorganic & medicinal chemistry 19 (17), 5238-5246, 2011 | 26 | 2011 |
| Cooperative assembly of a four-molecule signaling complex formed upon T cell antigen receptor activation A Manna, H Zhao, J Wada, L Balagopalan, HD Tagad, E Appella, ... Proceedings of the National Academy of Sciences 115 (51), E11914-E11923, 2018 | 25 | 2018 |
| A trapped human PPM1A–phosphopeptide complex reveals structural features critical for regulation of PPM protein phosphatase activity S Debnath, D Kosek, HD Tagad, SR Durell, DH Appella, R Acevedo, ... Journal of Biological Chemistry 293 (21), 7993-8008, 2018 | 24 | 2018 |
| Unique properties of TCR-activated p38 are necessary for NFAT-dependent T-cell activation MS Alam, MM Gaida, S Debnath, HD Tagad, LM Miller Jenkins, E Appella, ... PLoS biology 16 (1), e2004111, 2018 | 23 | 2018 |
| Chemical features important for activity in a class of inhibitors targeting the Wip1 flap subdomain HD Tagad, S Debnath, V Clausse, M Saha, SJ Mazur, E Appella, ... ChemMedChem 13 (9), 894-901, 2018 | 11 | 2018 |
| Discovery of novel small-molecule scaffolds for the inhibition and activation of WIP1 Phosphatase from a rapidfire mass spectrometry high-throughput screen V Clausse, Y Fang, D Tao, HD Tagad, H Sun, Y Wang, S Karavadhi, ... ACS Pharmacology & Translational Science 5 (10), 993-1006, 2022 | 8 | 2022 |
| Physiologically relevant orthogonal assays for the discovery of small-molecule modulators of WIP1 phosphatase in high-throughput screens V Clausse, D Tao, S Debnath, Y Fang, HD Tagad, Y Wang, H Sun, ... Journal of Biological Chemistry 294 (46), 17654-17668, 2019 | 8 | 2019 |
| Monitoring Protein Complexation with Polyphosphazene Polyelectrolyte Using Automated Dynamic Light Scattering Titration and Asymmetric Flow Field Flow Fractionation and Protein … M Lueckheide, A Marin, HD Tagad, ND Posey, VM Prabhu, AK Andrianov ACS Polymers Au 3 (5), 354-364, 2023 | 7 | 2023 |
| Tetrapeptides, as small‐sized peptidic inhibitors; synthesis and their inhibitory activity against BACE1 T Kakizawa, K Hidaka, D Hamada, R Yamaguchi, T Uemura, H Kitamura, ... Journal of Peptide Science: An Official Publication of the European Peptide …, 2010 | 6 | 2010 |
| Fluorine-Functionalized Polyphosphazene Immunoadjuvant: Synthesis, Solution Behavior and In Vivo Potency HD Tagad, A Marin, R Wang, AS Yunus, TR Fuerst, AK Andrianov Molecules 28 (10), 4218, 2023 | 2 | 2023 |
| 4-Methylumbelliferone-Functionalized Polyphosphazene and Its Assembly into Biocompatible Fluorinated Nanocoatings with Selective Antiproliferative Activity HD Tagad, J Brito, A Marin, C Buckley, H Wang, J Sun, SA Sukhishvili, ... Biomacromolecules 24 (5), 2278-2290, 2023 | 1 | 2023 |
| Covalent Modification of p53 by (E)-1-(4-Methylpiperazin-1-yl)-3-(5-nitrofuran-2-yl)prop-2-en-1-one K Brown, M Robello, AJ Perciaccante, JC Dinan, TK Maity, GC Lyons, ... ACS Pharmacology & Translational Science 7 (11), 3559-3572, 2024 | | 2024 |
| Hydrolytically Degradable Zwitterionic Polyphosphazene Containing HEPES Moieties as Side Groups HD Tagad, A Marin, R Hlushko, AK Andrianov Biomacromolecules 25 (10), 6791-6800, 2024 | | 2024 |
| Alkyl-substituted N-methylaryl-N′-aryl-4-aminobenzamides: A new series of small molecule inhibitors for Wip1 phosphatase M Robello, H Zheng, M Saha, KMG Rosenker, S Debnath, JP Kumar, ... European journal of medicinal chemistry 243, 114763, 2022 | | 2022 |
| Design, synthesis and SAR of potent penta-, tetra-, and tri-peptidomimetic inhibitors targeting human β-secretase (BACE1) HD Tagad 京都薬科大学, 2011 | | 2011 |
Hamdy Abdel-RahmanFaculty of Pharmacy, Assiut University and Badr University in Assiut (BUA)確認したメール アドレス: bua.edu.eg