| Photoactivation of channelrhodopsin OP Ernst, PAS Murcia, P Daldrop, SP Tsunoda, S Kateriya, P Hegemann Journal of Biological Chemistry 283 (3), 1637-1643, 2008 | 191 | 2008 |
| Translation elongation factor eEF1A2 is a novel anticancer target for the marine natural product plitidepsin A Losada, MJ Muñoz-Alonso, C García, PA Sánchez-Murcia, ... Scientific reports 6 (1), 35100, 2016 | 87 | 2016 |
| Enzymatic Synthesis of Therapeutic Nucleosides using a Highly Versatile Purine Nucleoside 2’‐DeoxyribosylTransferase from Trypanosoma brucei E Pérez, PA Sánchez‐Murcia, J Jordaan, MD Blanco, JM Mancheño, ... ChemCatChem 10 (19), 4406-4416, 2018 | 43 | 2018 |
| A series of enthalpically optimized docetaxel analogues exhibiting enhanced antitumor activity and water solubility YT Ma, Y Yang, P Cai, DY Sun, PA Sánchez-Murcia, XY Zhang, WQ Jia, ... Journal of Natural Products 81 (3), 524-533, 2018 | 42 | 2018 |
| First example of peptides targeting the dimer interface of Leishmania infantum trypanothione reductase with potent in vitro antileishmanial activity M Ruiz-Santaquiteria, PA Sánchez-Murcia, MA Toro, H de Lucio, ... European Journal of Medicinal Chemistry 135, 49-59, 2017 | 40 | 2017 |
| Pyrrolopyrimidine vs Imidazole-Phenyl-Thiazole Scaffolds in Nonpeptidic Dimerization Inhibitors of Leishmania infantum Trypanothione Reductase A Revuelto, M Ruiz-Santaquiteria, H de Lucio, A Gamo, AA Carriles, ... ACS Infectious Diseases 5 (6), 873-891, 2019 | 35 | 2019 |
| Probing the dimerization interface of Leishmania infantum trypanothione reductase with site-directed mutagenesis and short peptides. MA Toro, PA Sanchez-Murcia, D Moreno, M Ruiz-Santaquiteria, JF Alzate, ... Chembiochem: a European Journal of Chemical Biology 14 (10), 1212-1217, 2013 | 35 | 2013 |
| Excimer intermediates en route to long-lived charge-transfer states in single-stranded adenine DNA as revealed by nonadiabatic dynamics LM Ibele, PA Sanchez-Murcia, S Mai, JJ Nogueira, L González The Journal of Physical Chemistry Letters 11 (18), 7483-7488, 2020 | 34 | 2020 |
| 2′-Deoxyribosyltransferase from Leishmania mexicana, an efficient biocatalyst for one-pot, one-step synthesis of nucleosides from poorly soluble purine bases N Crespo, PA Sánchez-Murcia, F Gago, J Cejudo-Sanches, MA Galmes, ... Applied microbiology and biotechnology 101, 7187-7200, 2017 | 34 | 2017 |
| Modular architecture and unique teichoic acid recognition features of choline-binding protein L (CbpL) contributing to pneumococcal pathogenesis J Gutiérrez-Fernández, M Saleh, M Alcorlo, A Gómez-Mejía, ... Scientific Reports 6 (1), 38094, 2016 | 34 | 2016 |
| Formal asymmetric enone aminohydroxylation: organocatalytic one-pot synthesis of 4, 5-disubstituted oxazolidinones DC Cruz, PA Sánchez-Murcia, KA Jørgensen Chemical Communications 48 (49), 6112-6114, 2012 | 32 | 2012 |
| Structural rationale for the cross-resistance of tumor cells bearing the A399V variant of elongation factor eEF1A1 to the structurally unrelated didemnin B, ternatin … PA Sánchez-Murcia, Á Cortés-Cabrera, F Gago Journal of Computer-Aided Molecular Design 31 (10), 915-928, 2017 | 31 | 2017 |
| Molecular recognition of epothilones by microtubules and tubulin dimers revealed by biochemical and NMR approaches A Canales, L Nieto, J Rodríguez-Salarichs, PA Sanchez-Murcia, ... ACS chemical biology 9 (4), 1033-1043, 2014 | 31 | 2014 |
| Characterization of an atypical, thermostable, organic solvent- and acid-tolerant 2′-deoxyribosyltransferase from Chroococcidiopsis thermalis J Del Arco, PA Sánchez-Murcia, JM Mancheño, F Gago, ... Applied Microbiology and Biotechnology 102, 6947-6957, 2018 | 24 | 2018 |
| Molecular interactions and implications of aldose reductase inhibition by PGA1 and clinically used prostaglandins B Díez-Dacal, FJ Sánchez-Gómez, PA Sánchez-Murcia, I Milackova, ... Molecular Pharmacology 89 (1), 42-52, 2016 | 24 | 2016 |
| A Supramolecular Stabilizer of the 14‐3‐3ζ/ERα Protein‐Protein Interaction with a Synergistic Mode of Action A Gigante, E Sijbesma, PA Sánchez‐Murcia, X Hu, D Bier, S Bäcker, ... Angewandte Chemie International Edition 59 (13), 5284-5287, 2020 | 23 | 2020 |
| Structural determinants of the dictyostatin chemotype for tubulin binding affinity and antitumor activity against taxane-and epothilone-resistant cancer cells C Trigili, I Barasoain, PA Sánchez-Murcia, K Bargsten, ... ACS omega 1 (6), 1192-1204, 2016 | 23 | 2016 |
| Reaction mechanism of nucleoside 2′-deoxyribosyltransferases: free-energy landscape supports an oxocarbenium ion as the reaction intermediate J Del Arco, A Perona, L González, J Fernández-Lucas, F Gago, ... Organic & Biomolecular Chemistry 17 (34), 7891-7899, 2019 | 22 | 2019 |
| Trypanothione reductase inhibition and anti-leishmanial activity of all-hydrocarbon stapled α-helical peptides with improved proteolytic stability M Ruiz-Santaquiteria, S de Castro, MA Toro, H de Lucio, KJ Gutiérrez, ... European Journal of Medicinal Chemistry 149, 238-247, 2018 | 22 | 2018 |
| Efficient Dimerization Disruption of Leishmania infantum Trypanothione Reductase by Triazole-phenyl-thiazoles A Revuelto, H de Lucio, JC García-Soriano, PA Sánchez-Murcia, F Gago, ... Journal of Medicinal Chemistry 64 (9), 6137-6160, 2021 | 19 | 2021 |
