Structural and mechanistic insights into the bacterial amyloid secretion channel CsgG P Goyal, PV Krasteva, N Van Gerven, F Gubellini, I Van den Broeck, ... Nature 516 (7530), 250-253, 2014 | 351 | 2014 |
Substrate-bound outward-open structure of a Na+-coupled sialic acid symporter reveals a new Na+ site WY Wahlgren, E Dunevall, RA North, A Paz, M Scalise, P Bisignano, ... Nature Communications 9 (1), 1753, 2018 | 88 | 2018 |
Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors S Sainas, AC Pippione, E Lupino, M Giorgis, P Circosta, V Gaidano, ... Journal of medicinal chemistry 61 (14), 6034-6055, 2018 | 70 | 2018 |
Design, synthesis, biological evaluation and X-ray structural studies of potent human dihydroorotate dehydrogenase inhibitors based on hydroxylated azole scaffolds S Sainas, AC Pippione, M Giorgis, E Lupino, P Goyal, C Ramondetti, ... European Journal of Medicinal Chemistry 129, 287-302, 2017 | 66 | 2017 |
Potent and selective aldo-keto reductase 1C3 (AKR1C3) inhibitors based on the benzoisoxazole moiety: application of a bioisosteric scaffold hopping approach to flufenamic acid AC Pippione, IM Carnovale, D Bonanni, M Sini, P Goyal, E Marini, K Pors, ... European Journal of Medicinal Chemistry 150, 930-945, 2018 | 58 | 2018 |
Secretion and functional display of fusion proteins through the curli biogenesis pathway N Van Gerven, P Goyal, G Vandenbussche, M De Kerpel, W Jonckheere, ... Molecular microbiology 91 (5), 1022-1035, 2014 | 58 | 2014 |
Bioisosteres of indomethacin as inhibitors of aldo-keto reductase 1C3 ML Lolli, IM Carnovale, AC Pippione, WY Wahlgren, D Bonanni, E Marini, ... ACS medicinal chemistry letters 10 (4), 437-443, 2019 | 43 | 2019 |
“Just a spoonful of sugar...”: import of sialic acid across bacterial cell membranes RA North, CR Horne, JS Davies, DM Remus, AC Muscroft-Taylor, P Goyal, ... Biophysical Reviews 10, 219-227, 2018 | 40 | 2018 |
Hydroxyazole scaffold-based Plasmodium falciparum dihydroorotate dehydrogenase inhibitors: Synthesis, biological evaluation and X-ray structural studies AC Pippione, S Sainas, P Goyal, I Fritzson, GC Cassiano, A Giraudo, ... European journal of medicinal chemistry 163, 266-280, 2019 | 37 | 2019 |
Multiple enzymatic activities of ParB/Srx superfamily mediate sexual conflict among conjugative plasmids P Maindola, R Raina, P Goyal, K Atmakuri, A Ojha, S Gupta, PJ Christie, ... Nature communications 5 (1), 5322, 2014 | 30 | 2014 |
Crystallization and preliminary X-ray crystallographic analysis of the curli transporter CsgG P Goyal, N Van Gerven, W Jonckheere, H Remaut Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 17 | 2013 |
Mechanistic insights into global suppressors of protein folding defects G Chattopadhyay, J Bhowmick, K Manjunath, S Ahmed, P Goyal, ... PLoS Genetics 18 (8), e1010334, 2022 | 13 | 2022 |
Crystal structure of N-acetylmannosamine kinase from Fusobacterium nucleatum R Caing-Carlsson, P Goyal, A Sharma, S Ghosh, TG Setty, RA North, ... Acta Crystallographica Section F: Structural Biology Communications 73 (6 …, 2017 | 10 | 2017 |
The mannose-specific lectin domains of Flo1p from Saccharomyces cerevisiae and Lg-Flo1p from S. pastorianus: crystallization and preliminary X-ray diffraction analysis of the … FS Ielasi, P Goyal, M Sleutel, A Wohlkonig, RG Willaert Acta Crystallographica Section F: Structural Biology and Crystallization …, 2013 | 8 | 2013 |
Insights in peptide diffusion channels from the bacterial amyloid secretor CsgG I Van den Broeck, P Goyal, H Remaut Channels 9 (2), 65-67, 2015 | 7 | 2015 |
Molecular determinants of Neu5Ac binding to a tripartite ATP independent periplasmic (TRAP) transporter P Goyal, KV Dhanabalan, M Scalise, R Friemann, C Indiveri, RCJ Dobson, ... eLife 13, RP98158, 2025 | 2 | 2025 |
1C3 (AKR1C3) ML Lolli, IM Carnovale, AC Pippione, WY Wahlgren, D Bonanni, E Marini, ... | | 2024 |
Targeting Multiple proteins that Scavenge, transport, and metabolize Neu5Ac in Gram-ve bacteria. P Goyal, KV Dhanabalan, VK Kutti, R Subramanian Foundations of Crystallography 79, C11, 2023 | | 2023 |
Correction to Targeting Myeloid Differentiation Using Potent 2-Hydroxypyrazolo[1,5-a]pyridine Scaffold-Based Human Dihydroorotate Dehydrogenase Inhibitors S Sainas, AC Pippione, E Lupino, M Giorgis, P Circosta, V Gaidano, ... Journal of Medicinal Chemistry 62 (3), 1696-1696, 2019 | | 2019 |
In vitro myeloid differentiation using a new generation of potent human dihydroorotate dehydrogenase (hDHODH) inhibitors S Sainas, AC Pippione, D Bonanni, M Giorgis, E Lupino, E Giraudo, ... Italian-Spanish-Portuguese Joint Meeting in Medicinal Chemistry …, 2018 | | 2018 |