Chemical predictive modelling to improve compound quality JG Cumming, AM Davis, S Muresan, M Haeberlein, H Chen Nature reviews Drug discovery 12 (12), 948-962, 2013 | 306 | 2013 |
The total synthesis of swinholide A. Part 2: A stereocontrolled synthesis of a c1–c15 segment I Paterson, JD Smith, RA Ward Tetrahedron 51 (34), 9413-9436, 1995 | 171 | 1995 |
Heterocyclic compounds useful as pharmaceutical agents D Waterson, ESE Stokes, GR Brown, JG Cumming, NJ Newcombe, ... US Patent 6,313,127, 2001 | 111 | 2001 |
The total synthesis of swinholide A. Part 4: Synthesis of swinholide A and isoswinholide A from the protected monomeric seco acid, pre-swinholide A I Paterson, KS Yeung, RA Ward, JD Smith, JG Cuimming, S Lamboley Tetrahedron 51 (34), 9467-9486, 1995 | 102 | 1995 |
Total synthesis of swinholide A and hemiswinholide A I Paterson, KS Yeung, RA Ward, JG Cumming, JD Smith Journal of the American Chemical Society 116 (20), 9391-9392, 1994 | 97 | 1994 |
Subcutaneous calcium heparin versus intravenous sodium heparin in treatment of established acute deep vein thrombosis of the legs: a multicentre prospective randomised trial. MG Walker, JW Shaw, GJ Thomson, JG Cumming, ML Thomas Br Med J (Clin Res Ed) 294 (6581), 1189-1192, 1987 | 79 | 1987 |
Novel, potent and selective anilinoquinazoline and anilinopyrimidine inhibitors of p38 MAP kinase JG Cumming, CL McKenzie, SG Bowden, D Campbell, DJ Masters, ... Bioorganic & medicinal chemistry letters 14 (21), 5389-5394, 2004 | 76 | 2004 |
Studies in marine macrolide synthesis: Boron and silicon-mediated coupling strategies for Swinholide A I Paterson, JG Cumming, JD Smith, RA Ward Tetrahedron letters 35 (3), 441-444, 1994 | 74 | 1994 |
Pharmaceutically active piperidine derivatives, in particular as modulators of chemokine receptor activity J Burrows, A Cooper, J Cumming, T McInally, H Tucker US Patent App. 10/276,430, 2004 | 73 | 2004 |
Synthesis and antiviral evaluation of enantiomeric 2′, 3′-dideoxy-and 2′, 3′-didehydro-2′, 3′-dideoxy-4′-thionucleosides RJ Young, S Shaw-Ponter, JB Thomson, JA Miller, JG Cumming, ... Bioorganic & Medicinal Chemistry Letters 5 (22), 2599-2604, 1995 | 70 | 1995 |
The total synthesis of swinholide A. Part 3: A stereocontrolled synthesis of (−)-pre-swinholide A. I Paterson, RA Ward, JD Smith, JG Cumming, KS Yeung Tetrahedron 51 (34), 9437-9466, 1995 | 66 | 1995 |
Modulators of the human CCR5 receptor. Part 1: Discovery and initial SAR of 1-(3, 3-diphenylpropyl)-piperidinyl amides and ureas JN Burrows, JG Cumming, SM Fillery, GA Hamlin, JA Hudson, RJ Jackson, ... Bioorganic & medicinal chemistry letters 15 (1), 25-28, 2005 | 58 | 2005 |
Substituted anilino-quinazoline (or quinoline) compounds and use thereof JG Cumming, A AB, Morgan, L Bockius LLP, RL Raymond, TN Truong US Patent 6,593,333, 2003 | 57 | 2003 |
A stereocontrolled synthesis of a C19-C32/C17-C30 Segment for swinholide A and misakinolide A, Cytotoxic dimeric macrolides from theonella swinhoei. I Paterson, JG Cumming Tetrahedron letters 33 (20), 2847-2850, 1992 | 53 | 1992 |
Dynamically resolved peri-substituted 2-formyl naphthamides: a new class of atropisomeric chiral auxiliary J Clayden, C McCarthy, JG Cumming Tetrahedron Letters 41 (18), 3279-3283, 2000 | 52 | 2000 |
Total Synthesis of (-)-Preswinholide A I Paterson, JD Smith, RA Ward, JG Cumming Journal of the American Chemical Society 116 (6), 2615-2616, 1994 | 50 | 1994 |
Automated QSAR with a hierarchy of global and local models DJ Wood, D Buttar, JG Cumming, AM Davis, U Norinder, SL Rodgers Molecular informatics 30 (11‐12), 960-972, 2011 | 45 | 2011 |
Stereocontrolled assembly of tetrasubstituted tetrahydrofurans: a concise synthesis of virgatusin T Akindele, SP Marsden, JG Cumming Organic Letters 7 (17), 3685-3688, 2005 | 44 | 2005 |
Towards the synthesis of swinholide A and scytophycin C. A highly stereocontrolled synthesis of (−)-pre-swinholide A I Paterson, JG Cumming, JD Smith, RA Ward, KS Yeung Tetrahedron letters 35 (20), 3405-3408, 1994 | 43 | 1994 |
Modulators of the human CCR5 receptor. Part 2: SAR of substituted 1-(3, 3-diphenylpropyl)-piperidinyl phenylacetamides JG Cumming, AE Cooper, K Grime, CJ Logan, S McLaughlin, J Oldfield, ... Bioorganic & medicinal chemistry letters 15 (22), 5012-5015, 2005 | 33 | 2005 |