| The glutamate dehydrogenase pathway and its roles in cell and tissue biology in health and disease A Plaitakis, E Kalef-Ezra, D Kotzamani, I Zaganas, C Spanaki Biology 6 (1), 11, 2017 | 219 | 2017 |
| Linking pesticide exposure and dementia: what is the evidence? I Zaganas, S Kapetanaki, V Mastorodemos, K Kanavouras, C Colosio, ... Toxicology 307, 3-11, 2013 | 206 | 2013 |
| Regulation of human glutamate dehydrogenases: implications for glutamate, ammonia and energy metabolism in brain A Plaitakis, I Zaganas Journal of Neuroscience Research 66 (5), 899-908, 2001 | 140 | 2001 |
| Eplontersen for hereditary transthyretin amyloidosis with polyneuropathy T Coelho, W Marques, NR Dasgupta, CC Chao, Y Parman, MC França, ... Jama 330 (15), 1448-1458, 2023 | 87 | 2023 |
| Molecular basis of human glutamate dehydrogenase regulation under changing energy demands V Mastorodemos, I Zaganas, C Spanaki, M Bessa, A Plaitakis Journal of neuroscience research 79 (1‐2), 65-73, 2005 | 85 | 2005 |
| Human GLUD2 glutamate dehydrogenase is expressed in neural and testicular supporting cells C Spanaki, I Zaganas, KA Kleopa, A Plaitakis Journal of Biological Chemistry 285 (22), 16748-16756, 2010 | 81 | 2010 |
| Study of structure–function relationships in human glutamate dehydrogenases reveals novel molecular mechanisms for the regulation of the nerve tissue-specific (GLUD2) isoenzyme A Plaitakis, C Spanaki, V Mastorodemos, I Zaganas Neurochemistry international 43 (4-5), 401-410, 2003 | 76 | 2003 |
| Human GLUD1 and GLUD2 glutamate dehydrogenase localize to mitochondria and endoplasmic reticulum V Mastorodemos, D Kotzamani, I Zaganas, G Arianoglou, H Latsoudis, ... Biochemistry and cell biology 87 (3), 505-516, 2009 | 68 | 2009 |
| Differential expression of glutamate dehydrogenase in cultured neurons and astrocytes from mouse cerebellum and cerebral cortex I Zaganas, HS Waagepetersen, P Georgopoulos, U Sonnewald, ... Journal of neuroscience research 66 (5), 909-913, 2001 | 63 | 2001 |
| Gain-of-function variant in GLUD2 glutamate dehydrogenase modifies Parkinson's disease onset A Plaitakis, H Latsoudis, K Kanavouras, B Ritz, JM Bronstein, I Skoula, ... European journal of human genetics 18 (3), 336-341, 2010 | 61 | 2010 |
| Cerebrospinal fluid TAR DNA-binding protein 43 combined with tau proteins as a candidate biomarker for amyotrophic lateral sclerosis and frontotemporal dementia spectrum disorders M Bourbouli, M Rentzos, A Bougea, V Zouvelou, VC Constantinides, ... Dementia and Geriatric Cognitive Disorders 44 (3-4), 144-152, 2017 | 60 | 2017 |
| Single amino acid substitution (G456A) in the vicinity of the GTP binding domain of human housekeeping glutamate dehydrogenase markedly attenuates GTP inhibition and abolishes … I Zaganas, A Plaitakis Journal of Biological Chemistry 277 (29), 26422-26428, 2002 | 58 | 2002 |
| Age-related decline in verbal learning is moderated by demographic factors, working memory capacity, and presence of amnestic mild cognitive impairment F Constantinidou, I Zaganas, E Papastefanakis, D Kasselimis, A Nidos, ... Journal of the International Neuropsychological Society 20 (8), 822-835, 2014 | 56 | 2014 |
| Associations between sleep duration and cognitive impairment in mild cognitive impairment M Basta, P Simos, A Vgontzas, E Koutentaki, S Tziraki, I Zaganas, ... Journal of Sleep Research 28 (6), e12864, 2019 | 55 | 2019 |
| Myelin content changes in probable Alzheimer's disease and mild cognitive impairment: associations with age and severity of neuropsychiatric impairment E Kavroulakis, PG Simos, G Kalaitzakis, TG Maris, D Karageorgou, ... Journal of Magnetic Resonance Imaging 47 (5), 1359-1372, 2018 | 53 | 2018 |
| Substitution of Ser for Arg-443 in the regulatory domain of human housekeeping (GLUD1) glutamate dehydrogenase virtually abolishes basal activity and markedly alters the … I Zaganas, C Spanaki, M Karpusas, A Plaitakis Journal of Biological Chemistry 277 (48), 46552-46558, 2002 | 50 | 2002 |
| Expression of human GLUD2 glutamate dehydrogenase in human tissues: functional implications I Zaganas, C Spanaki, A Plaitakis Neurochemistry international 61 (4), 455-462, 2012 | 42 | 2012 |
| Peptide EphB2/CTF2 generated by the γ-secretase processing of EphB2 receptor promotes tyrosine phosphorylation and cell surface localization of N-Methyl-d-aspartate receptors J Xu, C Litterst, A Georgakopoulos, I Zaganas, NK Robakis Journal of Biological Chemistry 284 (40), 27220-27228, 2009 | 41 | 2009 |
| Interaction between glutamate dehydrogenase (GDH) and L-leucine catabolic enzymes: intersecting metabolic pathways SM Hutson, MM Islam, I Zaganas Neurochemistry international 59 (4), 518-524, 2011 | 39 | 2011 |
| Expression of the human isoform of glutamate dehydrogenase, hGDH2, augments TCA cycle capacity and oxidative metabolism of glutamate during glucose deprivation in astrocytes JD Nissen, K Lykke, J Bryk, MH Stridh, I Zaganas, DM Skytt, A Schousboe, ... Glia 65 (3), 474-488, 2017 | 38 | 2017 |