| Multiplexed profiling of single extracellular vesicles K Lee, K Fraser, B Ghaddar, K Yang, E Kim, L Balaj, EA Chiocca, ... ACS nano 12 (1), 494-503, 2018 | 332 | 2018 |
| Trial of cinpanemab in early Parkinson’s disease AE Lang, AD Siderowf, EA Macklin, W Poewe, DJ Brooks, HH Fernandez, ... New England Journal of Medicine 387 (5), 408-420, 2022 | 250 | 2022 |
| LRRK2 levels in immune cells are increased in Parkinson’s disease DA Cook, GT Kannarkat, AF Cintron, LM Butkovich, KB Fraser, J Chang, ... NPJ Parkinson's disease 3 (1), 11, 2017 | 241 | 2017 |
| Leucine-rich repeat kinase 2 (LRRK2) pharmacological inhibition abates α-synuclein gene-induced neurodegeneration JPL Daher, HA Abdelmotilib, X Hu, LA Volpicelli-Daley, MS Moehle, ... Journal of Biological Chemistry 290 (32), 19433-19444, 2015 | 227 | 2015 |
| G2019S-LRRK2 expression augments α-synuclein sequestration into inclusions in neurons LA Volpicelli-Daley, H Abdelmotilib, Z Liu, L Stoyka, JPL Daher, ... Journal of Neuroscience 36 (28), 7415-7427, 2016 | 208 | 2016 |
| Ser (P)‐1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson's disease KB Fraser, AB Rawlins, RG Clark, RN Alcalay, DG Standaert, N Liu, ... Movement Disorders 31 (10), 1543-1550, 2016 | 187 | 2016 |
| LRRK2 secretion in exosomes is regulated by 14-3-3 KB Fraser, MS Moehle, JPL Daher, PJ Webber, JY Williams, CA Stewart, ... Human molecular genetics 22 (24), 4988-5000, 2013 | 186 | 2013 |
| α-Synuclein fibril-induced inclusion spread in rats and mice correlates with dopaminergic Neurodegeneration H Abdelmotilib, T Maltbie, V Delic, Z Liu, X Hu, KB Fraser, MS Moehle, ... Neurobiology of disease 105, 84-98, 2017 | 183 | 2017 |
| The influence of computer monitor height on head and neck posture R Burgess-Limerick, A Plooy, K Fraser, DR Ankrum International journal of industrial ergonomics 23 (3), 171-179, 1999 | 155 | 1999 |
| Urinary LRRK2 phosphorylation predicts parkinsonian phenotypes in G2019S LRRK2 carriers KB Fraser, MS Moehle, RN Alcalay, AB West, LRRK2 Cohort Consortium, ... Neurology 86 (11), 994-999, 2016 | 138 | 2016 |
| Integrated kidney exosome analysis for the detection of kidney transplant rejection J Park, HY Lin, JP Assaker, S Jeong, CH Huang, A Kurdi, K Lee, K Fraser, ... ACS nano 11 (11), 11041-11046, 2017 | 131 | 2017 |
| O-GlcNAcylation of AMPA receptor GluA2 is associated with a novel form of long-term depression at hippocampal synapses EW Taylor, K Wang, AR Nelson, TM Bredemann, KB Fraser, SM Clinton, ... Journal of Neuroscience 34 (1), 10-21, 2014 | 121 | 2014 |
| Characterization of single microvesicles in plasma from glioblastoma patients K Fraser, A Jo, J Giedt, C Vinegoni, KS Yang, P Peruzzi, EA Chiocca, ... Neuro-oncology 21 (5), 606-615, 2019 | 100 | 2019 |
| Toll-like receptor 4 engagement mediates prolyl endopeptidase release from airway epithelia via exosomes T Szul, PE Bratcher, KB Fraser, M Kong, R Tirouvanziam, S Ingersoll, ... American journal of respiratory cell and molecular biology 54 (3), 359-369, 2016 | 73 | 2016 |
| Physical and molecular landscapes of mouse glioma extracellular vesicles define heterogeneity A Gyuris, J Navarrete-Perea, A Jo, S Cristea, S Zhou, K Fraser, Z Wei, ... Cell reports 27 (13), 3972-3987. e6, 2019 | 65 | 2019 |
| LRRK2 inhibition by BIIB122 in healthy participants and patients with Parkinson's disease D Jennings, S Huntwork‐Rodriguez, MFJM Vissers, VM Daryani, D Diaz, ... Movement Disorders 38 (3), 386-398, 2023 | 45 | 2023 |
| Unique functional and structural properties of the LRRK2 protein ATP-binding pocket Z Liu, RA Galemmo, KB Fraser, MS Moehle, S Sen, LA Volpicelli-Daley, ... Journal of Biological Chemistry 289 (47), 32937-32951, 2014 | 44 | 2014 |
| Glucocerebrosidase activity is not associated with Parkinson's disease risk or severity N Omer, N Giladi, T Gurevich, A Bar‐Shira, M Gana‐Weisz, T Glinka, ... Movement Disorders 37 (1), 190-195, 2022 | 37 | 2022 |
| Parkinson’s Disease Biomarker Program Consortium; West, AB Ser (P)-1292 LRRK2 in urinary exosomes is elevated in idiopathic Parkinson’s disease KB Fraser, AB Rawlins, RG Clark, RN Alcalay, DG Standaert, N Liu Mov. Disord 31, 1543-1550, 2016 | 33 | 2016 |
| Cinpanemab in early Parkinson disease: evaluation of biomarker results from the phase 2 SPARK clinical trial RM Hutchison, K Fraser, M Yang, T Fox, E Hirschhorn, E Njingti, D Scott, ... Neurology 102 (5), e209137, 2024 | 9 | 2024 |
