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Hyun-Sik Yang
Hyun-Sik Yang
Assitant Professor of Neurology; Brigham and Women's Hospital, Harvard Medical School
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The impact of amyloid‐beta and tau on prospective cognitive decline in older individuals
RA Sperling, EC Mormino, AP Schultz, RA Betensky, KV Papp, ...
Annals of neurology 85 (2), 181-193, 2019
2672019
Interactive associations of vascular risk and β-amyloid burden with cognitive decline in clinically normal elderly individuals: findings from the Harvard Aging Brain Study
JS Rabin, AP Schultz, T Hedden, A Viswanathan, GA Marshall, ...
JAMA neurology 75 (9), 1124-1131, 2018
2262018
Neurogenetic contributions to amyloid beta and tau spreading in the human cortex
J Sepulcre, MJ Grothe, F d’Oleire Uquillas, L Ortiz-Terán, I Diez, HS Yang, ...
Nature medicine 24 (12), 1910-1918, 2018
1822018
Associations of physical activity and β-amyloid with longitudinal cognition and neurodegeneration in clinically normal older adults
JS Rabin, H Klein, DR Kirn, AP Schultz, HS Yang, O Hampton, S Jiang, ...
JAMA neurology 76 (10), 1203-1210, 2019
1432019
Evaluation of TDP-43 proteinopathy and hippocampal sclerosis in relation to APOE ε4 haplotype status: a community-based cohort study
HS Yang, L Yu, CC White, LB Chibnik, JP Chhatwal, RA Sperling, ...
The Lancet Neurology 17 (9), 773-781, 2018
1282018
Genetic variants and functional pathways associated with resilience to Alzheimer’s disease
L Dumitrescu, ER Mahoney, S Mukherjee, ML Lee, WS Bush, ...
Brain 143 (8), 2561-2575, 2020
1212020
Longitudinal Association of Depression Symptoms With Cognition and Cortical Amyloid Among Community-Dwelling Older Adults
JR Gatchel, JS Rabin, RF Buckley, JJ Locascio, YT Quiroz, HS Yang, ...
JAMA Network Open 2 (8), e198964-e198964, 2019
1142019
Vascular Risk and β‐Amyloid Are Synergistically Associated with Cortical Tau
JS Rabin, HS Yang, AP Schultz, BJ Hanseeuw, T Hedden, A Viswanathan, ...
Annals of neurology 85 (2), 272-279, 2019
1032019
Identification of genes associated with dissociation of cognitive performance and neuropathological burden: Multistep analysis of genetic, epigenetic, and transcriptional data
CC White, HS Yang, L Yu, LB Chibnik, RJ Dawe, J Yang, HU Klein, ...
PLoS medicine 14 (4), e1002287, 2017
942017
Use of angiotensin-converting-enzyme inhibitors or angiotensin-receptor blockers and cancer risk: a meta-analysis of observational studies
C Yoon, HS Yang, I Jeon, Y Chang, SM Park
Cmaj 183 (14), E1073-E1084, 2011
932011
LATE-NC staging in routine neuropathologic diagnosis: an update
PT Nelson, EB Lee, MD Cykowski, I Alafuzoff, K Arfanakis, J Attems, ...
Acta neuropathologica 145 (2), 159-173, 2023
902023
Effect of obesity on survival of women with epithelial ovarian cancer: a systematic review and meta-analysis of observational studies
HS Yang, C Yoon, SK Myung, SM Park
International Journal of Gynecologic Cancer 21 (9), 2011
902011
Characterization of mitochondrial DNA quantity and quality in the human aged and Alzheimer’s disease brain
HU Klein, C Trumpff, HS Yang, AJ Lee, M Picard, DA Bennett, ...
Molecular neurodegeneration 16 (1), 1-17, 2021
862021
Multicellular communities are perturbed in the aging human brain and Alzheimer’s disease
A Cain, M Taga, C McCabe, GS Green, I Hekselman, CC White, DI Lee, ...
Nature Neuroscience, 1-14, 2023
852023
Association of elevated amyloid and tau positron emission tomography signal with near-term development of Alzheimer disease symptoms in older adults without cognitive impairment
C Strikwerda-Brown, DA Hobbs, J Gonneaud, F St-Onge, AP Binette, ...
JAMA neurology 79 (10), 975-985, 2022
772022
Plasma IL‐12/IFN‐γ axis predicts cognitive trajectories in cognitively unimpaired older adults
HS Yang, C Zhang, BC Carlyle, SY Zhen, BA Trombetta, AP Schultz, ...
Alzheimer's & Dementia 18 (4), 645-653, 2022
732022
Association between common variants in RBFOX1, an RNA-binding protein, and brain amyloidosis in early and preclinical Alzheimer disease
NS Raghavan, L Dumitrescu, E Mormino, ER Mahoney, AJ Lee, Y Gao, ...
JAMA neurology 77 (10), 1288-1298, 2020
652020
Plasma N-terminal tau fragment levels predict future cognitive decline and neurodegeneration in healthy elderly individuals
JP Chhatwal, AP Schultz, Y Dang, B Ostaszewski, L Liu, HS Yang, ...
Nature Communications 11 (1), 6024, 2020
592020
The rubrospinal tract in the human brain: diffusion tensor imaging study
HS Yang, HG Kwon, JH Hong, CP Hong, SH Jang
Neuroscience letters 504 (1), 45-48, 2011
552011
Sex differences in the genetic architecture of cognitive resilience to Alzheimer’s disease
JM Eissman, L Dumitrescu, ER Mahoney, AN Smith, S Mukherjee, ML Lee, ...
Brain 145 (7), 2541-2554, 2022
532022
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