In vivo detection of diffuse inflammation in secondary progressive multiple sclerosis using PET imaging and the radioligand 11C-PK11195 E Rissanen, J Tuisku, J Rokka, T Paavilainen, R Parkkola, JO Rinne, ... Journal of Nuclear Medicine 55 (6), 939-944, 2014 | 191 | 2014 |
Brain TSPO-PET predicts later disease progression independent of relapses in multiple sclerosis M Sucksdorff, M Matilainen, J Tuisku, E Polvinen, A Vuorimaa, J Rokka, ... Brain 143 (11), 3318-3330, 2020 | 130 | 2020 |
Interindividual variability and lateralization of μ-opioid receptors in the human brain T Kantonen, T Karjalainen, J Isojärvi, P Nuutila, J Tuisku, J Rinne, ... NeuroImage 217, 116922, 2020 | 105 | 2020 |
Adenosine A2A receptors in secondary progressive multiple sclerosis: a [11C] TMSX brain PET study E Rissanen, JR Virta, T Paavilainen, J Tuisku, S Helin, P Luoto, ... Journal of Cerebral Blood Flow & Metabolism 33 (9), 1394-1401, 2013 | 102 | 2013 |
Effects of age, BMI and sex on the glial cell marker TSPO — a multicentre [11C]PBR28 HRRT PET study J Tuisku, P Plavén-Sigray, EC Gaiser, L Airas, H Al-Abdulrasul, A Brück, ... European journal of nuclear medicine and molecular imaging 46, 2329-2338, 2019 | 99 | 2019 |
Evaluation of the effect of fingolimod treatment on microglial activation using serial PET imaging in multiple sclerosis M Sucksdorff, E Rissanen, J Tuisku, S Nuutinen, T Paavilainen, J Rokka, ... Journal of Nuclear Medicine 58 (10), 1646-1651, 2017 | 92 | 2017 |
Microglial activation, white matter tract damage, and disability in MS E Rissanen, J Tuisku, T Vahlberg, M Sucksdorff, T Paavilainen, ... Neurology: Neuroimmunology & Neuroinflammation 5 (3), e443, 2018 | 76 | 2018 |
Lowered endogenous mu-opioid receptor availability in subclinical depression and anxiety L Nummenmaa, T Karjalainen, J Isojärvi, T Kantonen, J Tuisku, ... Neuropsychopharmacology 45 (11), 1953-1959, 2020 | 72 | 2020 |
Natalizumab treatment reduces microglial activation in the white matter of the MS brain M Sucksdorff, J Tuisku, M Matilainen, A Vuorimaa, S Smith, J Keitilä, ... Neurology: Neuroimmunology & Neuroinflammation 6 (4), e574, 2019 | 61 | 2019 |
Magia: robust automated image processing and kinetic modeling toolbox for PET neuroinformatics T Karjalainen, J Tuisku, S Santavirta, T Kantonen, M Bucci, L Tuominen, ... Frontiers in neuroinformatics 14, 3, 2020 | 58 | 2020 |
Automated Reference Region Extraction and Population-Based Input Function for Brain [11C]TMSX PET Image Analyses E Rissanen, J Tuisku, P Luoto, E Arponen, J Johansson, V Oikonen, ... Journal of Cerebral Blood Flow & Metabolism 35 (1), 157-165, 2015 | 51 | 2015 |
Intranasal naloxone rapidly occupies brain mu-opioid receptors in human subjects J Johansson, J Hirvonen, Z Lovró, L Ekblad, V Kaasinen, O Rajasilta, ... Neuropsychopharmacology 44 (9), 1667-1673, 2019 | 47 | 2019 |
Association of Early β-Amyloid Accumulation and Neuroinflammation Measured With [11C]PBR28 in Elderly Individuals Without Dementia S Toppala, LL Ekblad, J Tuisku, S Helin, JJ Johansson, H Laine, ... Neurology 96 (12), e1608-e1619, 2021 | 40 | 2021 |
Insights into disseminated MS brain pathology with multimodal diffusion tensor and PET imaging S Bezukladova, J Tuisku, M Matilainen, A Vuorimaa, M Nylund, S Smith, ... Neurology: Neuroimmunology & Neuroinflammation 7 (3), e691, 2020 | 37 | 2020 |
High serum neurofilament associates with diffuse white matter damage in MS M Saraste, S Bezukladova, M Matilainen, J Tuisku, E Rissanen, ... Neurology: Neuroimmunology & Neuroinflammation 8 (1), e926, 2020 | 36 | 2020 |
Phenotyping of multiple sclerosis lesions according to innate immune cell activation using 18 kDa translocator protein-PET M Nylund, M Sucksdorff, M Matilainen, E Polvinen, J Tuisku, L Airas Brain Communications 4 (1), fcab301, 2022 | 33 | 2022 |
Elevated serum chemokine CCL22 levels in first-episode psychosis: associations with symptoms, peripheral immune state and in vivo brain glial cell function H Laurikainen, A Vuorela, A Toivonen, L Reinert-Hartwall, K Trontti, ... Translational Psychiatry 10 (1), 94, 2020 | 21 | 2020 |
Quantitative perfusion imaging with total-body PET J Knuuti, J Tuisku, H Kärpijoki, H Iida, T Maaniitty, A Latva-Rasku, ... Journal of Nuclear Medicine 64 (Supplement 2), 11S-19S, 2023 | 15 | 2023 |
APOE ε4 gene dose effect on imaging and blood biomarkers of neuroinflammation and beta-amyloid in cognitively unimpaired elderly A Snellman, LL Ekblad, J Tuisku, M Koivumäki, NJ Ashton, ... Alzheimer's Research & Therapy 15 (1), 71, 2023 | 15 | 2023 |
18F-Labeling of Mannan for Inflammation Research with Positron Emission Tomography XG Li, C Hagert, R Siitonen, H Virtanen, O Sareila, H Liljenback, J Tuisku, ... ACS Medicinal Chemistry Letters 7 (9), 826-830, 2016 | 15 | 2016 |