| Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan KT Howitz, KJ Bitterman, HY Cohen, DW Lamming, S Lavu, JG Wood, ... Nature 425 (6954), 191-196, 2003 | 4940 | 2003 |
| Rapamycin-induced insulin resistance is mediated by mTORC2 loss and uncoupled from longevity DW Lamming, L Ye, P Katajisto, MD Goncalves, M Saitoh, DM Stevens, ... Science 335 (6076), 1638, 2012 | 1377 | 2012 |
| Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival H Yang, T Yang, JA Baur, E Perez, T Matsui, JJ Carmona, DW Lamming, ... Cell 130 (6), 1095-1107, 2007 | 1140 | 2007 |
| High-fat diet enhances stemness and tumorigenicity of intestinal progenitors S Beyaz, MD Mana, J Roper, D Kedrin, A Saadatpour, SJ Hong, ... Nature 531 (7592), 53-58, 2016 | 823 | 2016 |
| mTORC1 in the Paneth cell niche couples intestinal stem-cell function to calorie intake ÖH Yilmaz, P Katajisto, DW Lamming, Y Gültekin, KE Bauer-Rowe, ... Nature 486 (7404), 490-495, 2012 | 813 | 2012 |
| TOR signaling and rapamycin influence longevity by regulating SKN-1/Nrf and DAF-16/FoxO S Robida-Stubbs, K Glover-Cutter, DW Lamming, M Mizunuma, ... Cell metabolism 15 (5), 713-724, 2012 | 766 | 2012 |
| Evidence for a Common Mechanism of SIRT1 Regulation by Allosteric Activators BP Hubbard, AP Gomes, H Dai, J Li, AW Case, T Considine, TV Riera, ... Science 339 (6124), 1216-1219, 2013 | 670 | 2013 |
| The TSC-mTOR pathway regulates macrophage polarization V Byles, AJ Covarrubias, I Ben-Sahra, DW Lamming, DM Sabatini, ... Nature communications 4 (1), 2834, 2013 | 626 | 2013 |
| Rapalogs and mTOR inhibitors as anti-aging therapeutics DW Lamming, L Ye, DM Sabatini, JA Baur The Journal of clinical investigation 123 (3), 980-989, 2013 | 615 | 2013 |
| The mechanistic target of rapamycin: the grand conducTOR of metabolism and aging BK Kennedy, DW Lamming Cell metabolism 23 (6), 990-1003, 2016 | 557 | 2016 |
| Molecular mechanisms of dietary restriction promoting health and longevity CL Green, DW Lamming, L Fontana Nature Reviews Molecular Cell Biology 23 (1), 56-73, 2022 | 513 | 2022 |
| Decreased consumption of branched-chain amino acids improves metabolic health L Fontana, NE Cummings, SIA Apelo, JC Neuman, I Kasza, BA Schmidt, ... Cell reports 16 (2), 520-530, 2016 | 459 | 2016 |
| A central role for mTOR in lipid homeostasis DW Lamming, DM Sabatini Cell metabolism 18 (4), 465-469, 2013 | 420 | 2013 |
| Akt-mTORC1 signaling regulates Acly to integrate metabolic input to control of macrophage activation AJ Covarrubias, HI Aksoylar, J Yu, NW Snyder, AJ Worth, SS Iyer, J Wang, ... elife 5, e11612, 2016 | 414 | 2016 |
| MSN2 and MSN4 Link Calorie Restriction and TOR to Sirtuin-Mediated Lifespan Extension in Saccharomyces cerevisiae O Medvedik, DW Lamming, KD Kim, DA Sinclair PLoS biology 5 (10), e261, 2007 | 395 | 2007 |
| Longer lifespan in male mice treated with a weakly estrogenic agonist, an antioxidant, an α‐glucosidase inhibitor or a Nrf2‐inducer R Strong, RA Miller, A Antebi, CM Astle, M Bogue, MS Denzel, ... Aging cell 15 (5), 872-884, 2016 | 350 | 2016 |
| STING senses microbial viability to orchestrate stress-mediated autophagy of the endoplasmic reticulum J Moretti, S Roy, D Bozec, J Martinez, JR Chapman, B Ueberheide, ... Cell 171 (4), 809-823. e13, 2017 | 333 | 2017 |
| Restoration of metabolic health by decreased consumption of branched‐chain amino acids NE Cummings, EM Williams, I Kasza, EN Konon, MD Schaid, BA Schmidt, ... The Journal of physiology 596 (4), 623-645, 2018 | 331 | 2018 |
| Calorie restriction in humans inhibits the PI3K/AKT pathway and induces a younger transcription profile EM Mercken, SD Crosby, DW Lamming, L JeBailey, S Krzysik‐Walker, ... Aging cell 12 (4), 645-651, 2013 | 304 | 2013 |
| The adverse metabolic effects of branched-chain amino acids are mediated by isoleucine and valine D Yu, NE Richardson, CL Green, AB Spicer, ME Murphy, V Flores, C Jang, ... Cell metabolism 33 (5), 905-922. e6, 2021 | 298 | 2021 |
David M. SabatiniInstitute of Organic Chemistry and Biochemistry of the CASuochb.cas.cz의 이메일 확인됨
