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Chiara Falcomatà
Chiara Falcomatà
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Discovery of methylated circulating DNA biomarkers for comprehensive non-invasive monitoring of treatment response in metastatic colorectal cancer
L Barault, A Amatu, G Siravegna, A Ponzetti, S Moran, A Cassingena, ...
Gut 67 (11), 1995-2005, 2018
2342018
Digital PCR quantification of MGMT methylation refines prediction of clinical benefit from alkylating agents in glioblastoma and metastatic colorectal cancer
L Barault, A Amatu, FE Bleeker, C Moutinho, C Falcomatà, V Fiano, ...
Annals of oncology 26 (9), 1994-1999, 2015
1302015
Context-specific determinants of the immunosuppressive tumor microenvironment in pancreatic cancer
C Falcomatà, S Bärthel, G Schneider, R Rad, M Schmidt-Supprian, ...
Cancer Discovery 13 (2), 278-297, 2023
912023
Selective multi-kinase inhibition sensitizes mesenchymal pancreatic cancer to immune checkpoint blockade by remodeling the tumor microenvironment
C Falcomata, S Baerthel, SA Widholz, C Schneeweis, JJ Montero, ...
Nature Cancer 3 (3), 318-336, 2022
802022
Decrypting drug actions and protein modifications by dose-and time-resolved proteomics
J Zecha, FP Bayer, S Wiechmann, J Woortman, N Berner, J Müller, ...
Science 380 (6640), 93-101, 2023
572023
Single-cell profiling to explore pancreatic cancer heterogeneity, plasticity and response to therapy
S Bärthel, C Falcomatà, R Rad, FJ Theis, D Saur
Nature cancer 4 (4), 454-467, 2023
522023
Bromodomain inhibition exerts its therapeutic potential in malignant pleural mesothelioma by promoting immunogenic cell death and changing the tumor immune-environment
C Riganti, MF Lingua, IC Salaroglio, C Falcomatà, L Righi, D Morena, ...
Oncoimmunology 7 (3), e1398874, 2018
512018
Mass spectrometry-based draft of the mouse proteome
P Giansanti, P Samaras, Y Bian, C Meng, A Coluccio, M Frejno, ...
Nature methods 19 (7), 803-811, 2022
442022
Digital PCR assessment of MGMT promoter methylation coupled with reduced protein expression optimises prediction of response to alkylating agents in metastatic colorectal …
A Sartore-Bianchi, F Pietrantonio, A Amatu, M Milione, A Cassingena, ...
European Journal of Cancer 71, 43-50, 2017
362017
Pancreatic cancer intrinsic PI3Kα activity accelerates metastasis and rewires macrophage component
B Thibault, F Ramos‐Delgado, E Pons‐Tostivint, N Therville, C Cintas, ...
EMBO molecular medicine 13 (7), e13502, 2021
312021
CRISPR somatic genome engineering and cancer modeling in the mouse pancreas and liver
T Kaltenbacher, J Löprich, R Maresch, J Weber, S Müller, R Oellinger, ...
Nature Protocols 17 (4), 1142-1188, 2022
212022
Genetic Screens Identify a Context-Specific PI3K/p27Kip1 Node Driving Extrahepatic Biliary Cancer
C Falcomatà, S Bärthel, A Ulrich, S Diersch, C Veltkamp, L Rad, F Boniolo, ...
Cancer discovery 11 (12), 3158-3177, 2021
202021
Hematopoietic aging promotes cancer by fueling IL-1⍺–driven emergency myelopoiesis
MD Park, J Le Berichel, P Hamon, CM Wilk, M Belabed, N Yatim, A Saffon, ...
Science 386 (6720), eadn0327, 2024
182024
Non-canonical functions of SNAIL drive context-specific cancer progression
MC Paul, C Schneeweis, C Falcomatà, C Shan, D Rossmeisl, S Koutsouli, ...
Nature Communications 14 (1), 1201, 2023
182023
Cell-selective proteomics segregates pancreatic cancer subtypes by extracellular proteins in tumors and circulation
JJ Swietlik, S Bärthel, C Falcomatà, D Fink, A Sinha, J Cheng, S Ebner, ...
Nature Communications 14 (1), 2642, 2023
132023
AP1/Fra1 confers resistance to MAPK cascade inhibition in pancreatic cancer
C Schneeweis, S Diersch, Z Hassan, L Krauß, C Schneider, D Lucarelli, ...
Cellular and Molecular Life Sciences 80 (1), 12, 2023
92023
New insights into pancreatic cancer: notes from a virtual meeting
E Hessmann, G Schneider, C Bousquet, C Der, S Dreyer, N Dusetti, ...
Gastroenterology 161 (3), 785-791, 2021
62021
Personalizing KRAS-Mutant Allele–Specific Therapies
C Falcomatà, G Schneider, D Saur
Cancer Discovery 10 (1), 23-25, 2020
62020
Ovarian cancer-derived IL-4 promotes immunotherapy resistance
G Mollaoglu, A Tepper, C Falcomatà, HT Potak, L Pia, A Amabile, ...
Cell 187 (26), 7492-7510. e22, 2024
42024
Dual Recombinase–Based Mouse Models Help Decipher Cancer Biology and Targets for Therapy
T Sket, C Falcomatà, D Saur
Cancer Research 83 (14), 2279-2282, 2023
42023
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