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Charles J. Norsigian
Charles J. Norsigian
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BiGG Models 2020: multi-strain genome-scale models and expansion across the phylogenetic tree
CJ Norsigian, N Pusarla, JL McConn, JT Yurkovich, A Dräger, BO Palsson, ...
Nucleic acids research 48 (D1), D402-D406, 2020
2432020
A workflow for generating multi-strain genome-scale metabolic models of prokaryotes
CJ Norsigian, X Fang, Y Seif, JM Monk, BO Palsson
Nature protocols 15 (1), 1-14, 2020
752020
Updated and standardized genome-scale reconstruction of Mycobacterium tuberculosis H37Rv, iEK1011, simulates flux states indicative of physiological conditions
ES Kavvas, Y Seif, JT Yurkovich, C Norsigian, S Poudel, WW Greenwald, ...
BMC systems biology 12, 1-15, 2018
612018
Functional annotation of enzyme-encoding genes using deep learning with transformer layers
GB Kim, JY Kim, JA Lee, CJ Norsigian, BO Palsson, SY Lee
Nature Communications 14 (1), 7370, 2023
502023
iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of Acinetobacter baumannii AYE
CJ Norsigian, E Kavvas, Y Seif, BO Palsson, JM Monk
Frontiers in Genetics 9, 121, 2018
432018
Comparative Genome-Scale Metabolic Modeling of Metallo-Beta-Lactamase–Producing Multidrug-Resistant Klebsiella pneumoniae Clinical Isolates
CJ Norsigian, H Attia, R Szubin, AS Yassin, BØ Palsson, RK Aziz, ...
Frontiers in cellular and infection microbiology 9, 161, 2019
342019
Systems biology analysis of the Clostridioides difficile core-genome contextualizes microenvironmental evolutionary pressures leading to genotypic and phenotypic …
CJ Norsigian, HA Danhof, CK Brand, N Oezguen, FS Midani, BO Palsson, ...
NPJ systems biology and applications 6 (1), 31, 2020
252020
Reconstruction and Validation of a Genome-Scale Metabolic Model of Streptococcus oralis (iCJ415), a Human Commensal and Opportunistic Pathogen
CS Jensen, CJ Norsigian, X Fang, XC Nielsen, JJ Christensen, ...
Frontiers in Genetics 11, 116, 2020
162020
Pangenome flux balance analysis toward panphenomes
CJ Norsigian, X Fang, BO Palsson, JM Monk
The pangenome: diversity, dynamics and evolution of genomes, 219-232, 2020
162020
Systems biology approach to functionally assess the Clostridioides difficile pangenome reveals genetic diversity with discriminatory power
CJ Norsigian, HA Danhof, CK Brand, FS Midani, JT Broddrick, ...
Proceedings of the National Academy of Sciences 119 (18), e2119396119, 2022
112022
Mathematical models to study the biology of pathogens and the infectious diseases they cause
JB Xavier, JM Monk, S Poudel, CJ Norsigian, AV Sastry, C Liao, J Bento, ...
Iscience 25 (4), 2022
112022
The pangenome: diversity, dynamics and evolution of genomes
CJ Norsigian, X Fang, BO Palsson, JM Monk, H Tettelin, D Medini
Springer, 2020
82020
High-quality genome-scale models from error-prone, long-read assemblies
JT Broddrick, R Szubin, CJ Norsigian, JM Monk, BO Palsson, ...
Frontiers in Microbiology 11, 596626, 2020
32020
DeepECtransformer: A Transformer-based Deep Learning Model for Enzyme Function Prediction
GB KIM, JY KIM, JA LEE, CJ NORSIGIAN, BO PALSSON, W Ziling, ...
한국생물공학회 학술대회, 509-509, 2024
2024
Deep Learning Approach for Functional Annotation of Enzyme-encoding Genes
GB KIM, JY KIM, JA LEE, CJ NORSIGIAN, BO PALSSON, SY LEE
한국생물공학회 학술대회, 249-249, 2024
2024
Functional Annotation of Enzyme Encoding Genes Using Deep Learning
GB KIM, JY KIM, JA LEE, CJ NORSIGIAN, BO PALSSON, SY LEE
한국생물공학회 학술대회, 707-707, 2023
2023
Pan-Genome Enriched Analytics: Systems Biology Examination of the Diversity of Microbial Pathogens
CJ Norsigian
University of California, San Diego, 2021
2021
iCN718, an Updated and Improved Genome-Scale Metabolic Network Reconstruction of
CJ Norsigian, E Kavvas, Y Seif
2018
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