| Widespread intron retention in mammals functionally tunes transcriptomes U Braunschweig, NL Barbosa-Morais, Q Pan, EN Nachman, B Alipanahi, ... Genome research 24 (11), 1774-1786, 2014 | 720 | 2014 |
| A highly conserved program of neuronal microexons is misregulated in autistic brains M Irimia, RJ Weatheritt, JD Ellis, NN Parikshak, ... Cell 159 (7), 1511-1523, 2014 | 680 | 2014 |
| Cap-binding complex (CBC) T Gonatopoulos-Pournatzis, VH Cowling Biochemical Journal 457 (2), 231-242, 2014 | 247 | 2014 |
| Multilayered Control of Alternative Splicing Regulatory Networks by Transcription Factors H Han, U Braunschweig, T Gonatopoulos-Pournatzis, RJ Weatheritt, ... Molecular Cell 65 (3), 539-553. e7, 2017 | 183 | 2017 |
| An alternative splicing event amplifies evolutionary differences between vertebrates S Gueroussov, T Gonatopoulos-Pournatzis, M Irimia, B Raj, ZY Lin, ... Science 349 (6250), 868-873, 2015 | 164 | 2015 |
| Misregulation of an Activity-Dependent Splicing Network as a Common Mechanism Underlying Autism Spectrum Disorders M Quesnel-Vallières, Z Dargaei, M Irimia, T Gonatopoulos-Pournatzis, ... Molecular Cell 64 (6), 1023-1034, 2016 | 163 | 2016 |
| Genetic interaction mapping and exon-resolution functional genomics with a hybrid Cas9–Cas12a platform T Gonatopoulos-Pournatzis, M Aregger, KR Brown, S Farhangmehr, ... Nature biotechnology 38 (5), 638-648, 2020 | 132 | 2020 |
| Genome-wide CRISPR-Cas9 interrogation of splicing networks reveals a mechanism for recognition of autism-misregulated neuronal microexons T Gonatopoulos-Pournatzis, M Wu, U Braunschweig, J Roth, H Han, ... Molecular cell 72 (3), 510-524. e12, 2018 | 117 | 2018 |
| Autism-misregulated eIF4G microexons control synaptic translation and higher order cognitive functions T Gonatopoulos-Pournatzis, R Niibori, EW Salter, RJ Weatheritt, B Tsang, ... Molecular cell 77 (6), 1176-1192. e16, 2020 | 102 | 2020 |
| RAM/Fam103a1 is required for mRNA cap methylation T Gonatopoulos-Pournatzis, S Dunn, R Bounds, VH Cowling Molecular cell 44 (4), 585-596, 2011 | 95 | 2011 |
| Control of embryonic stem cell self-renewal and differentiation via coordinated alternative splicing and translation of YY2 S Tahmasebi, SM Jafarnejad, IS Tam, T Gonatopoulos-Pournatzis, ... Proceedings of the National Academy of Sciences 113 (44), 12360-12367, 2016 | 82 | 2016 |
| S-adenosyl homocysteine hydrolase is required for Myc-induced mRNA cap methylation, protein synthesis, and cell proliferation ME Fernandez-Sanchez, T Gonatopoulos-Pournatzis, G Preston, ... Molecular and cellular biology, 2009 | 70 | 2009 |
| Microexons: at the nexus of nervous system development, behaviour and autism spectrum disorder T Gonatopoulos-Pournatzis, BJ Blencowe Current Opinion in Genetics & Development 65, 22-33, 2020 | 62 | 2020 |
| Mechanisms of Neuronal Alternative Splicing and Strategies for Therapeutic Interventions EJL Soto, MJ Gandal, T Gonatopoulos-Pournatzis, EA Heller, D Luo, ... Journal of Neuroscience 39 (42), 8193-8199, 2019 | 38 | 2019 |
| mRNA Cap Methylation in Pluripotency and Differentiation L Grasso, O Suska, L Davidson, T Gonatopoulos-Pournatzis, ... Cell Reports 16 (5), 1352-1365, 2016 | 29 | 2016 |
| Systematic exploration of dynamic splicing networks reveals conserved multistage regulators of neurogenesis H Han, AJ Best, U Braunschweig, N Mikolajewicz, JD Li, J Roth, ... Molecular cell 82 (16), 2982-2999. e14, 2022 | 18 | 2022 |
| RAM function is dependent on Kapβ2-mediated nuclear entry T Gonatopoulos-Pournatzis, VH Cowling Biochemical Journal 457 (3), 473-484, 2014 | 18 | 2014 |
| Application of CHyMErA Cas9-Cas12a combinatorial genome-editing platform for genetic interaction mapping and gene fragment deletion screening M Aregger, K Xing, T Gonatopoulos-Pournatzis Nature protocols 16 (10), 4722-4765, 2021 | 13 | 2021 |
| Analysis of combinatorial CRISPR screens with the Orthrus scoring pipeline HN Ward, M Aregger, T Gonatopoulos-Pournatzis, M Billmann, ... Nature protocols 16 (10), 4766-4798, 2021 | 13 | 2021 |
| Genome-scale exon perturbation screens uncover exons critical for cell fitness MS Xiao, AP Damodaran, B Kumari, E Dickson, K Xing, TA On, N Parab, ... Molecular Cell 84 (13), 2553-2572. e19, 2024 | 5 | 2024 |