Staphylococcus aureus induces an itaconate-dominated immunometabolic response that drives biofilm formation KL Tomlinson, TWF Lung, F Dach, MK Annavajhala, SJ Gabryszewski, ... Nature communications 12 (1), 1399, 2021 | 109 | 2021 |
CFTR-PTEN–dependent mitochondrial metabolic dysfunction promotes Pseudomonas aeruginosa airway infection SA Riquelme, C Lozano, AM Moustafa, K Liimatta, KL Tomlinson, C Britto, ... Science translational medicine 11 (499), eaav4634, 2019 | 84 | 2019 |
Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst KL Tomlinson, SA Riquelme, SU Baskota, M Drikic, IR Monk, TP Stinear, ... Cell reports 42 (2), 2023 | 57 | 2023 |
Metabolic Adaptation in Methicillin-Resistant Staphylococcus aureus Pneumonia SJ Gabryszewski, T Wong Fok Lung, MK Annavajhala, KL Tomlinson, ... American Journal of Respiratory Cell and Molecular Biology 61 (2), 185-197, 2019 | 43 | 2019 |
Immunometabolites drive bacterial adaptation to the airway KL Tomlinson, AS Prince, T Wong Fok Lung Frontiers in Immunology 12, 790574, 2021 | 15 | 2021 |
Ketogenesis promotes tolerance to Pseudomonas aeruginosa pulmonary infection KL Tomlinson, YT Chen, A Junker, AC Urso, TWF Lung, D Ahn, ... Cell Metabolism 35 (10), 1767-1781. e6, 2023 | 14 | 2023 |
Host-bacteria metabolic crosstalk drives S. aureus biofilm KL Tomlinson, SA Riquelme Microbial Cell 8 (5), 106, 2021 | 7 | 2021 |
Staphylococcus aureus stimulates neutrophil itaconate production that suppresses the oxidative burst. Cell Rep. 42, 112064 KL Tomlinson, SA Riquelme, SU Baskota, M Drikic, IR Monk, TP Stinear, ... | 5 | 2023 |
In Vivo Adaptation of S. Aureus to the Lung Is Driven by Itaconate, A Mitochondrial Immune Metabolite K Tomlinson, F Dach, SA Riquelme, T Wong, AM Moustafa, PJ Planet, ... D102. BACTERIAL INFECTIONS: IMMUNITY AND BASIC MECHANISMS, A7715-A7715, 2020 | 1 | 2020 |
11 Ketogenesis enables disease tolerance during Pseudomonas aeruginosa pulmonary infection K Tomlinson, Y Chen, C Hofstaedter, R Ernst, A Prince, S Riquelme Journal of Cystic Fibrosis 23, S6, 2024 | | 2024 |
85 Ketogenesis promotes tolerance to Pseudomonas aeruginosa infection in the cystic fibrosis lung K Tomlinson, Y Chen, A Junker, A Urso, T Wong, D Ahn, C Hofstaedter, ... Journal of Cystic Fibrosis 22, S45, 2023 | | 2023 |
The Itaconate-Driven Immunometabolic Response to S. Aureus Promotes Persistent Lung Infection KL Tomlinson Columbia University, 2023 | | 2023 |
526 Pulmonary ketogenesis promotes tolerance to Pseudomonas aeruginosa infection in the cystic fibrosis lung K Tomlinson, Y Chen, A Prince, S Riquelme Journal of Cystic Fibrosis 21, S293-S294, 2022 | | 2022 |
489 Cystic fibrosis airway metabolites contribute to persistent pulmonary infection K Tomlinson, D Fucich, T Wong, S Riquelme, A Prince Journal of Cystic Fibrosis 21, S277, 2022 | | 2022 |
420: Extracellular polysaccharides are metabolo-stimulatory ligands that favor Pseudomonas aeruginosa iron scavenging I Khan, K Tomlinson, B Fields, G Rosenberg, D Yehezkel, K Kim, ... Journal of Cystic Fibrosis 20, S197, 2021 | | 2021 |
STAPHYLOCOCCUS AUREUS PERSISTENCE IN THE LUNG IS DRIVEN BY THE IMMUNE METABOLITE, ITACONATE KL Tomlinson, T Wong, F Dach, M Annavajhala, N Francoeur, SH Sridhar, ... PEDIATRIC PULMONOLOGY 55, S156-S156, 2020 | | 2020 |
CFTR-REGULATED METABOLITES SELECT FOR CF PATHOGENS A Prince, KL Tomlinson, T Wong, SH Sridhar, I Lewis, R Groves, M Smith, ... PEDIATRIC PULMONOLOGY 55, S145-S146, 2020 | | 2020 |
IN VIVO EVOLUTION OF CF STAPHYLOCOCCUS AUREUS STRAINS IN RESPONSE TO IMMUNE CELL SIGNALING METABOLITES F Dach, SA Riquelme, K Tomlinson, K Liimatta, AM Moustafa, PJ Planet, ... PEDIATRIC PULMONOLOGY 54, S310-S311, 2019 | | 2019 |