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Conor M. Henry
Conor M. Henry
Francis Crick Institue, London, UK
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Neutrophil-derived proteases escalate inflammation through activation of IL-36 family cytokines
CM Henry, GP Sullivan, DM Clancy, IS Afonina, D Kulms, SJ Martin
Cell reports 14 (4), 708-722, 2016
3512016
Caspase-8 acts in a non-enzymatic role as a scaffold for assembly of a pro-inflammatory “FADDosome” complex upon TRAIL stimulation
CM Henry, SJ Martin
Molecular cell 65 (4), 715-729. e5, 2017
2622017
Fas/CD95-induced chemokines can serve as “find-me” signals for apoptotic cells
SP Cullen, CM Henry, CJ Kearney, SE Logue, M Feoktistova, GA Tynan, ...
Molecular cell 49 (6), 1034-1048, 2013
2522013
Measuring apoptosis by microscopy and flow cytometry
CM Henry, E Hollville, SJ Martin
Methods 61 (2), 90-97, 2013
2412013
A perspective on mammalian caspases as positive and negative regulators of inflammation
SJ Martin, CM Henry, SP Cullen
Molecular cell 46 (4), 387-397, 2012
2342012
Extracellular neutrophil proteases are efficient regulators of IL-1, IL-33, and IL-36 cytokine activity but poor effectors of microbial killing
DM Clancy, GP Sullivan, HBT Moran, CM Henry, EP Reeves, ...
Cell reports 22 (11), 2937-2950, 2018
1962018
Necroptosis suppresses inflammation via termination of TNF-or LPS-induced cytokine and chemokine production
CJ Kearney, SP Cullen, GA Tynan, CM Henry, D Clancy, EC Lavelle, ...
Cell Death & Differentiation 22 (8), 1313-1327, 2015
1592015
The receptor DNGR-1 signals for phagosomal rupture to promote cross-presentation of dead-cell-associated antigens
J Canton, H Blees, CM Henry, MD Buck, O Schulz, NC Rogers, E Childs, ...
Nature immunology 22 (2), 140-153, 2021
1502021
Neutrophil extracellular traps can serve as platforms for processing and activation of IL‐1 family cytokines
DM Clancy, CM Henry, GP Sullivan, SJ Martin
The FEBS journal 284 (11), 1712-1725, 2017
1282017
Distinguishing between apoptosis, necrosis, necroptosis and other cell death modalities.
SJ Martin, CM Henry
Methods (San Diego, Calif.) 61 (2), 87-89, 2013
682013
TRAIL receptors serve as stress-associated molecular patterns to promote ER-stress-induced inflammation
GP Sullivan, H O’Connor, CM Henry, P Davidovich, DM Clancy, ML Albert, ...
Developmental Cell 52 (6), 714-730. e5, 2020
642020
Suppressing IL-36-driven inflammation using peptide pseudosubstrates for neutrophil proteases
GP Sullivan, CM Henry, DM Clancy, T Mametnabiev, E Belotcerkovskaya, ...
Cell death & disease 9 (3), 378, 2018
502018
Identification of small‐molecule elastase inhibitors as antagonists of IL‐36 cytokine activation
GP Sullivan, PB Davidovich, S Sura‐Trueba, E Belotcerkovskaya, ...
FEBS open bio 8 (5), 751-763, 2018
212018
α-actinin accounts for the bioactivity of actin preparations in inducing STAT target genes in Drosophila melanogaster
O Gordon, CM Henry, N Srinivasan, S Ahrens, A Franz, S Deddouche, ...
Elife 7, e38636, 2018
192018
Production of biologically active IL‐36 family cytokines through insertion of N‐terminal caspase cleavage motifs
DM Clancy, CM Henry, PB Davidovich, GP Sullivan, E Belotcerkovskaya, ...
FEBS Open Bio 6 (4), 338-348, 2016
172016
DNGR-1-mediated cross-presentation of dead cell-associated antigens
CM Henry, CA Castellanos, CR e Sousa
Seminars in Immunology 66, 101726, 2023
152023
Maintenance and loss of endocytic organelle integrity: mechanisms and implications for antigen cross-presentation
E Childs, CM Henry, J Canton, C Reis e Sousa
Open Biology 11 (11), 210194, 2021
152021
Staying alive: defensive strategies in the BCL-2 family playbook
SP Cullen, CM Henry, SJ Martin
Molecular Cell 44 (4), 509-510, 2011
62011
SYK ubiquitination by CBL E3 ligases restrains cross-presentation of dead cell-associated antigens by type 1 dendritic cells
CM Henry, CA Castellanos, MD Buck, E Giampazolias, B Frederico, ...
Cell reports 42 (12), 2023
32023
Use of inhibitors of il-36 proteolytic processing for the treatment and/or reduction of inflammation
SJ Martin, C Henry, G Sullivan
22016
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