Insights into G protein structure, function, and regulation TM Cabrera-Vera, J Vanhauwe, TO Thomas, M Medkova, A Preininger, ... Endocrine reviews 24 (6), 765-781, 2003 | 1017 | 2003 |
AI in health: state of the art, challenges, and future directions F Wang, A Preininger Yearbook of medical informatics 28 (01), 016-026, 2019 | 359 | 2019 |
Mechanism of the receptor-catalyzed activation of heterotrimeric G proteins WM Oldham, N Van Eps, AM Preininger, WL Hubbell, HE Hamm Nature structural & molecular biology 13 (9), 772-777, 2006 | 242 | 2006 |
Interaction of a G protein with an activated receptor opens the interdomain interface in the alpha subunit N Van Eps, AM Preininger, N Alexander, AI Kaya, S Meier, J Meiler, ... Proceedings of the National Academy of Sciences 108 (23), 9420-9424, 2011 | 203 | 2011 |
G protein βγ directly regulates SNARE protein fusion machinery for secretory granule exocytosis T Blackmer, EC Larsen, C Bartleson, JA Kowalchyk, EJ Yoon, ... Nature neuroscience 8 (4), 421-425, 2005 | 203 | 2005 |
G protein signaling: insights from new structures AM Preininger, HE Hamm Science's STKE 2004 (218), re3-re3, 2004 | 119 | 2004 |
Conformational flexibility and structural dynamics in GPCR-mediated G protein activation: a perspective AM Preininger, J Meiler, HE Hamm Journal of molecular biology 425 (13), 2288-2298, 2013 | 118 | 2013 |
Biochemical analysis of phospholipase D HA Brown, LG Henage, AM Preininger, Y Xiang, JH Exton Methods in enzymology 434, 49-87, 2007 | 99 | 2007 |
Conformational Changes in the Amino-Terminal Helix of the G Protein αi1 Following Dissociation From Gβγ Subunit and Activation M Medkova, AM Preininger, NJ Yu, WL Hubbell, HE Hamm Biochemistry 41 (31), 9962-9972, 2002 | 94 | 2002 |
Energetic analysis of the rhodopsin–G-protein complex links the α5 helix to GDP release NS Alexander, AM Preininger, AI Kaya, RA Stein, HE Hamm, J Meiler Nature structural & molecular biology 21 (1), 56-63, 2014 | 89 | 2014 |
Mapping allosteric connections from the receptor to the nucleotide-binding pocket of heterotrimeric G proteins WM Oldham, N Van Eps, AM Preininger, WL Hubbell, HE Hamm Proceedings of the National Academy of Sciences 104 (19), 7927-7932, 2007 | 89 | 2007 |
Quantification of diacylglycerol species from cellular extracts by electrospray ionization mass spectrometry using a linear regression algorithm HL Callender, JS Forrester, P Ivanova, A Preininger, S Milne, HA Brown Analytical chemistry 79 (1), 263-272, 2007 | 59 | 2007 |
The Myristoylated Amino Terminus of Gαi1 Plays a Critical Role in the Structure and Function of Gαi1 Subunits in Solution AM Preininger, N Van Eps, NJ Yu, M Medkova, WL Hubbell, HE Hamm Biochemistry 42 (26), 7931-7941, 2003 | 59 | 2003 |
Direct modulation of phospholipase D activity by Gβγ AM Preininger, LG Henage, WM Oldham, EJ Yoon, HE Hamm, HA Brown Molecular pharmacology 70 (1), 311-318, 2006 | 47 | 2006 |
Irreversible platelet activation requires protease-activated receptor 1-mediated signaling to phosphatidylinositol phosphates M Holinstat, AM Preininger, SB Milne, WJ Hudson, HA Brown, HE Hamm Molecular pharmacology 76 (2), 301-313, 2009 | 46 | 2009 |
Gβγ directly modulates vesicle fusion by competing with synaptotagmin for binding to neuronal SNARE proteins embedded in membranes Z Zurawski, B Page, MC Chicka, RL Brindley, CA Wells, AM Preininger, ... Journal of Biological Chemistry 292 (29), 12165-12177, 2017 | 38 | 2017 |
Coupling efficiency of rhodopsin and transducin in bicelles AI Kaya, TM Thaker, AM Preininger, TM Iverson, HE Hamm Biochemistry 50 (15), 3193-3203, 2011 | 35 | 2011 |
Helix Dipole Movement and Conformational Variability Contribute to Allosteric GDP Release in Gαi Subunits, AM Preininger, MA Funk, WM Oldham, SM Meier, CA Johnston, ... Biochemistry 48 (12), 2630-2642, 2009 | 35 | 2009 |
Trp fluorescence reveals an activation‐dependent cation‐π interaction in the Switch II region of Gαi proteins HE Hamm, SM Meier, G Liao, AM Preininger Protein Science 18 (11), 2326-2335, 2009 | 28 | 2009 |
Myristoylation exerts direct and allosteric effects on Gα conformation and dynamics in solution AM Preininger, AI Kaya, JA Gilbert III, LS Busenlehner, RN Armstrong, ... Biochemistry 51 (9), 1911-1924, 2012 | 24 | 2012 |