Thermal conductivity of carbon nanotubes J Che, T Cagin, WA Goddard III Nanotechnology 11 (2), 65, 2000 | 1538 | 2000 |
Meta-and orthogonal integration of influenza “OMICs” data defines a role for UBR4 in virus budding S Tripathi, MO Pohl, Y Zhou, A Rodriguez-Frandsen, G Wang, DA Stein, ... Cell host & microbe 18 (6), 723-735, 2015 | 941 | 2015 |
Targeting Wnt-driven cancer through the inhibition of Porcupine by LGK974 J Liu, S Pan, MH Hsieh, N Ng, F Sun, T Wang, S Kasibhatla, AG Schuller, ... Proceedings of the National Academy of Sciences 110 (50), 20224-20229, 2013 | 882 | 2013 |
Quantum control of wave packet evolution with tailored femtosecond pulses B Kohler, VV Yakovlev, J Che, JL Krause, M Messina, KR Wilson, ... Physical Review Letters 74 (17), 3360, 1995 | 462 | 1995 |
Thermal conductivity of diamond and related materials from molecular dynamics simulations J Che, T Çağın, W Deng, WA Goddard III The Journal of Chemical Physics 113 (16), 6888-6900, 2000 | 459 | 2000 |
Imaging of Plasmodium liver stages to drive next-generation antimalarial drug discovery S Meister, DM Plouffe, KL Kuhen, GMC Bonamy, T Wu, SW Barnes, ... Science 334 (6061), 1372-1377, 2011 | 388 | 2011 |
Mapping the degradable kinome provides a resource for expedited degrader development KA Donovan, FM Ferguson, JW Bushman, NA Eleuteri, D Bhunia, SS Ryu, ... Cell 183 (6), 1714-1731. e10, 2020 | 234 | 2020 |
Discovery of BAF312 (Siponimod), a potent and selective S1P receptor modulator S Pan, NS Gray, W Gao, Y Mi, Y Fan, X Wang, T Tuntland, J Che, ... ACS medicinal chemistry letters 4 (3), 333-337, 2013 | 190 | 2013 |
Quantum control of in the gas phase and in condensed phase solid Kr matrix CJ Bardeen, J Che, KR Wilson, VV Yakovlev, VA Apkarian, CC Martens, ... The Journal of chemical physics 106 (20), 8486-8503, 1997 | 177 | 1997 |
Molecular mechanisms of acquired resistance to MET tyrosine kinase inhibitors in patients with MET exon 14–mutant NSCLC G Recondo, M Bahcall, LF Spurr, J Che, B Ricciuti, GC Leonardi, YC Lo, ... Clinical Cancer Research 26 (11), 2615-2625, 2020 | 176 | 2020 |
Targeting MET Dysregulation in Cancer G Recondo, J Che, PA Jänne, MM Awad Cancer discovery 10 (7), 922-934, 2020 | 164 | 2020 |
Electrostatic free energy and its variations in implicit solvent models J Che, J Dzubiella, B Li, JA McCammon The Journal of Physical Chemistry B 112 (10), 3058-3069, 2008 | 125 | 2008 |
Quantum control of NaI photodissociation reaction product states by ultrafast tailored light pulses CJ Bardeen, J Che, KR Wilson, VV Yakovlev, P Cong, B Kohler, ... The Journal of Physical Chemistry A 101 (20), 3815-3822, 1997 | 124 | 1997 |
Lactate regulates cell cycle by remodelling the anaphase promoting complex W Liu, Y Wang, LHM Bozi, PD Fischer, MP Jedrychowski, H Xiao, T Wu, ... Nature 616 (7958), 790-797, 2023 | 120 | 2023 |
Fragment-based covalent ligand discovery W Lu, M Kostic, T Zhang, J Che, MP Patricelli, LH Jones, ET Chouchani, ... RSC chemical biology 2 (2), 354-367, 2021 | 110 | 2021 |
Discovery and resistance mechanism of a selective CDK12 degrader B Jiang, Y Gao, J Che, W Lu, IH Kaltheuner, R Dries, M Kalocsay, ... Nature chemical biology 17 (6), 675-683, 2021 | 102 | 2021 |
Design and synthesis of 7H-pyrrolo [2, 3-d] pyrimidines as focal adhesion kinase inhibitors. Part 2 HS Choi, Z Wang, W Richmond, X He, K Yang, T Jiang, D Karanewsky, ... Bioorganic & medicinal chemistry letters 16 (10), 2689-2692, 2006 | 83 | 2006 |
Pharmacological blockade of TEAD–YAP reveals its therapeutic limitation in cancer cells Y Sun, L Hu, Z Tao, GK Jarugumilli, H Erb, A Singh, Q Li, JL Cotton, ... Nature Communications 13 (1), 6744, 2022 | 78 | 2022 |
Expanding the diversity of allosteric bcr-abl inhibitors X Deng, B Okram, Q Ding, J Zhang, Y Choi, FJ Adrián, A Wojciechowski, ... Journal of medicinal chemistry 53 (19), 6934-6946, 2010 | 77 | 2010 |
Selective degradation of GSPT1 by cereblon modulators identified via a focused combinatorial library CE Powell, G Du, J Che, Z He, KA Donovan, H Yue, ES Wang, RP Nowak, ... ACS chemical biology 15 (10), 2722-2730, 2020 | 70 | 2020 |