| A single N-terminal cysteine in TRPV1 determines activation by pungent compounds from onion and garlic H Salazar, I Llorente, A Jara-Oseguera, R García-Villegas, M Munari, ... Nature neuroscience 11 (3), 255-261, 2008 | 245 | 2008 |
| Lysophosphatidic acid directly activates TRPV1 through a C-terminal binding site A Nieto-Posadas, G Picazo-Juárez, I Llorente, A Jara-Oseguera, ... Nature chemical biology 8 (1), 78-85, 2012 | 232 | 2012 |
| Voltage Sensitivity and Gating Charge in Shaker and Shab Family Potassium Channels LD Islas, FJ Sigworth The Journal of general physiology 114 (5), 723-742, 1999 | 201 | 1999 |
| Identification of a binding motif in the S5 helix that confers cholesterol sensitivity to the TRPV1 ion channel G Picazo-Juárez, S Romero-Suárez, A Nieto-Posadas, I Llorente, ... Journal of Biological Chemistry 286 (28), 24966-24976, 2011 | 156 | 2011 |
| Electrostatics and the gating pore of Shaker potassium channels LD Islas, FJ Sigworth The Journal of general physiology 117 (1), 69, 2001 | 146 | 2001 |
| Structural determinants of gating in the TRPV1 channel H Salazar, A Jara-Oseguera, E Hernandez-Garcia, I Llorente, ... Nature structural & molecular biology 16 (7), 704-710, 2009 | 124 | 2009 |
| pH-dependent modulation of the cloned renal K+ channel, ROMK CM McNicholas, GG MacGregor, LD Islas, Y Yang, SC Hebert, G Giebisch American Journal of Physiology-Renal Physiology 275 (6), F972-F981, 1998 | 117 | 1998 |
| Structure and rearrangements in the carboxy-terminal region of SpIH channels GE Flynn, KD Black, LD Islas, B Sankaran, WN Zagotta Structure 15 (6), 671-682, 2007 | 109 | 2007 |
| TRPV1 channels and the progesterone receptor Sig-1R interact to regulate pain M Ortíz-Rentería, R Juárez-Contreras, R González-Ramírez, LD Islas, ... Proceedings of the National Academy of Sciences 115 (7), E1657-E1666, 2018 | 86 | 2018 |
| The role of allosteric coupling on thermal activation of thermo-TRP channels A Jara-Oseguera, LD Islas Biophysical journal 104 (10), 2160-2169, 2013 | 79 | 2013 |
| Two-microelectrode voltage clamp of Xenopus oocytes: voltage errors and compensation for local current flow W Baumgartner, L Islas, FJ Sigworth Biophysical journal 77 (4), 1980-1991, 1999 | 73 | 1999 |
| Inhibition of TRPV1 channels by a naturally occurring omega-9 fatty acid reduces pain and itch SL Morales-Lázaro, I Llorente, F Sierra-Ramírez, AE López-Romero, ... Nature communications 7 (1), 13092, 2016 | 71 | 2016 |
| TRP channels: a journey towards a molecular understanding of pain T Rosenbaum, SL Morales-Lázaro, LD Islas Nature Reviews Neuroscience 23 (10), 596-610, 2022 | 61 | 2022 |
| Irreversible temperature gating in trpv1 sheds light on channel activation A Sánchez-Moreno, E Guevara-Hernández, R Contreras-Cervera, ... Elife 7, e36372, 2018 | 55 | 2018 |
| Short-range molecular rearrangements in ion channels detected by tryptophan quenching of bimane fluorescence LD Islas, WN Zagotta The Journal of General Physiology 128 (3), 337-346, 2006 | 55 | 2006 |
| Voltage-dependent gating and gating charge measurements in the Kv1. 2 potassium channel IG Ishida, GE Rangel-Yescas, J Carrasco-Zanini, LD Islas Journal of General Physiology 145 (4), 345-358, 2015 | 50 | 2015 |
| On the mechanism of TBA block of the TRPV1 channel AJ Oseguera, LD Islas, R García-Villegas, T Rosenbaum Biophysical Journal 92 (11), 3901-3914, 2007 | 50 | 2007 |
| Properties of the inner pore region of TRPV1 channels revealed by block with quaternary ammoniums A Jara-Oseguera, I Llorente, T Rosenbaum, LD Islas The Journal of general physiology 132 (5), 547-562, 2008 | 49 | 2008 |
| Molecular physiology of TRPV channels: controversies and future challenges T Rosenbaum, LD Islas Annual Review of Physiology 85 (1), 293-316, 2023 | 44 | 2023 |
| Single molecule fluorescence studies of surface-adsorbed fibronectin M Antia, LD Islas, DA Boness, G Baneyx, V Vogel Biomaterials 27 (5), 679-690, 2006 | 42 | 2006 |
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