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Grégory Upert
Grégory Upert
Bright Peak Therapeutics
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Chimeric peptidomimetic antibiotics against Gram-negative bacteria
A Luther, M Urfer, M Zahn, M Müller, SY Wang, M Mondal, A Vitale, ...
Nature 576 (7787), 452-458, 2019
2942019
Enamine catalysis with low catalyst loadings-high efficiency via kinetic studies
M Wiesner, G Upert, G Angelici, H Wennemers
Journal of the American Chemical Society 132 (1), 6-7, 2010
2152010
Peptidomic comparison and characterization of the major components of the venom of the giant ant Dinoponera quadriceps collected in four different areas of Brazil
CT Cologna, J dos Santos Cardoso, E Jourdan, M Degueldre, G Upert, ...
Journal of proteomics 94, 413-422, 2013
742013
Emerging peptide antibiotics with therapeutic potential
G Upert, A Luther, D Obrecht, P Ermert
Medicine in drug discovery 9, 100078, 2021
732021
Oligoprolines as scaffolds for the formation of silver nanoparticles in defined sizes: correlating molecular and nanoscopic dimensions
G Upert, F Bouillère, H Wennemers
Angewandte Chemie International Edition 51 (17), 4231-4234, 2012
692012
Silver nanoparticle formation in different sizes induced by peptides identified within split‐and‐mix libraries
K Belser, T Vig Slenters, C Pfumbidzai, G Upert, L Mirolo, KM Fromm, ...
Angewandte Chemie International Edition 48 (20), 3661-3664, 2009
682009
Antibiotic polymyxin arranges lipopolysaccharide into crystalline structures to solidify the bacterial membrane
S Manioglu, SM Modaresi, N Ritzmann, J Thoma, SA Overall, A Harms, ...
Nature communications 13 (1), 6195, 2022
662022
RgIA4 potently blocks mouse α9α10 nAChRs and provides long lasting protection against oxaliplatin-induced cold allodynia
SB Christensen, AJ Hone, I Roux, J Kniazeff, JP Pin, G Upert, D Servent, ...
Frontiers in cellular neuroscience 11, 219, 2017
662017
Identification, structural and pharmacological characterization of τ-CnVA, a conopeptide that selectively interacts with somatostatin sst3 receptor
C Petrel, HG Hocking, M Reynaud, G Upert, P Favreau, D Biass, ...
Biochemical pharmacology 85 (11), 1663-1671, 2013
502013
Zinc-selective inhibition of the promiscuous bacterial amide-hydrolase DapE: implications of metal heterogeneity for evolution and antibiotic drug design
NR Uda, G Upert, G Angelici, S Nicolet, T Schmidt, T Schwede, M Creus
Metallomics 6 (1), 88-95, 2014
302014
An efficient biodelivery system for antisense polyamide nucleic acid (PNA)
M Mehiri, G Upert, S Tripathi, A Di Giorgio, R Condom, VN Pandey, ...
Oligonucleotides 18 (3), 245-256, 2008
242008
New α-adrenergic property for synthetic MTβ and CM-3 three-finger fold toxins from black mamba
G Blanchet, G Upert, G Mourier, B Gilquin, N Gilles, D Servent
Toxicon 75, 160-167, 2013
232013
Ancestral protein resurrection and engineering opportunities of the mamba aminergic toxins
G Blanchet, D Alili, A Protte, G Upert, N Gilles, L Tepshi, EA Stura, ...
Scientific Reports 7 (1), 2701, 2017
222017
Combined use of ion mobility and collision-induced dissociation to investigate the opening of disulfide bridges by electron-transfer dissociation in peptides bearing two …
P Massonnet, G Upert, N Smargiasso, N Gilles, L Quinton, E De Pauw
Analytical Chemistry 87 (10), 5240-5246, 2015
222015
Peptidomimetic antibiotics disrupt the lipopolysaccharide transport bridge of drug-resistant Enterobacteriaceae
M Schuster, E Brabet, KK Oi, N Desjonquères, K Moehle, K Le Poupon, ...
Science Advances 9 (21), eadg3683, 2023
212023
A venomics approach coupled to high-throughput toxin production strategies identifies the first venom-derived melanocortin receptor agonists
S Reynaud, J Ciolek, M Degueldre, NJ Saez, AF Sequeira, Y Duhoo, ...
Journal of medicinal chemistry 63 (15), 8250-8264, 2020
202020
Ion mobility-mass spectrometry as a tool for the structural characterization of peptides bearing intramolecular disulfide bond (s)
P Massonnet, JRN Haler, G Upert, M Degueldre, D Morsa, N Smargiasso, ...
Journal of The American Society for Mass Spectrometry 27 (10), 1637-1646, 2016
182016
Thieme chemistry journals awardees–where are they now? A stereoselective tripeptide catalyst for conjugate addition reactions of acetophenones to dicyanoolefins
T Schnitzer, H Wennemers
Synlett 28 (11), 1282-1286, 2017
172017
A new Kunitz‐type snake toxin family associated with an original mode of interaction with the vasopressin 2 receptor
L Droctové, J Ciolek, C Mendre, A Chorfa, P Huerta, C Carvalho, C Gouin, ...
British journal of pharmacology 179 (13), 3470-3481, 2022
152022
Effect of γ-substituted proline derivatives on the performance of the peptidic catalyst H-dPro-pro-Glu-NH2
T Schnitzer, H Wennemers
Synthesis 50 (22), 4377-4382, 2018
152018
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학술자료 1–20