Multiomics Profiling Establishes the Polypharmacology of FDA-Approved CDK4/6 Inhibitors and the Potential for Differential Clinical Activity M Hafner, CE Mills, K Subramanian, C Chen, M Chung, SA Boswell, ... Cell chemical biology, 2019 | 225* | 2019 |
From word models to executable models of signaling networks using automated assembly BM Gyori, JA Bachman, K Subramanian, JL Muhlich, L Galescu, ... Molecular systems biology 13 (11), 954, 2017 | 180 | 2017 |
A Multi-center Study on the Reproducibility of Drug-Response Assays in Mammalian Cell Lines M Niepel, M Hafner, CE Mills, K Subramanian, EH Williams, M Chung, ... Cell Systems, 2019 | 138 | 2019 |
A dynamic view of the proteomic landscape during differentiation of ReNcell VM cells, an immortalized human neural progenitor line Y Song, K Subramanian, MJ Berberich, S Rodriguez, IJ Latorre, CM Luria, ... Scientific data 6 (1), 1-17, 2019 | 46 | 2019 |
Time resolved phosphoproteomics reveals scaffolding and catalysis-responsive patterns of SHP2-dependent signaling V Vemulapalli, LA Chylek, A Erickson, A Pfeiffer, KH Gabriel, ... eLife 10, e64251, 2021 | 36* | 2021 |
Inhibition of Haspin Kinase Promotes Cell-Intrinsic and Extrinsic Antitumor Activity JC Melms, S Vallabhaneni, CE Mills, C Yapp, JY Chen, E Morelli, ... Cancer Research 80 (4), 798-810, 2020 | 31 | 2020 |
Designing Drug‐Response Experiments and Quantifying their Results M Hafner, M Niepel, K Subramanian, PK Sorger Current protocols in chemical biology 9 (2), 96-116, 2018 | 30 | 2018 |
Community Assessment of the Predictability of Cancer Protein and Phosphoprotein Levels from Genomics and Transcriptomics M Yang, F Petralia, Z Li, H Li, W Ma, X Song, S Kim, H Lee, H Yu, B Lee, ... Cell Systems 11 (2), 186-195. e9, 2020 | 28 | 2020 |
A multi-omic analysis of MCF10A cells provides a resource for integrative assessment of ligand-mediated molecular and phenotypic responses SM Gross, MA Dane, RL Smith, KL Devlin, IC McLean, DS Derrick, ... Communications biology 5 (1), 1-20, 2022 | 26* | 2022 |
Potential role of a bistable histidine kinase switch in the asymmetric division cycle of Caulobacter crescentus K Subramanian, MR Paul, JJ Tyson PLoS computational biology 9 (9), e1003221, 2013 | 25 | 2013 |
Chemical Biology Toolkit for DCLK1 Reveals Connection to RNA Processing Y Liu, FM Ferguson, L Li, M Kuljanin, CE Mills, K Subramanian, ... Cell Chemical Biology 27 (10), 1229-1240. e4, 2020 | 23 | 2020 |
Multiplexed and reproducible high content screening of live and fixed cells using Dye Drop CE Mills, K Subramanian, M Hafner, M Niepel, L Gerosa, M Chung, ... Nature Communications 13 (1), 1-18, 2022 | 22* | 2022 |
Dynamical localization of DivL and PleC in the asymmetric Division cycle of Caulobacter crescentus: a theoretical investigation of alternative models K Subramanian, MR Paul, JJ Tyson PLoS computational biology 11 (7), e1004348, 2015 | 22 | 2015 |
A multitargeted probe-based strategy to identify signaling vulnerabilities in cancers S Rao, G Du, M Hafner, K Subramanian, PK Sorger, NS Gray Journal of Biological Chemistry 294 (21), 8664-8673, 2019 | 16 | 2019 |
A stochastic spatiotemporal model of a response-regulator network in the Caulobacter crescentus cell cycle F Li, K Subramanian, M Chen, JJ Tyson, Y Cao Physical biology 13 (3), 035007, 2016 | 13 | 2016 |
Two-dimensional model of bipolar PopZ polymerization in caulobacter crescentus M Chen, F Li, K Subramanian, J Tyson, Y Cao Proceedings of the 6th ACM Conference on Bioinformatics, Computational …, 2015 | 8 | 2015 |
Spatiotemporal Models of the Asymmetric Division Cycle of Caulobacter crescentus K Subramanian, JJ Tyson Asymmetric Cell Division in Development, Differentiation and Cancer, 23-48, 2017 | 7 | 2017 |
Robustness of the Drosophila segment polarity network to transient perturbations K Subramanian, C Gadgil IET systems biology 4 (2), 169-176, 2010 | 7 | 2010 |
Proteomic profiling across breast cancer cell lines and models M Kalocsay, MJ Berberich, RA Everley, MK Nariya, M Chung, B Gaudio, ... Scientific Data 10 (1), 514, 2023 | 6 | 2023 |
De novo production of Turing activator generates polarity in pattern formation K Subramanian, MR Paul, JJ Tyson advances in Systems and Synthetic Biology, 2014 | 4 | 2014 |