Apoptosis induction in human breast cancer (MCF-7) cells by a novel venom l-amino acid oxidase (Rusvinoxidase) is independent of its enzymatic activity and is … AK Mukherjee, AJ Saviola, PD Burns, SP Mackessy Apoptosis 20, 1358-1372, 2015 | 102 | 2015 |
Comparative venomics of the Prairie Rattlesnake (Crotalus viridis viridis) from Colorado: Identification of a novel pattern of ontogenetic changes in venom composition and … AJ Saviola, D Pla, L Sanz, TA Castoe, JJ Calvete, SP Mackessy Journal of proteomics 121, 28-43, 2015 | 98 | 2015 |
Impact of the Identification Strategy on the Reproducibility of the DDA and DIA Results C Fernández-Costa, S Martínez-Bartolomé, DB McClatchy, AJ Saviola, ... Journal of proteome research 19 (8), 3153-3161, 2020 | 96 | 2020 |
Understanding biological roles of venoms among the Caenophidia: The importance of rear-fanged snakes SP Mackessy, AJ Saviola Integrative and Comparative Biology 56 (5), 1004-1021, 2016 | 72 | 2016 |
Transcriptomics-guided bottom-up and top-down venomics of neonate and adult specimens of the arboreal rear-fanged Brown Treesnake, Boiga irregularis, from Guam D Pla, D Petras, AJ Saviola, CM Modahl, L Sanz, A Pérez, E Juárez, ... Journal of proteomics 174, 71-84, 2018 | 71 | 2018 |
Molecular basis for prey relocation in viperid snakes AJ Saviola, D Chiszar, C Busch, SP Mackessy Bmc Biology 11, 1-10, 2013 | 69 | 2013 |
Rear-fanged snake venoms: an untapped source of novel compounds and potential drug leads AJ Saviola, ME Peichoto, SP Mackessy Toxin Reviews 33 (4), 185-201, 2014 | 63 | 2014 |
The disintegrin tzabcanin inhibits adhesion and migration in melanoma and lung cancer cells AJ Saviola, PD Burns, AK Mukherjee, SP Mackessy International journal of biological macromolecules 88, 457-464, 2016 | 57 | 2016 |
Venom Ontogeny in the Mexican Lance-Headed Rattlesnake (Crotalus polystictus) SP Mackessy, J Leroy, E Mociño-Deloya, K Setser, RW Bryson, ... Toxins 10 (7), 271, 2018 | 53 | 2018 |
Simultaneous targeting of PD-1 and IL-2Rβγ with radiation therapy inhibits pancreatic cancer growth and metastasis M Piper, M Hoen, LB Darragh, MW Knitz, D Nguyen, J Gadwa, G Durini, ... Cancer Cell 41 (5), 950-969. e6, 2023 | 42 | 2023 |
Mutual enlightenment: A toolbox of concepts and methods for integrating evolutionary and clinical toxinology via snake venomics and the contextual stance JJ Calvete, B Lomonte, AJ Saviola, F Bonilla, M Sasa, DJ Williams, ... Toxicon: X 9, 100070, 2021 | 40 | 2021 |
EThcD and 213 nm UVPD for top-down analysis of bovine seminal plasma proteoforms on electrophoretic and chromatographic time frames FP Gomes, JK Diedrich, AJ Saviola, E Memili, AA Moura, JR Yates III Analytical chemistry 92 (4), 2979-2987, 2020 | 37 | 2020 |
Mass spectrometry-based atlas of extracellular matrix proteins across 25 mouse organs MC McCabe, AJ Saviola, KC Hansen Journal of proteome research 22 (3), 790-801, 2023 | 36 | 2023 |
Evaluation of cytotoxic activities of snake venoms toward breast (MCF-7) and skin cancer (A-375) cell lines MJ Bradshaw, AJ Saviola, E Fesler, SP Mackessy Cytotechnology 68, 687-700, 2016 | 36 | 2016 |
Disintegrins of Crotalus simus tzabcan venom: Isolation, characterization and evaluation of the cytotoxic and anti-adhesion activities of tzabcanin, a new RGD disintegrin AJ Saviola, CM Modahl, SP Mackessy Biochimie 116, 92-102, 2015 | 35 | 2015 |
The emerging field of venom-microbiomics for exploring venom as a microenvironment, and the corresponding Initiative for Venom Associated Microbes and Parasites (iVAMP) S Ul-Hasan, E Rodríguez-Román, AM Reitzel, RMM Adams, V Herzig, ... Toxicon: X 4, 100016, 2019 | 34 | 2019 |
Venom phenotypes of the Rock Rattlesnake (Crotalus lepidus) and the Ridge-nosed Rattlesnake (Crotalus willardi) from México and the United States AJ Saviola, AJ Gandara, RW Bryson Jr, SP Mackessy Toxicon 138, 119-129, 2017 | 34 | 2017 |
Venom Composition in a Phenotypically Variable Pit Viper (Trimeresurus insularis) across the Lesser Sunda Archipelago BK Jones, AJ Saviola, SB Reilly, AL Stubbs, E Arida, DT Iskandar, ... Journal of proteome research 18 (5), 2206-2220, 2019 | 29 | 2019 |
Snakes on a plain: biotic and abiotic factors determine venom compositional variation in a wide-ranging generalist rattlesnake CF Smith, ZL Nikolakis, K Ivey, BW Perry, DR Schield, NR Balchan, ... BMC biology 21 (1), 136, 2023 | 27 | 2023 |
Phenotypic and functional variation in venom and venom resistance of two sympatric rattlesnakes and their prey KE Robinson, ML Holding, MD Whitford, AJ Saviola, JR Yates III, ... Journal of Evolutionary Biology, 2021 | 26 | 2021 |