Inhibition of JNK phosphorylation by a novel curcumin analog prevents high glucose–induced inflammation and apoptosis in cardiomyocytes and the development of diabetic … Y Pan, Y Wang, Y Zhao, K Peng, W Li, Y Wang, J Zhang, S Zhou, Q Liu, ... Diabetes 63 (10), 3497-3511, 2014 | 215 | 2014 |
The role of sphingosine 1‐phosphate receptor 2 in bile‐acid–induced cholangiocyte proliferation and cholestasis‐induced liver injury in mice Y Wang, H Aoki, J Yang, K Peng, R Liu, X Li, X Qiang, L Sun, EC Gurley, ... Hepatology 65 (6), 2005-2018, 2017 | 205 | 2017 |
Conjugated bile acid–activated S1P receptor 2 is a key regulator of sphingosine kinase 2 and hepatic gene expression M Nagahashi, K Takabe, R Liu, K Peng, X Wang, Y Wang, NC Hait, ... Hepatology 61 (4), 1216-1226, 2015 | 197 | 2015 |
Histone demethylase JMJD1A promotes urinary bladder cancer progression by enhancing glycolysis through coactivation of hypoxia inducible factor 1α W Wan, K Peng, M Li, L Qin, Z Tong, J Yan, B Shen, C Yu Oncogene 36 (27), 3868-3877, 2017 | 100 | 2017 |
Histone demethylase JMJD2D interacts with β-catenin to induce transcription and activate colorectal cancer cell proliferation and tumor growth in mice K Peng, L Kou, L Yu, C Bai, M Li, P Mo, W Li, C Yu Gastroenterology 156 (4), 1112-1126, 2019 | 93 | 2019 |
Novel EGFR inhibitors attenuate cardiac hypertrophy induced by angiotensin II K Peng, X Tian, Y Qian, M Skibba, C Zou, Z Liu, J Wang, Z Xu, X Li, ... Journal of cellular and molecular medicine 20 (3), 482-494, 2016 | 73 | 2016 |
Inhibition of MAPK‐mediated ACE expression by compound C66 prevents STZ‐induced diabetic nephropathy Y Pan, Y Huang, Z Wang, Q Fang, Y Sun, C Tong, K Peng, Y Wang, ... Journal of Cellular and Molecular Medicine 18 (2), 231-241, 2014 | 66 | 2014 |
Histone demethylase JMJD1A promotes colorectal cancer growth and metastasis by enhancing Wnt/β-catenin signaling K Peng, G Su, J Ji, X Yang, M Miao, P Mo, M Li, J Xu, W Li, C Yu Journal of Biological Chemistry 293 (27), 10606-10619, 2018 | 59 | 2018 |
Histone acetyl transferase GCN5 promotes human hepatocellular carcinoma progression by enhancing AIB1 expression S Majaz, Z Tong, K Peng, W Wang, W Ren, M Li, K Liu, P Mo, W Li, C Yu Cell & bioscience 6, 1-11, 2016 | 51 | 2016 |
11β-Hydroxysteroid Dehydrogenase Type 1 (11β-HSD1) mediates insulin resistance through JNK activation in adipocytes K Peng, Y Pan, J Li, Z Khan, M Fan, H Yin, C Tong, Y Zhao, G Liang, ... Scientific reports 6 (1), 37160, 2016 | 43 | 2016 |
Novel epidermal growth factor receptor inhibitor attenuates angiotensin II–induced kidney fibrosis Y Qian, K Peng, C Qiu, M Skibba, Y Huang, Z Xu, Y Zhang, J Hu, D Liang, ... Journal of Pharmacology and Experimental Therapeutics 356 (1), 32-42, 2016 | 36 | 2016 |
Discovery and evaluation of novel anti-inflammatory derivatives of natural bioactive curcumin Y Zhang, X Jiang, K Peng, C Chen, L Fu, Z Wang, J Feng, Z Liu, H Zhang, ... Drug design, development and therapy, 2161-2171, 2014 | 35 | 2014 |
Histone demethylase JMJD2D activates HIF1 signaling pathway via multiple mechanisms to promote colorectal cancer glycolysis and progression K Peng, M Zhuo, M Li, Q Chen, P Mo, C Yu Oncogene 39 (47), 7076-7091, 2020 | 34 | 2020 |
An oxygen-chelate complex, palladium bis-acetylacetonate, induces apoptosis in H460 cells via endoplasmic reticulum stress pathway rather than interacting with DNA Y Wang, J Hu, Y Cai, S Xu, B Weng, K Peng, X Wei, T Wei, H Zhou, X Li, ... Journal of Medicinal Chemistry 56 (23), 9601-9611, 2013 | 32 | 2013 |
Inflammation-induced JMJD2D promotes colitis recovery and colon tumorigenesis by activating Hedgehog signaling M Zhuo, W Chen, S Shang, P Guo, K Peng, M Li, P Mo, Y Zhang, X Qiu, ... Oncogene 39 (16), 3336-3353, 2020 | 31 | 2020 |
Inhibition of inflammation and oxidative stress by an imidazopyridine derivative X22 prevents heart injury from obesity Y Qian, Y Zhang, P Zhong, K Peng, Z Xu, X Chen, K Lu, G Chen, X Li, ... Journal of Cellular and Molecular Medicine 20 (8), 1427-1442, 2016 | 31 | 2016 |
HIV protease inhibitors in gut barrier dysfunction and liver injury X Wu, Y Li, K Peng, H Zhou Current opinion in pharmacology 19, 61-66, 2014 | 24 | 2014 |
New EGFR inhibitor, 453, prevents renal fibrosis in angiotensin II-stimulated mice M Skibba, Y Qian, Y Bao, J Lan, K Peng, Y Zhao, P Zhong, J Hu, X Li, ... European Journal of Pharmacology 789, 421-430, 2016 | 23 | 2016 |
Demethylase JMJD2D induces PD-L1 expression to promote colorectal cancer immune escape by enhancing IFNGR1-STAT3-IRF1 signaling Q Chen, S Zhuang, Y Hong, L Yang, P Guo, P Mo, K Peng, W Li, N Xiao, ... Oncogene 41 (10), 1421-1433, 2022 | 22 | 2022 |
Inhibition of 11b-HSD1 by LG13 improves glucose metabolism in type 2 diabetic mice L Zhao, Y Pan, K Peng, Z Wang, J Li, D Li, C Tong, Y Wang, G Liang J. Mol. Endocrinol 55, 119-131, 2015 | 14 | 2015 |