DNA secondary structures: stability and function of G-quadruplex structures ML Bochman, K Paeschke, VA Zakian Nature Reviews Genetics 13 (11), 770-780, 2012 | 1698 | 2012 |
Telomere end-binding proteins control the formation of G-quadruplex DNA structures in vivo K Paeschke, T Simonsson, J Postberg, D Rhodes, HJ Lipps Nature structural & molecular biology 12 (10), 847-854, 2005 | 711 | 2005 |
DNA replication through G-quadruplex motifs is promoted by the Saccharomyces cerevisiae Pif1 DNA helicase K Paeschke, JA Capra, VA Zakian Cell 145 (5), 678-691, 2011 | 627 | 2011 |
Pif1 family helicases suppress genome instability at G-quadruplex motifs K Paeschke, ML Bochman, PD Garcia, P Cejka, KL Friedman, ... Nature 497 (7450), 458-462, 2013 | 526 | 2013 |
G-quadruplexes: a promising target for cancer therapy N Kosiol, S Juranek, P Brossart, A Heine, K Paeschke Molecular Cancer 20, 1-18, 2021 | 396 | 2021 |
G-Quadruplex DNA Sequences Are Evolutionarily Conserved and Associated with Distinct Genomic Features in Saccharomyces cerevisiae JA Capra, K Paeschke, M Singh, VA Zakian PLoS computational biology 6 (7), e1000861, 2010 | 328 | 2010 |
Telomerase recruitment by the telomere end binding protein-β facilitates G-quadruplex DNA unfolding in ciliates K Paeschke, S Juranek, T Simonsson, A Hempel, D Rhodes, HJ Lipps Nature structural & molecular biology 15 (6), 598-604, 2008 | 191 | 2008 |
G-quadruplex unwinding helicases and their function in vivo M Sauer, K Paeschke Biochemical Society Transactions 45 (5), 1173-1182, 2017 | 175 | 2017 |
DHX36 prevents the accumulation of translationally inactive mRNAs with G4-structures in untranslated regions M Sauer, SA Juranek, J Marks, A De Magis, HG Kazemier, D Hilbig, ... Nature communications 10 (1), 2421, 2019 | 144 | 2019 |
The human CCHC-type zinc finger nucleic acid-binding protein binds G-rich elements in target mRNA coding sequences and promotes translation D Benhalevy, SK Gupta, CH Danan, S Ghosal, HW Sun, HG Kazemier, ... Cell reports 18 (12), 2979-2990, 2017 | 138 | 2017 |
Telomeres: structures in need of unwinding K Paeschke, KR McDonald, VA Zakian FEBS letters 584 (17), 3760-3772, 2010 | 120 | 2010 |
Reduced Rif2 and lack of Mec1 target short telomeres for elongation rather than double-strand break repair JS McGee, JA Phillips, A Chan, M Sabourin, K Paeschke, VA Zakian Nature structural & molecular biology 17 (12), 1438-1445, 2010 | 101 | 2010 |
Impaired neurogenesis alters brain biomechanics in a neuroprogenitor-based genetic subtype of congenital hydrocephalus PQ Duy, SC Weise, C Marini, XJ Li, D Liang, PJ Dahl, S Ma, A Spajic, ... Nature neuroscience 25 (4), 458-473, 2022 | 72 | 2022 |
The pif1 helicase, a negative regulator of telomerase, acts preferentially at long telomeres JA Phillips, A Chan, K Paeschke, VA Zakian PLoS genetics 11 (4), e1005186, 2015 | 55 | 2015 |
The relevance of G-quadruplexes for DNA repair R Linke, M Limmer, SA Juranek, A Heine, K Paeschke International Journal of Molecular Sciences 22 (22), 12599, 2021 | 53 | 2021 |
Hrq1, a homolog of the human RecQ4 helicase, acts catalytically and structurally to promote genome integrity ML Bochman, K Paeschke, A Chan, VA Zakian Cell reports 6 (2), 346-356, 2014 | 53 | 2014 |
Guanine quadruplex monoclonal antibody 1H6 cross-reacts with restrained thymidine-rich single stranded DNA HG Kazemier, K Paeschke, PM Lansdorp Nucleic acids research 45 (10), 5913-5919, 2017 | 44 | 2017 |
The use of RNAi to analyze gene function in spirotrichous ciliates AG Paschka, F Jönsson, V Maier, M Möllenbeck, K Paeschke, J Postberg, ... European journal of protistology 39 (4), 449-454, 2003 | 38 | 2003 |
Zuo1 supports G4 structure formation and directs repair toward nucleotide excision repair A De Magis, S Götz, M Hajikazemi, E Fekete-Szücs, M Caterino, ... Nature communications 11 (1), 3907, 2020 | 37 | 2020 |
Probing telomeric G-quadruplex DNA structures in cells with in vitro generated single-chain antibody fragments C Schaffitzel, J Postberg, K Paeschke, HJ Lipps G-Quadruplex DNA: Methods and Protocols, 159-181, 2010 | 37 | 2010 |