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Alicia M Purkey
Alicia M Purkey
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Chemico-genetic discovery of astrocytic control of inhibition in vivo
T Takano, JT Wallace, KT Baldwin, AM Purkey, A Uezu, JL Courtland, ...
Nature 588 (7837), 296-302, 2020
1882020
Phosphorylation-Dependent Regulation of Ca2+-Permeable AMPA Receptors During Hippocampal Synaptic Plasticity
AM Purkey, ML Dell’Acqua
Frontiers in synaptic neuroscience 12, 8, 2020
1022020
AKAP150 palmitoylation regulates synaptic incorporation of Ca2+-permeable AMPA receptors to control LTP
AM Purkey, KM Woolfrey, KC Crosby, DG Stich, WS Chick, J Aoto, ...
Cell reports 25 (4), 974-987. e4, 2018
752018
Potent antitumor activity of cabozantinib, ac‐MET and VEGFR 2 inhibitor, in a colorectal cancer patient‐derived tumor explant model
EK Song, WM Tai, WA Messersmith, S Bagby, A Purkey, KS Quackenbush, ...
International journal of cancer 136 (8), 1967-1975, 2015
532015
Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer
TM Pitts, TP Newton, EL Bradshaw-Pierce, R Addison, JJ Arcaroli, ...
PloS one 9 (11), e113037, 2014
532014
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer
JJ Arcaroli, WM Tai, R McWilliams, S Bagby, PJ Blatchford, ...
International journal of cancer 138 (1), 195-205, 2016
492016
Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model
JJ Arcaroli, KS Quackenbush, A Purkey, RW Powell, TM Pitts, S Bagby, ...
British journal of cancer 109 (3), 667-675, 2013
432013
Estimating the sex-specific effects of genes on facial attractiveness and sexual dimorphism
DG Mitchem, AM Purkey, NM Grebe, G Carey, CE Garver-Apgar, ...
Behavior Genetics 44, 270-281, 2014
392014
The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance
KS Quackenbush, S Bagby, WM Tai, WA Messersmith, A Schreiber, ...
Oncotarget 7 (19), 28273, 2016
382016
Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model
AJ Scott, EK Song, S Bagby, A Purkey, M McCarter, C Gajdos, ...
PLoS One 12 (11), e0187173, 2017
372017
Local miRNA-dependent translational control of GABAAR synthesis during inhibitory long-term potentiation
D Rajgor, AM Purkey, JL Sanderson, TM Welle, JD Garcia, ML Dell’Acqua, ...
Cell reports 31 (12), 2020
362020
Aldehyde dehydrogenase 1B1 as a modulator of pancreatic adenocarcinoma
S Singh, JJ Arcaroli, DJ Orlicky, Y Chen, WA Messersmith, S Bagby, ...
Pancreas 45 (1), 117-122, 2016
292016
Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer
TM Pitts, EL Bradshaw, SM Bagby, SL Hyatt, HM Selby, A Spreafico, ...
Oncotarget 7 (31), 50290, 2016
282016
Cnksr2 loss in mice leads to increased neural activity and behavioral phenotypes of epilepsy-aphasia syndrome
E Erata, Y Gao, AM Purkey, EJ Soderblom, JO McNamara, SH Soderling
Journal of Neuroscience 41 (46), 9633-9649, 2021
172021
A-kinase anchoring protein 79/150 recruits protein kinase C to phosphorylate roundabout receptors
BK Samelson, BB Gore, JL Whiting, PJ Nygren, AM Purkey, M Colledge, ...
Journal of Biological Chemistry 290 (22), 14107-14119, 2015
162015
Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer
PJ Klauck, SM Bagby, A Capasso, EL Bradshaw-Pierce, HM Selby, ...
BMC cancer 18, 1-12, 2018
152018
Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines
X Chen, KC Crosby, A Feng, AM Purkey, MA Aronova, CA Winters, ...
Frontiers in Synaptic Neuroscience 14, 1004154, 2022
112022
A ventromedial prefrontal-to-lateral entorhinal cortex pathway modulates the gain of behavioral responding during threat
E Hisey, A Purkey, Y Gao, K Hossain, SH Soderling, KJ Ressler
Biological psychiatry 94 (3), 239-248, 2023
62023
Understanding the role of AKAP150 palmitoylation in synaptic plasticity
AM Purkey
University of Colorado Denver, Anschutz Medical Campus, 2019
2019
KRAS wild type tumors exhibit increased efficacy to the combination of AZ1 (a tankyrase inhibitor) plus irinotecan in a patient-derived CRC explant model.
WM Tai, K Quackenbush, A Purkey, S Bagby, W Messersmith, FK Song, ...
MOLECULAR CANCER THERAPEUTICS 12 (11), 2013
2013
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