Chemico-genetic discovery of astrocytic control of inhibition in vivo T Takano, JT Wallace, KT Baldwin, AM Purkey, A Uezu, JL Courtland, ... Nature 588 (7837), 296-302, 2020 | 188 | 2020 |
Phosphorylation-Dependent Regulation of Ca2+-Permeable AMPA Receptors During Hippocampal Synaptic Plasticity AM Purkey, ML Dell’Acqua Frontiers in synaptic neuroscience 12, 8, 2020 | 102 | 2020 |
AKAP150 palmitoylation regulates synaptic incorporation of Ca2+-permeable AMPA receptors to control LTP AM Purkey, KM Woolfrey, KC Crosby, DG Stich, WS Chick, J Aoto, ... Cell reports 25 (4), 974-987. e4, 2018 | 75 | 2018 |
Potent antitumor activity of cabozantinib, ac‐MET and VEGFR 2 inhibitor, in a colorectal cancer patient‐derived tumor explant model EK Song, WM Tai, WA Messersmith, S Bagby, A Purkey, KS Quackenbush, ... International journal of cancer 136 (8), 1967-1975, 2015 | 53 | 2015 |
Dual pharmacological targeting of the MAP kinase and PI3K/mTOR pathway in preclinical models of colorectal cancer TM Pitts, TP Newton, EL Bradshaw-Pierce, R Addison, JJ Arcaroli, ... PloS one 9 (11), e113037, 2014 | 53 | 2014 |
A NOTCH1 gene copy number gain is a prognostic indicator of worse survival and a predictive biomarker to a Notch1 targeting antibody in colorectal cancer JJ Arcaroli, WM Tai, R McWilliams, S Bagby, PJ Blatchford, ... International journal of cancer 138 (1), 195-205, 2016 | 49 | 2016 |
Tumours with elevated levels of the Notch and Wnt pathways exhibit efficacy to PF-03084014, a γ-secretase inhibitor, in a preclinical colorectal explant model JJ Arcaroli, KS Quackenbush, A Purkey, RW Powell, TM Pitts, S Bagby, ... British journal of cancer 109 (3), 667-675, 2013 | 43 | 2013 |
Estimating the sex-specific effects of genes on facial attractiveness and sexual dimorphism DG Mitchem, AM Purkey, NM Grebe, G Carey, CE Garver-Apgar, ... Behavior Genetics 44, 270-281, 2014 | 39 | 2014 |
The novel tankyrase inhibitor (AZ1366) enhances irinotecan activity in tumors that exhibit elevated tankyrase and irinotecan resistance KS Quackenbush, S Bagby, WM Tai, WA Messersmith, A Schreiber, ... Oncotarget 7 (19), 28273, 2016 | 38 | 2016 |
Evaluation of the efficacy of dasatinib, a Src/Abl inhibitor, in colorectal cancer cell lines and explant mouse model AJ Scott, EK Song, S Bagby, A Purkey, M McCarter, C Gajdos, ... PLoS One 12 (11), e0187173, 2017 | 37 | 2017 |
Local miRNA-dependent translational control of GABAAR synthesis during inhibitory long-term potentiation D Rajgor, AM Purkey, JL Sanderson, TM Welle, JD Garcia, ML Dell’Acqua, ... Cell reports 31 (12), 2020 | 36 | 2020 |
Aldehyde dehydrogenase 1B1 as a modulator of pancreatic adenocarcinoma S Singh, JJ Arcaroli, DJ Orlicky, Y Chen, WA Messersmith, S Bagby, ... Pancreas 45 (1), 117-122, 2016 | 29 | 2016 |
Antitumor activity of the aurora a selective kinase inhibitor, alisertib, against preclinical models of colorectal cancer TM Pitts, EL Bradshaw, SM Bagby, SL Hyatt, HM Selby, A Spreafico, ... Oncotarget 7 (31), 50290, 2016 | 28 | 2016 |
Cnksr2 loss in mice leads to increased neural activity and behavioral phenotypes of epilepsy-aphasia syndrome E Erata, Y Gao, AM Purkey, EJ Soderblom, JO McNamara, SH Soderling Journal of Neuroscience 41 (46), 9633-9649, 2021 | 17 | 2021 |
A-kinase anchoring protein 79/150 recruits protein kinase C to phosphorylate roundabout receptors BK Samelson, BB Gore, JL Whiting, PJ Nygren, AM Purkey, M Colledge, ... Journal of Biological Chemistry 290 (22), 14107-14119, 2015 | 16 | 2015 |
Antitumor activity of the polo-like kinase inhibitor, TAK-960, against preclinical models of colorectal cancer PJ Klauck, SM Bagby, A Capasso, EL Bradshaw-Pierce, HM Selby, ... BMC cancer 18, 1-12, 2018 | 15 | 2018 |
Palmitoylation of A-kinase anchoring protein 79/150 modulates its nanoscale organization, trafficking, and mobility in postsynaptic spines X Chen, KC Crosby, A Feng, AM Purkey, MA Aronova, CA Winters, ... Frontiers in Synaptic Neuroscience 14, 1004154, 2022 | 11 | 2022 |
A ventromedial prefrontal-to-lateral entorhinal cortex pathway modulates the gain of behavioral responding during threat E Hisey, A Purkey, Y Gao, K Hossain, SH Soderling, KJ Ressler Biological psychiatry 94 (3), 239-248, 2023 | 6 | 2023 |
Understanding the role of AKAP150 palmitoylation in synaptic plasticity AM Purkey University of Colorado Denver, Anschutz Medical Campus, 2019 | | 2019 |
KRAS wild type tumors exhibit increased efficacy to the combination of AZ1 (a tankyrase inhibitor) plus irinotecan in a patient-derived CRC explant model. WM Tai, K Quackenbush, A Purkey, S Bagby, W Messersmith, FK Song, ... MOLECULAR CANCER THERAPEUTICS 12 (11), 2013 | | 2013 |