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Stephan Hirschi
Stephan Hirschi
Postdoctoral Research Associate, University of Oxford
bioch.ox.ac.uk의 이메일 확인됨
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Synthetic biology: bottom-up assembly of molecular systems
S Hirschi, TR Ward, WP Meier, DJ Müller, D Fotiadis
Chemical reviews 122 (21), 16294-16328, 2022
832022
Fusion domains guide the oriented insertion of light-driven proton pumps into liposomes
N Ritzmann, J Thoma, S Hirschi, D Kalbermatter, D Fotiadis, DJ Müller
Biophysical journal 113 (6), 1181-1186, 2017
442017
Directed insertion of light-activated proteorhodopsin into asymmetric polymersomes from an ABC block copolymer
J Gaitzsch, S Hirschi, S Freimann, D Fotiadis, W Meier
Nano letters 19 (4), 2503-2508, 2019
412019
Cryo-EM structure and dynamics of the green-light absorbing proteorhodopsin
S Hirschi, D Kalbermatter, Z Ucurum, T Lemmin, D Fotiadis
Nature communications 12 (1), 4107, 2021
272021
Engineering a Chemical Switch into the Light‐driven Proton Pump Proteorhodopsin by Cysteine Mutagenesis and Thiol Modification
D Harder, S Hirschi, Z Ucurum, R Goers, W Meier, DJ Müller, D Fotiadis
Angewandte Chemie International Edition 55 (31), 8846-8849, 2016
272016
Structural and biochemical insights into His-tag-induced higher-order oligomerization of membrane proteins by cryo-EM and size exclusion chromatography
N Ayoub, P Roth, Z Ucurum, D Fotiadis, S Hirschi
Journal of structural biology 215 (1), 107924, 2023
162023
Erythrocyte invasion-neutralising antibodies prevent Plasmodium falciparum RH5 from binding to basigin-containing membrane protein complexes
A Jamwal, CF Constantin, S Hirschi, S Henrich, W Bildl, B Fakler, ...
Elife 12, e83681, 2023
132023
Engineering and assembly of protein modules into functional molecular systems
S Hirschi, M Stauffer, D Harder, DJ Müller, W Meier, D Fotiadis
Chimia 70 (6), 398-398, 2016
132016
Engineering and Production of the Light-Driven Proton Pump Bacteriorhodopsin in 2D Crystals for Basic Research and Applied Technologies
M Stauffer, S Hirschi, Z Ucurum, D Harder, R Schlesinger, D Fotiadis
Methods and protocols 3 (3), 51, 2020
112020
Cryo-electron microscopic and X-ray crystallographic analysis of the light-driven proton pump proteorhodopsin reveals a pentameric assembly
S Hirschi, D Kalbermatter, Z Ucurum, D Fotiadis
Journal of structural biology: X 4, 100024, 2020
112020
Design and assembly of a chemically switchable and fluorescently traceable light-driven proton pump system for bionanotechnological applications
S Hirschi, N Fischer, D Kalbermatter, PR Laskowski, Z Ucurum, DJ Müller, ...
Scientific reports 9 (1), 1046, 2019
102019
Purification of membrane proteins by affinity chromatography with on-column protease cleavage
S Hirschi, D Fotiadis
Expression, Purification, and Structural Biology of Membrane Proteins, 139-150, 2020
92020
Expression, purification and crystallization of an SLC16 monocarboxylate transporter family homologue specific for l-lactate
S Bonetti, S Hirschi, PD Bosshart
Protein expression and purification 165, 105484, 2020
82020
Purification of Human and Mammalian Membrane Proteins Expressed in Xenopus laevis Frog Oocytes for Structural Studies
R Boggavarapu, S Hirschi, D Harder, M Meury, Z Ucurum, MJ Bergeron, ...
Heterologous Expression of Membrane Proteins: Methods and Protocols, 223-242, 2016
22016
Structural insights into the mechanism and dynamics of proteorhodopsin biogenesis and retinal scavenging
S Hirschi, T Lemmin, N Ayoub, D Kalbermatter, D Pellegata, Z Ucurum, ...
Nature Communications 15 (1), 6950, 2024
12024
Actinorhodopsin: an efficient and robust light-driven proton pump for bionanotechnological applications
N Ayoub, N Djabeur, D Harder, JM Jeckelmann, Z Ucurum, S Hirschi, ...
Scientific Reports 15 (1), 4054, 2025
2025
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