| Generation of functional human hepatic endoderm from human induced pluripotent stem cells GJ Sullivan, DC Hay, IH Park, J Fletcher, Z Hannoun, CM Payne, ... Hepatology 51 (1), 329-335, 2010 | 586 | 2010 |
| Efficient differentiation of hepatocytes from human embryonic stem cells exhibiting markers recapitulating liver development in vivo DC Hay, D Zhao, J Fletcher, ZA Hewitt, D McLean, ... Stem cells 26 (4), 894-902, 2008 | 555 | 2008 |
| Highly efficient differentiation of hESCs to functional hepatic endoderm requires ActivinA and Wnt3a signaling DC Hay, J Fletcher, C Payne, JD Terrace, RCJ Gallagher, J Snoeys, ... Proceedings of the National Academy of Sciences 105 (34), 12301-12306, 2008 | 535 | 2008 |
| Oct‐4 knockdown induces similar patterns of endoderm and trophoblast differentiation markers in human and mouse embryonic stem cells DC Hay, L Sutherland, J Clark, T Burdon Stem cells 22 (2), 225-235, 2004 | 531 | 2004 |
| Hepatic progenitor cells of biliary origin with liver repopulation capacity WY Lu, TG Bird, L Boulter, A Tsuchiya, AM Cole, T Hay, RV Guest, ... Nature cell biology 17 (8), 971-983, 2015 | 485 | 2015 |
| Lineage-specific distribution of high levels of genomic A Ruzov, Y Tsenkina, A Serio, T Dudnakova, J Fletcher, Y Bai, ... Cell research 21 (9), 1332-1342, 2011 | 238 | 2011 |
| Direct differentiation of human embryonic stem cells to hepatocyte-like cells exhibiting functional activities DC Hay, D Zhao, A Ross, R Mandalam, J Lebkowski, W Cui Cloning and stem cells 9 (1), 51-62, 2007 | 233 | 2007 |
| Gene networks and transcription factor motifs defining the differentiation of stem cells into hepatocyte-like cells P Godoy, W Schmidt-Heck, K Natarajan, B Lucendo-Villarin, D Szkolnicka, ... Journal of hepatology 63 (4), 934-942, 2015 | 203 | 2015 |
| Liver tissue engineering and cell sources: issues and challenges AA Palakkan, DC Hay, AK PR, K TV, JA Ross Liver international 33 (5), 666-676, 2013 | 163 | 2013 |
| Recombinant laminins drive the differentiation and self-organization of hESC-derived hepatocytes K Cameron, R Tan, W Schmidt-Heck, G Campos, MJ Lyall, Y Wang, ... Stem cell reports 5 (6), 1250-1262, 2015 | 161 | 2015 |
| Post-translational modification by SUMO Z Hannoun, S Greenhough, E Jaffray, RT Hay, DC Hay Toxicology 278 (3), 288-293, 2010 | 160 | 2010 |
| Developing high-fidelity hepatotoxicity models from pluripotent stem cells CN Medine, B Lucendo-Villarin, C Storck, F Wang, D Szkolnicka, F Khan, ... Stem cells translational medicine 2 (7), 505-509, 2013 | 158 | 2013 |
| Concise review: workshop review: understanding and assessing the risks of stem cell-based therapies JA Heslop, TG Hammond, I Santeramo, A Tort Piella, I Hopp, J Zhou, ... Stem cells translational medicine 4 (4), 389-400, 2015 | 149 | 2015 |
| Mechanistic evaluation of primary human hepatocyte culture using global proteomic analysis reveals a selective dedifferentiation profile JA Heslop, C Rowe, J Walsh, R Sison-Young, R Jenkins, L Kamalian, ... Archives of toxicology 91, 439-452, 2017 | 145 | 2017 |
| Accurate prediction of drug-induced liver injury using stem cell-derived populations D Szkolnicka, SL Farnworth, B Lucendo-Villarin, C Storck, W Zhou, ... Stem cells translational medicine 3 (2), 141-148, 2014 | 130 | 2014 |
| Fluid shear stress modulation of hepatocyte-like cell function H Rashidi, S Alhaque, D Szkolnicka, O Flint, DC Hay Archives of toxicology 90, 1757-1761, 2016 | 127 | 2016 |
| Unbiased screening of polymer libraries to define novel substrates for functional hepatocytes with inducible drug metabolism DC Hay, S Pernagallo, JJ Diaz-Mochon, CN Medine, S Greenhough, ... Stem cell research 6 (2), 92-102, 2011 | 125 | 2011 |
| 3D human liver tissue from pluripotent stem cells displays stable phenotype in vitro and supports compromised liver function in vivo H Rashidi, NT Luu, SM Alwahsh, M Ginai, S Alhaque, H Dong, RA Tomaz, ... Archives of toxicology 92, 3117-3129, 2018 | 122 | 2018 |
| Progress and future challenges in stem cell-derived liver technologies DM Dalgetty, CN Medine, JP Iredale, DC Hay American Journal of Physiology-Gastrointestinal and Liver Physiology 297 (2 …, 2009 | 119 | 2009 |
| Blended electrospinning with human liver extracellular matrix for engineering new hepatic microenvironments R Grant, J Hallett, S Forbes, D Hay, A Callanan Scientific reports 9 (1), 6293, 2019 | 101 | 2019 |