ABC transporters in multidrug resistance and pharmacokinetics, and strategies for drug development Y Hee Choi, AM Yu Current pharmaceutical design 20 (5), 793-807, 2014 | 654 | 2014 |
MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells YZ Pan, ME Morris, AM Yu Molecular pharmacology 75 (6), 1374-1379, 2009 | 389 | 2009 |
RNA drugs and RNA targets for small molecules: principles, progress, and challenges AM Yu, YH Choi, MJ Tu Pharmacological reviews 72 (4), 862-898, 2020 | 336 | 2020 |
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting YZ Pan, W Gao, AM Yu Drug metabolism and disposition 37 (10), 2112-2117, 2009 | 327 | 2009 |
Current trends in drug metabolism and pharmacokinetics Y Li, Q Meng, M Yang, D Liu, X Hou, L Tang, X Wang, Y Lyu, X Chen, ... Acta Pharmaceutica Sinica B 9 (6), 1113-1144, 2019 | 283 | 2019 |
Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6 AM Yu, JR Idle, LG Byrd, KW Krausz, A Küpfer, FJ Gonzalez Pharmacogenetics and Genomics 13 (3), 173-181, 2003 | 221 | 2003 |
Psychedelic 5-methoxy-N, N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions HW Shen, XL Jiang, J C Winter, AM Yu Current drug metabolism 11 (8), 659-666, 2010 | 209 | 2010 |
miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes AE Bruno, L Li, JL Kalabus, Y Pan, A Yu, Z Hu BMC genomics 13, 1-7, 2012 | 204 | 2012 |
Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CYP2D6 and CYP3A activities? A Yu, RL Haining Drug Metabolism and Disposition 29 (11), 1514-1520, 2001 | 199 | 2001 |
Cytochrome P450 and xenobiotic receptor humanized mice FJ Gonzalez, AM Yu Annu. Rev. Pharmacol. Toxicol. 46 (1), 41-64, 2006 | 196 | 2006 |
The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity C Cheung, AM Yu, JM Ward, KW Krausz, TE Akiyama, L Feigenbaum, ... Drug metabolism and disposition 33 (3), 449-457, 2005 | 195 | 2005 |
Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase AM Yu, JR Idle, T Herraiz, A Küpfer, FJ Gonzalez Pharmacogenetics and Genomics 13 (6), 307-319, 2003 | 170 | 2003 |
RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies GM Traber, AM Yu Journal of Pharmacology and Experimental Therapeutics 384 (1), 133-154, 2023 | 167 | 2023 |
Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4α Y Inoue, AM Yu, SH Yim, X Ma, KW Krausz, J Inoue, CC Xiang, ... Journal of lipid research 47 (1), 215-227, 2006 | 166 | 2006 |
Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328,-519c and-520h) and their differential expression in stem-like ABCG2+ cancer cells X Li, YZ Pan, GM Seigel, ZH Hu, M Huang, AM Yu Biochemical pharmacology 81 (6), 783-792, 2011 | 163 | 2011 |
RNA therapy: Are we using the right molecules? AM Yu, C Jian, HY Allan, MJ Tu Pharmacology & therapeutics 196, 91-104, 2019 | 162 | 2019 |
Contribution of Individual Cytochrome P450 Isozymes to theO-Demethylation of the Psychotropic β-Carboline Alkaloids Harmaline and Harmine AM Yu, JR Idle, KW Krausz, A Küpfer, FJ Gonzalez Journal of Pharmacology and Experimental Therapeutics 305 (1), 315-322, 2003 | 150 | 2003 |
Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates AM Yu, JR Idle, FJ Gonzalez Drug metabolism reviews 36 (2), 243-277, 2004 | 141 | 2004 |
Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam CP Granvil, AM Yu, G Elizondo, TE Akiyama, C Cheung, L Feigenbaum, ... Drug metabolism and disposition 31 (5), 548-558, 2003 | 134 | 2003 |
Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6. 1, 2D6. 2, 2D6. 10, and 2D6. 17 allelic isoforms A Yu, BM Kneller, AE Rettie, RL Haining Journal of Pharmacology and Experimental Therapeutics 303 (3), 1291-1300, 2002 | 129 | 2002 |