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Aiming Yu
Aiming Yu
Professor of Biochemistry and Molecular Medicine, University of California, Davis
ucdavis.edu의 이메일 확인됨
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ABC transporters in multidrug resistance and pharmacokinetics, and strategies for drug development
Y Hee Choi, AM Yu
Current pharmaceutical design 20 (5), 793-807, 2014
6542014
MicroRNA-328 negatively regulates the expression of breast cancer resistance protein (BCRP/ABCG2) in human cancer cells
YZ Pan, ME Morris, AM Yu
Molecular pharmacology 75 (6), 1374-1379, 2009
3892009
RNA drugs and RNA targets for small molecules: principles, progress, and challenges
AM Yu, YH Choi, MJ Tu
Pharmacological reviews 72 (4), 862-898, 2020
3362020
MicroRNAs regulate CYP3A4 expression via direct and indirect targeting
YZ Pan, W Gao, AM Yu
Drug metabolism and disposition 37 (10), 2112-2117, 2009
3272009
Current trends in drug metabolism and pharmacokinetics
Y Li, Q Meng, M Yang, D Liu, X Hou, L Tang, X Wang, Y Lyu, X Chen, ...
Acta Pharmaceutica Sinica B 9 (6), 1113-1144, 2019
2832019
Regeneration of serotonin from 5-methoxytryptamine by polymorphic human CYP2D6
AM Yu, JR Idle, LG Byrd, KW Krausz, A Küpfer, FJ Gonzalez
Pharmacogenetics and Genomics 13 (3), 173-181, 2003
2212003
Psychedelic 5-methoxy-N, N-dimethyltryptamine: metabolism, pharmacokinetics, drug interactions, and pharmacological actions
HW Shen, XL Jiang, J C Winter, AM Yu
Current drug metabolism 11 (8), 659-666, 2010
2092010
miRdSNP: a database of disease-associated SNPs and microRNA target sites on 3'UTRs of human genes
AE Bruno, L Li, JL Kalabus, Y Pan, A Yu, Z Hu
BMC genomics 13, 1-7, 2012
2042012
Comparative contribution to dextromethorphan metabolism by cytochrome P450 isoforms in vitro: can dextromethorphan be used as a dual probe for both CYP2D6 and CYP3A activities?
A Yu, RL Haining
Drug Metabolism and Disposition 29 (11), 1514-1520, 2001
1992001
Cytochrome P450 and xenobiotic receptor humanized mice
FJ Gonzalez, AM Yu
Annu. Rev. Pharmacol. Toxicol. 46 (1), 41-64, 2006
1962006
The cyp2e1-humanized transgenic mouse: role of cyp2e1 in acetaminophen hepatotoxicity
C Cheung, AM Yu, JM Ward, KW Krausz, TE Akiyama, L Feigenbaum, ...
Drug metabolism and disposition 33 (3), 449-457, 2005
1952005
Screening for endogenous substrates reveals that CYP2D6 is a 5-methoxyindolethylamine O-demethylase
AM Yu, JR Idle, T Herraiz, A Küpfer, FJ Gonzalez
Pharmacogenetics and Genomics 13 (6), 307-319, 2003
1702003
RNAi-Based Therapeutics and Novel RNA Bioengineering Technologies
GM Traber, AM Yu
Journal of Pharmacology and Experimental Therapeutics 384 (1), 133-154, 2023
1672023
Regulation of bile acid biosynthesis by hepatocyte nuclear factor 4α
Y Inoue, AM Yu, SH Yim, X Ma, KW Krausz, J Inoue, CC Xiang, ...
Journal of lipid research 47 (1), 215-227, 2006
1662006
Breast cancer resistance protein BCRP/ABCG2 regulatory microRNAs (hsa-miR-328,-519c and-520h) and their differential expression in stem-like ABCG2+ cancer cells
X Li, YZ Pan, GM Seigel, ZH Hu, M Huang, AM Yu
Biochemical pharmacology 81 (6), 783-792, 2011
1632011
RNA therapy: Are we using the right molecules?
AM Yu, C Jian, HY Allan, MJ Tu
Pharmacology & therapeutics 196, 91-104, 2019
1622019
Contribution of Individual Cytochrome P450 Isozymes to theO-Demethylation of the Psychotropic β-Carboline Alkaloids Harmaline and Harmine
AM Yu, JR Idle, KW Krausz, A Küpfer, FJ Gonzalez
Journal of Pharmacology and Experimental Therapeutics 305 (1), 315-322, 2003
1502003
Polymorphic cytochrome P450 2D6: humanized mouse model and endogenous substrates
AM Yu, JR Idle, FJ Gonzalez
Drug metabolism reviews 36 (2), 243-277, 2004
1412004
Expression of the human CYP3A4 gene in the small intestine of transgenic mice: in vitro metabolism and pharmacokinetics of midazolam
CP Granvil, AM Yu, G Elizondo, TE Akiyama, C Cheung, L Feigenbaum, ...
Drug metabolism and disposition 31 (5), 548-558, 2003
1342003
Expression, purification, biochemical characterization, and comparative function of human cytochrome P450 2D6. 1, 2D6. 2, 2D6. 10, and 2D6. 17 allelic isoforms
A Yu, BM Kneller, AE Rettie, RL Haining
Journal of Pharmacology and Experimental Therapeutics 303 (3), 1291-1300, 2002
1292002
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