Increase in single L-type calcium channels in hippocampal neurons during aging O Thibault, PW Landfield Science 272 (5264), 1017-1020, 1996 | 590 | 1996 |
Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store O Thibault, JC Gant, PW Landfield Aging cell 6 (3), 307-317, 2007 | 483 | 2007 |
Elevated Postsynaptic [Ca2+] iand L-Type Calcium Channel Activity in Aged Hippocampal Neurons: Relationship to Impaired Synaptic Plasticity O Thibault, R Hadley, PW Landfield Journal of Neuroscience 21 (24), 9744-9756, 2001 | 329 | 2001 |
Hippocampal glucocorticoid receptor activation enhances voltage-dependent Ca2+ conductances: relevance to brain aging. DS Kerr, LW Campbell, O Thibault, PW Landfield Proceedings of the National Academy of Sciences 89 (18), 8527-8531, 1992 | 302 | 1992 |
Antagonism of NMDA receptors impairs acquisition but not retention of olfactory memory. U Staubli, O Thibault, M DiLorenzo, G Lynch Behavioral neuroscience 103 (1), 54, 1989 | 289 | 1989 |
Vitamin D prevents cognitive decline and enhances hippocampal synaptic function in aging rats CS Latimer, LD Brewer, JL Searcy, KC Chen, J Popović, SD Kraner, ... Proceedings of the National Academy of Sciences 111 (41), E4359-E4366, 2014 | 248 | 2014 |
Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons LW Campbell, SY Hao, O Thibault, EM Blalock, PW Landfield Journal of Neuroscience 16 (19), 6286-6295, 1996 | 248 | 1996 |
Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats WB Rowe, EM Blalock, KC Chen, I Kadish, D Wang, JE Barrett, O Thibault, ... Journal of Neuroscience 27 (12), 3098-3110, 2007 | 245 | 2007 |
Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions O Thibault, NM Porter, KC Chen, EM Blalock, PG Kaminker, GV Clodfelter, ... Cell calcium 24 (5-6), 417-433, 1998 | 218 | 1998 |
Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release JC Gant, MM Sama, PW Landfield, O Thibault Journal of Neuroscience 26 (13), 3482-3490, 2006 | 209 | 2006 |
Calcium hypothesis of Alzheimer's disease and brain aging: a framework for integrating new evidence into a comprehensive theory of pathogenesis Alzheimer's Association Calcium Hypothesis Workgroup, ... Alzheimer's & Dementia 13 (2), 178-182. e17, 2017 | 206 | 2017 |
Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's disease JL Searcy, JT Phelps, T Pancani, I Kadish, J Popovic, KL Anderson, ... Journal of Alzheimer’s Disease 30 (4), 943-961, 2012 | 185 | 2012 |
Reversal of glial and neurovascular markers of unhealthy brain aging by exercise in middle-aged female mice CS Latimer, JL Searcy, MT Bridges, LD Brewer, J Popović, EM Blalock, ... PloS one 6 (10), e26812, 2011 | 181 | 2011 |
Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment I Kadish, O Thibault, EM Blalock, KC Chen, JC Gant, NM Porter, ... Journal of Neuroscience 29 (6), 1805-1816, 2009 | 179 | 2009 |
Calcium channel density and hippocampal cell death with age in long-term culture NM Porter, O Thibault, V Thibault, KC Chen, PW Landfield Journal of Neuroscience 17 (14), 5629-5639, 1997 | 165 | 1997 |
Mechanisms of neuronal death in brain aging and Alzheimer's disease: role of endocrine‐mediated calcium dyshomeostasis PW Landfield, O Thibault, ML Mazzanti, NM Porter, DS Kerr Journal of neurobiology 23 (9), 1247-1260, 1992 | 152 | 1992 |
The neurobiology of aging KM Kelly, NL Nadon, JH Morrison, O Thibault, CA Barnes, EM Blalock Epilepsy research 68, 5-20, 2006 | 150 | 2006 |
Chronic administration of a thiol-proteinase inhibitor blocks long-term potentiation of synaptic responses U Staubli, J Larson, O Thibault, M Baudry, G Lynch Brain research 444 (1), 153-158, 1988 | 128 | 1988 |
Chronic 1α, 25-(OH) 2vitamin D3 treatment reduces Ca2+-mediated hippocampal biomarkers of aging LD Brewer, NM Porter, DS Kerr, PW Landfield, O Thibault Cell calcium 40 (3), 277-286, 2006 | 119 | 2006 |
Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L … LD Brewer, O Thibault, J Staton, V Thibault, JT Rogers, G Garcia-Ramos, ... Brain research 1151, 20-31, 2007 | 111 | 2007 |