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Olivier Thibault
Olivier Thibault
Pharmacology
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Increase in single L-type calcium channels in hippocampal neurons during aging
O Thibault, PW Landfield
Science 272 (5264), 1017-1020, 1996
5901996
Expansion of the calcium hypothesis of brain aging and Alzheimer's disease: minding the store
O Thibault, JC Gant, PW Landfield
Aging cell 6 (3), 307-317, 2007
4832007
Elevated Postsynaptic [Ca2+] iand L-Type Calcium Channel Activity in Aged Hippocampal Neurons: Relationship to Impaired Synaptic Plasticity
O Thibault, R Hadley, PW Landfield
Journal of Neuroscience 21 (24), 9744-9756, 2001
3292001
Hippocampal glucocorticoid receptor activation enhances voltage-dependent Ca2+ conductances: relevance to brain aging.
DS Kerr, LW Campbell, O Thibault, PW Landfield
Proceedings of the National Academy of Sciences 89 (18), 8527-8531, 1992
3021992
Antagonism of NMDA receptors impairs acquisition but not retention of olfactory memory.
U Staubli, O Thibault, M DiLorenzo, G Lynch
Behavioral neuroscience 103 (1), 54, 1989
2891989
Vitamin D prevents cognitive decline and enhances hippocampal synaptic function in aging rats
CS Latimer, LD Brewer, JL Searcy, KC Chen, J Popović, SD Kraner, ...
Proceedings of the National Academy of Sciences 111 (41), E4359-E4366, 2014
2482014
Aging changes in voltage-gated calcium currents in hippocampal CA1 neurons
LW Campbell, SY Hao, O Thibault, EM Blalock, PW Landfield
Journal of Neuroscience 16 (19), 6286-6295, 1996
2481996
Hippocampal expression analyses reveal selective association of immediate-early, neuroenergetic, and myelinogenic pathways with cognitive impairment in aged rats
WB Rowe, EM Blalock, KC Chen, I Kadish, D Wang, JE Barrett, O Thibault, ...
Journal of Neuroscience 27 (12), 3098-3110, 2007
2452007
Calcium dysregulation in neuronal aging and Alzheimer's disease: history and new directions
O Thibault, NM Porter, KC Chen, EM Blalock, PG Kaminker, GV Clodfelter, ...
Cell calcium 24 (5-6), 417-433, 1998
2181998
Early and simultaneous emergence of multiple hippocampal biomarkers of aging is mediated by Ca2+-induced Ca2+ release
JC Gant, MM Sama, PW Landfield, O Thibault
Journal of Neuroscience 26 (13), 3482-3490, 2006
2092006
Calcium hypothesis of Alzheimer's disease and brain aging: a framework for integrating new evidence into a comprehensive theory of pathogenesis
Alzheimer's Association Calcium Hypothesis Workgroup, ...
Alzheimer's & Dementia 13 (2), 178-182. e17, 2017
2062017
Long-term pioglitazone treatment improves learning and attenuates pathological markers in a mouse model of Alzheimer's disease
JL Searcy, JT Phelps, T Pancani, I Kadish, J Popovic, KL Anderson, ...
Journal of Alzheimer’s Disease 30 (4), 943-961, 2012
1852012
Reversal of glial and neurovascular markers of unhealthy brain aging by exercise in middle-aged female mice
CS Latimer, JL Searcy, MT Bridges, LD Brewer, J Popović, EM Blalock, ...
PloS one 6 (10), e26812, 2011
1812011
Hippocampal and cognitive aging across the lifespan: a bioenergetic shift precedes and increased cholesterol trafficking parallels memory impairment
I Kadish, O Thibault, EM Blalock, KC Chen, JC Gant, NM Porter, ...
Journal of Neuroscience 29 (6), 1805-1816, 2009
1792009
Calcium channel density and hippocampal cell death with age in long-term culture
NM Porter, O Thibault, V Thibault, KC Chen, PW Landfield
Journal of Neuroscience 17 (14), 5629-5639, 1997
1651997
Mechanisms of neuronal death in brain aging and Alzheimer's disease: role of endocrine‐mediated calcium dyshomeostasis
PW Landfield, O Thibault, ML Mazzanti, NM Porter, DS Kerr
Journal of neurobiology 23 (9), 1247-1260, 1992
1521992
The neurobiology of aging
KM Kelly, NL Nadon, JH Morrison, O Thibault, CA Barnes, EM Blalock
Epilepsy research 68, 5-20, 2006
1502006
Chronic administration of a thiol-proteinase inhibitor blocks long-term potentiation of synaptic responses
U Staubli, J Larson, O Thibault, M Baudry, G Lynch
Brain research 444 (1), 153-158, 1988
1281988
Chronic 1α, 25-(OH) 2vitamin D3 treatment reduces Ca2+-mediated hippocampal biomarkers of aging
LD Brewer, NM Porter, DS Kerr, PW Landfield, O Thibault
Cell calcium 40 (3), 277-286, 2006
1192006
Increased vulnerability of hippocampal neurons with age in culture: temporal association with increases in NMDA receptor current, NR2A subunit expression and recruitment of L …
LD Brewer, O Thibault, J Staton, V Thibault, JT Rogers, G Garcia-Ramos, ...
Brain research 1151, 20-31, 2007
1112007
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