Survivin-targeted immunotherapy drives robust polyfunctional T cell generation and differentiation in advanced ovarian cancer patients NL Berinstein, M Karkada, AM Oza, K Odunsi, JA Villella, JJ Nemunaitis, ... Oncoimmunology 4 (8), e1026529, 2015 | 105 | 2015 |
Immune modulation by chemotherapy or immunotherapy to enhance cancer vaccines GM Weir, RS Liwski, M Mansour Cancers 3 (3), 3114-3142, 2011 | 99 | 2011 |
First-in-man application of a novel therapeutic cancer vaccine formulation with the capacity to induce multi-functional T cell responses in ovarian, breast and prostate cancer … NL Berinstein, M Karkada, MA Morse, JJ Nemunaitis, G Chatta, ... Journal of translational medicine 10, 1-12, 2012 | 95 | 2012 |
Therapy of established B16-F10 melanoma tumors by a single vaccination of CTL/T helper peptides in VacciMax® M Mansour, B Pohajdak, WM Kast, A Fuentes-Ortega, E Korets-Smith, ... Journal of Translational Medicine 5, 1-8, 2007 | 85 | 2007 |
Rejection of large HPV-16 expressing tumors in aged mice by a single immunization of VacciMax® encapsulated CTL/T helper peptides PM Daftarian, M Mansour, B Pohajdak, A Fuentes-Ortega, E Korets-Smith, ... Journal of translational medicine 5, 1-8, 2007 | 63 | 2007 |
A liposome-based platform, VacciMax®, and its modified water-free platform DepoVax™ enhance efficacy of in vivo nucleic acid delivery M Karkada, GM Weir, T Quinton, A Fuentes-Ortega, M Mansour Vaccine 28 (38), 6176-6182, 2010 | 62 | 2010 |
A respiratory syncytial virus vaccine based on the small hydrophobic protein ectodomain presented with a novel lipid-based formulation is highly immunogenic and safe in adults … JM Langley, LD MacDonald, GM Weir, D MacKinnon-Cameron, L Ye, ... The Journal of infectious diseases 218 (3), 378-387, 2018 | 52 | 2018 |
A novel breast/ovarian cancer peptide vaccine platform that promotes specific type-1 but not Treg/Tr1-type responses M Karkada, GM Weir, T Quinton, L Sammatur, LD MacDonald, A Grant, ... Journal of immunotherapy 33 (3), 250-261, 2010 | 51 | 2010 |
Metronomic cyclophosphamide enhances HPV16E7 peptide vaccine induced antigen-specific and cytotoxic T-cell mediated antitumor immune response GM Weir, O Hrytsenko, MM Stanford, NL Berinstein, M Karkada, RS Liwski, ... Oncoimmunology 3 (8), e953407, 2014 | 43 | 2014 |
Clearance of depot vaccine SPIO-labeled antigen and substrate visualized using MRI KD Brewer, K Lake, N Pelot, MM Stanford, DR DeBay, A Penwell, ... Vaccine 32 (51), 6956-6962, 2014 | 38 | 2014 |
Using MRI cell tracking to monitor immune cell recruitment in response to a peptide‐based cancer vaccine ML Tremblay, C Davis, CV Bowen, O Stanley, C Parsons, G Weir, ... Magnetic Resonance in Medicine 80 (1), 304-316, 2018 | 37 | 2018 |
Anti-PD-1 increases the clonality and activity of tumor infiltrating antigen specific T cells induced by a potent immune therapy consisting of vaccine and metronomic … GM Weir, O Hrytsenko, T Quinton, NL Berinstein, MM Stanford, ... Journal for immunotherapy of cancer 4, 1-13, 2016 | 36 | 2016 |
Unique depot formed by an oil based vaccine facilitates active antigen uptake and provides effective tumour control KD Brewer, GM Weir, I Dude, C Davis, C Parsons, A Penwell, ... Journal of Biomedical Science 25, 1-12, 2018 | 31 | 2018 |
Combination of poly I:C and Pam3CSK4 enhances activation of B cells in vitro and boosts antibody responses to protein vaccines in vivo GM Weir, M Karkada, D Hoskin, MM Stanford, L MacDonald, M Mansour, ... PLoS One 12 (6), e0180073, 2017 | 30 | 2017 |
Novel peptide-based PD1 immunomodulators demonstrate efficacy in infectious disease vaccines and therapeutics V Kotraiah, TW Phares, CD Browne, J Pannucci, M Mansour, AR Noe, ... Frontiers in Immunology 11, 264, 2020 | 26 | 2020 |
Single dose of DPX-rPA, an enhanced-delivery anthrax vaccine formulation, protects against a lethal Bacillusanthracis spore inhalation challenge GM Weir, LD MacDonald, R Rajagopalan, GS Sivko, MW Valderas, ... npj Vaccines 4 (1), 6, 2019 | 21 | 2019 |
Compositions comprising liposomes, an antigen, a polynucleotide and a carrier comprising a continuous phase of a hydrophobic substance M Mansour, L Sammatur, LD MacDonald, M Karkada, GM Weir, ... US Patent App. 12/992,512, 2011 | 18 | 2011 |
Using lymph node swelling as a potential biomarker for successful vaccination KD Brewer, DR DeBay, I Dude, C Davis, K Lake, C Parsons, ... Oncotarget 7 (24), 35655, 2016 | 15 | 2016 |
Use of liposomes in a carrier comprising a continuous hydrophobic phase for delivery of polynucleotides in vivo M Mansour, M Karkada, GM Weir US Patent 9,498,493, 2016 | 13 | 2016 |
Liposome compositions comprising an adjuvant that activates or increases the activity of TLR2 and uses thereof M Mansour, LD MacDonald, GM Weir, L Sammatur, K Sharp US Patent 10,105,435, 2018 | 10 | 2018 |