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Luisella Spiga
Luisella Spiga
Vanderbilt University Medical Center (VUMC)
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Precision editing of the gut microbiota ameliorates colitis
W Zhu, MG Winter, MX Byndloss, L Spiga, BA Duerkop, ER Hughes, ...
Nature 553 (7687), 208-211, 2018
5072018
Microbial respiration and formate oxidation as metabolic signatures of inflammation-associated dysbiosis
ER Hughes, MG Winter, BA Duerkop, L Spiga, TF de Carvalho, W Zhu, ...
Cell host & microbe 21 (2), 208-219, 2017
3272017
Dysbiosis-associated change in host metabolism generates lactate to support Salmonella growth
CC Gillis, ER Hughes, L Spiga, MG Winter, W Zhu, TF de Carvalho, ...
Cell host & microbe 23 (1), 54-64. e6, 2018
2412018
Respiration of Microbiota-Derived 1,2-propanediol Drives Salmonella Expansion during Colitis
F Faber, P Thiennimitr, L Spiga, MX Byndloss, Y Litvak, S Lawhon, ...
PLoS pathogens 13 (1), e1006129, 2017
2002017
An oxidative central metabolism enables Salmonella to utilize microbiota-derived succinate
L Spiga, MG Winter, TF de Carvalho, W Zhu, ER Hughes, CC Gillis, ...
Cell host & microbe 22 (3), 291-301. e6, 2017
1692017
Editing of the gut microbiota reduces carcinogenesis in mouse models of colitis-associated colorectal cancer
W Zhu, N Miyata, MG Winter, A Arenales, ER Hughes, L Spiga, J Kim, ...
Journal of experimental medicine 216 (10), 2378-2393, 2019
1072019
Staphylococcus aureus and Staphylococcus epidermidis Virulence Strains as Causative Agents of Persistent Infections in Breast Implants
D Chessa, G Ganau, L Spiga, A Bulla, V Mazzarello, GV Campus, ...
PLoS One 11 (1), e0146668, 2016
872016
Xenosiderophore utilization promotes Bacteroides thetaiotaomicron resilience during colitis
W Zhu, MG Winter, L Spiga, ER Hughes, R Chanin, A Mulgaonkar, ...
Cell host & microbe 27 (3), 376-388. e8, 2020
792020
Epithelial-derived reactive oxygen species enable AppBCX-mediated aerobic respiration of Escherichia coli during intestinal inflammation
RB Chanin, MG Winter, L Spiga, ER Hughes, W Zhu, SJ Taylor, ...
Cell host & microbe 28 (6), 780-788. e5, 2020
702020
Colonocyte-derived lactate promotes E. coli fitness in the context of inflammation-associated gut microbiota dysbiosis
SJ Taylor, MG Winter, CC Gillis, LA Silva, AL Dobbins, MK Muramatsu, ...
Microbiome 10 (1), 200, 2022
302022
Lipopolysaccharides belonging to different Salmonella serovars are differentially capable of activating Toll-like receptor 4
D Chessa, L Spiga, N De Riu, P Delaconi, V Mazzarello, G Ganau, ...
Infection and immunity 82 (11), 4553-4562, 2014
272014
Host-Derived Metabolites Modulate Transcription of Salmonella Genes Involved in l-Lactate Utilization during Gut Colonization
CC Gillis, MG Winter, RB Chanin, W Zhu, L Spiga, SE Winter
Infection and immunity 87 (4), 10.1128/iai. 00773-18, 2019
262019
Using enteric pathogens to probe the gut microbiota
L Spiga, SE Winter
Trends in microbiology 27 (3), 243-253, 2019
262019
Iron acquisition by a commensal bacterium modifies host nutritional immunity during Salmonella infection
L Spiga, RT Fansler, YR Perera, NG Shealy, MJ Munneke, HE David, ...
Cell Host & Microbe 31 (10), 1639-1654. e10, 2023
222023
Reshaping of bacterial molecular hydrogen metabolism contributes to the outgrowth of commensal E. coli during gut inflammation
ER Hughes, MG Winter, L Alves da Silva, MK Muramatsu, AG Jimenez, ...
Elife 10, e58609, 2021
162021
Transition metals and host-microbe interactions in the inflamed intestine
W Zhu, L Spiga, S Winter
Biometals 32, 369-384, 2019
152019
Formate oxidation in the intestinal mucus layer enhances fitness of Salmonella enterica serovar Typhimurium
MG Winter, ER Hughes, MK Muramatsu, AG Jimenez, RB Chanin, L Spiga, ...
Mbio 14 (4), e00921-23, 2023
62023
Byproducts of inflammatory radical metabolism provide transient nutrient niches for microbes in the inflamed gut
L Spiga, MG Winter, MK Muramatsu, VK Rojas, RB Chanin, W Zhu, ...
bioRxiv, 2023.12. 08.570695, 2023
22023
Taxonomic and metagenomic analyses define the development of the microbiota in the chick
L Bogomolnaya, M Talamantes, J Rocha, A Nagarajan, W Zhu, L Spiga, ...
Mbio 14 (1), e02444-22, 2023
22023
How microbiological tests reflect bacterial pathogenesis and host adaptation
L Spiga, AG Jimenez, RL Santos, SE Winter
Brazilian Journal of Microbiology 52 (4), 1745-1753, 2021
22021
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